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Dipeptidyl Peptidase-4 Inhibitors for the Potential Treatment of Brain Disorders; A Mini-Review With Special Focus on Linagliptin and Stroke.

Darsalia V, Johansen OE, Lietzau G, Nyström T, Klein T, Patrone C.

Front Neurol. 2019 May 8;10:493. doi: 10.3389/fneur.2019.00493. eCollection 2019. Review.


Efficacy of a peer-led group program for unemployed people with mental health problems: Pilot randomized controlled trial.

Rüsch N, Staiger T, Waldmann T, Dekoj MC, Brosch T, Gabriel L, Bahemann A, Oexle N, Klein T, Nehf L, Becker T.

Int J Soc Psychiatry. 2019 Jun;65(4):333-337. doi: 10.1177/0020764019846171. Epub 2019 May 6.


Mechanisms of GLP-1 receptor-independent renoprotective effects of the dipeptidyl peptidase type 4 inhibitor linagliptin in GLP-1 receptor knockout mice with 5/6 nephrectomy.

Hasan AA, von Websky K, Reichetzeder C, Tsuprykov O, Gaballa MMS, Guo J, Zeng S, Delić D, Tammen H, Klein T, Kleuser B, Hocher B.

Kidney Int. 2019 Jun;95(6):1373-1388. doi: 10.1016/j.kint.2019.01.010. Epub 2019 Feb 27.


Live video rate volumetric OCT imaging of the retina with multi-MHz A-scan rates.

Kolb JP, Draxinger W, Klee J, Pfeiffer T, Eibl M, Klein T, Wieser W, Huber R.

PLoS One. 2019 Mar 28;14(3):e0213144. doi: 10.1371/journal.pone.0213144. eCollection 2019.


Progesterone relates to enhanced incisional acute pain and pinprick hyperalgesia in the luteal phase of female volunteers.

Pogatzki-Zahn EM, Mengersen C, Englbrecht JS, Klein T, Magerl W, Zahn PK.

Pain. 2019 Mar 21. doi: 10.1097/j.pain.0000000000001561. [Epub ahead of print]


Low-budget 3D-printed equipment for continuous flow reactions.

Neumaier JM, Madani A, Klein T, Ziegler T.

Beilstein J Org Chem. 2019 Feb 26;15:558-566. doi: 10.3762/bjoc.15.50. eCollection 2019.


Seasonal Variation in the Incidence of Malignant Glaucoma after Cataract Surgery.

Shute TS, Varma DK, Tam D, Klein T, Moinul P, Ahmed IIK, Sheybani A.

J Ophthalmic Vis Res. 2019 Jan-Mar;14(1):32-37. doi: 10.4103/jovr.jovr_41_18.


Generation of two induced pluripotent stem cell lines from skin fibroblasts of sisters carrying a c.1094C>A variation in the SCN10A gene potentially associated with small fiber neuropathy.

Klein T, Klug K, Henkel L, Kwok CK, Edenhofer F, Klopocki E, Kurth I, Üçeyler N.

Stem Cell Res. 2019 Mar;35:101396. doi: 10.1016/j.scr.2019.101396. Epub 2019 Feb 2.


Urinary Proteomics as a Tool to Identify Kidney Responders to Dipeptidyl Peptidase-4 Inhibition: A Hypothesis-Generating Analysis from the MARLINA-T2D Trial.

Siwy J, Klein T, Rosler M, von Eynatten M.

Proteomics Clin Appl. 2019 Mar;13(2):e1800144. doi: 10.1002/prca.201800144. Epub 2019 Jan 28.


The impact of blood pressure variability and pulse pressure on graft survival and mortality after kidney transplantation.

Pagonas N, Markakis K, Bauer F, Seibert FS, Seidel M, Zidek W, Kykalos S, Sasko B, Klein T, Babel N, Viebahn R, Westhoff TH.

Clin Transplant. 2019 Jan;33(1):e13448. doi: 10.1111/ctr.13448. Epub 2018 Dec 6.


Anti-angiogenic effects of the DPP-4 inhibitor linagliptin via inhibition of VEGFR signalling in the mouse model of oxygen-induced retinopathy.

Kolibabka M, Dietrich N, Klein T, Hammes HP.

Diabetologia. 2018 Nov;61(11):2412-2421. doi: 10.1007/s00125-018-4701-4. Epub 2018 Aug 10.


Breadth of coverage against a panel of 110 invasive disease isolates, immunogenicity and safety for 2 and 3 doses of an investigational MenABCWY vaccine in US adolescents - Results from a randomized, controlled, observer-blind phase II study.

Welsch JA, Senders S, Essink B, Klein T, Smolenov I, Pedotti P, Barbi S, Verma B, Toneatto D.

Vaccine. 2018 Aug 23;36(35):5309-5317. doi: 10.1016/j.vaccine.2018.07.016. Epub 2018 Jul 27.


Differences in kidney-specific DPP-4 inhibition by linagliptin and sitagliptin.

Luippold G, Mark M, Klein T, Amann K, Daniel C.

Diabetes Res Clin Pract. 2018 Sep;143:199-203. doi: 10.1016/j.diabres.2018.07.009. Epub 2018 Jul 18.


Endocytic Trafficking of the Notch Receptor.

Schnute B, Troost T, Klein T.

Adv Exp Med Biol. 2018;1066:99-122. doi: 10.1007/978-3-319-89512-3_6. Review.


Linagliptin unmasks specific antioxidant pathways protective against albuminuria and kidney hypertrophy in a mouse model of diabetes.

Spencer NY, Yang Z, Sullivan JC, Klein T, Stanton RC.

PLoS One. 2018 Jul 6;13(7):e0200249. doi: 10.1371/journal.pone.0200249. eCollection 2018.


Assessment of pain quality reveals distinct differences between nociceptive innervation of low back fascia and muscle in humans.

Schilder A, Magerl W, Klein T, Treede RD.

Pain Rep. 2018 May 30;3(3):e662. doi: 10.1097/PR9.0000000000000662. eCollection 2018 May.


The effect of DPP-4 inhibition to improve functional outcome after stroke is mediated by the SDF-1α/CXCR4 pathway.

Chiazza F, Tammen H, Pintana H, Lietzau G, Collino M, Nyström T, Klein T, Darsalia V, Patrone C.

Cardiovasc Diabetol. 2018 May 19;17(1):60. doi: 10.1186/s12933-018-0702-3.


The human pain system exhibits higher-order plasticity (metaplasticity).

Magerl W, Hansen N, Treede RD, Klein T.

Neurobiol Learn Mem. 2018 Oct;154:112-120. doi: 10.1016/j.nlm.2018.04.003. Epub 2018 Apr 6.


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