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Items: 1 to 20 of 212

1.

Nrf2 in liver toxicology.

Taguchi K, Kensler TW.

Arch Pharm Res. 2019 Nov 28. doi: 10.1007/s12272-019-01192-3. [Epub ahead of print] Review.

PMID:
31782059
2.

Broccoli or Sulforaphane: Is It the Source or Dose That Matters?

Yagishita Y, Fahey JW, Dinkova-Kostova AT, Kensler TW.

Molecules. 2019 Oct 6;24(19). pii: E3593. doi: 10.3390/molecules24193593. Review.

3.

Serum miR-182 is a predictive biomarker for dichotomization of risk of hepatocellular carcinoma in rats.

Livingstone MC, Johnson NM, Roebuck BD, Kensler TW, Groopman JD.

Mol Carcinog. 2019 Nov;58(11):2017-2025. doi: 10.1002/mc.23093. Epub 2019 Aug 2.

PMID:
31373075
4.

Impact of Antioxidant Natural Compounds on the Thyroid Gland and Implication of the Keap1/Nrf2 Signaling Pathway.

Paunkov A, Chartoumpekis DV, Ziros PG, Chondrogianni N, Kensler TW, Sykiotis GP.

Curr Pharm Des. 2019;25(16):1828-1846. doi: 10.2174/1381612825666190701165821.

PMID:
31267862
5.

Qidong: a crucible for studies on liver cancer etiology and prevention.

Chen J, Zhu J, Wang G, Groopman JD, Kensler TW.

Cancer Biol Med. 2019 Feb;16(1):24-37. doi: 10.20892/j.issn.2095-3941.2018.0394.

6.

Nrf2 Ameliorates DDC-Induced Sclerosing Cholangitis and Biliary Fibrosis and Improves the Regenerative Capacity of the Liver.

Fragoulis A, Schenkel J, Herzog M, Schellenberg T, Jahr H, Pufe T, Trautwein C, Kensler TW, Streetz KL, Wruck CJ.

Toxicol Sci. 2019 Jun 1;169(2):485-498. doi: 10.1093/toxsci/kfz055.

PMID:
30825315
7.

Broccoli sprout beverage is safe for thyroid hormonal and autoimmune status: Results of a 12-week randomized trial.

Chartoumpekis DV, Ziros PG, Chen JG, Groopman JD, Kensler TW, Sykiotis GP.

Food Chem Toxicol. 2019 Apr;126:1-6. doi: 10.1016/j.fct.2019.02.004. Epub 2019 Feb 5.

PMID:
30735751
8.

Nrf2 represses the onset of type 1 diabetes in non-obese diabetic mice.

Yagishita Y, Uruno A, Chartoumpekis DV, Kensler TW, Yamamoto M.

J Endocrinol. 2019 Jan 1. pii: JOE-18-0355.R2. doi: 10.1530/JOE-18-0355. [Epub ahead of print]

PMID:
30625116
9.

Therapeutic targeting of the NRF2 and KEAP1 partnership in chronic diseases.

Cuadrado A, Rojo AI, Wells G, Hayes JD, Cousin SP, Rumsey WL, Attucks OC, Franklin S, Levonen AL, Kensler TW, Dinkova-Kostova AT.

Nat Rev Drug Discov. 2019 Apr;18(4):295-317. doi: 10.1038/s41573-018-0008-x. Review.

PMID:
30610225
10.

AACR White Paper: Shaping the Future of Cancer Prevention - A Roadmap for Advancing Science and Public Health.

Lippman SM, Abate-Shen C, Colbert Maresso KL, Colditz GA, Dannenberg AJ, Davidson NE, Disis ML, DuBois RN, Szabo E, Giuliano AR, Hait WN, Lee JJ, Kensler TW, Kramer BS, Limburg P, Maitra A, Martinez ME, Rebbeck TR, Schmitz KH, Vilar E, Hawk ET.

Cancer Prev Res (Phila). 2018 Dec;11(12):735-778. doi: 10.1158/1940-6207.CAPR-18-0421.

11.

Evaluation of 2-Thiothiazolidine-4-Carboxylic Acid, a Common Metabolite of Isothiocyanates, as a Potential Biomarker of Cruciferous Vegetable Intake.

Palliyaguru DL, Salvatore SR, Schopfer FJ, Cheng X, Zhou J, Kensler TW, Wendell SG.

Mol Nutr Food Res. 2019 Feb;63(3):e1801029. doi: 10.1002/mnfr.201801029. Epub 2018 Nov 22.

PMID:
30408325
12.

Activation of Nrf2 in the liver is associated with stress resistance mediated by suppression of the growth hormone-regulated STAT5b transcription factor.

Rooney J, Oshida K, Vasani N, Vallanat B, Ryan N, Chorley BN, Wang X, Bell DA, Wu KC, Aleksunes LM, Klaassen CD, Kensler TW, Corton JC.

PLoS One. 2018 Aug 16;13(8):e0200004. doi: 10.1371/journal.pone.0200004. eCollection 2018.

13.

NFE2-Related Transcription Factor 2 Coordinates Antioxidant Defense with Thyroglobulin Production and Iodination in the Thyroid Gland.

Ziros PG, Habeos IG, Chartoumpekis DV, Ntalampyra E, Somm E, Renaud CO, Bongiovanni M, Trougakos IP, Yamamoto M, Kensler TW, Santisteban P, Carrasco N, Ris-Stalpers C, Amendola E, Liao XH, Rossich L, Thomasz L, Juvenal GJ, Refetoff S, Sykiotis GP.

Thyroid. 2018 Jun;28(6):780-798. doi: 10.1089/thy.2018.0018.

14.

The KEAP1-NRF2 System: a Thiol-Based Sensor-Effector Apparatus for Maintaining Redox Homeostasis.

Yamamoto M, Kensler TW, Motohashi H.

Physiol Rev. 2018 Jul 1;98(3):1169-1203. doi: 10.1152/physrev.00023.2017. Review.

15.

Nrf2 prevents Notch-induced insulin resistance and tumorigenesis in mice.

Chartoumpekis DV, Yagishita Y, Fazzari M, Palliyaguru DL, Rao UN, Zaravinos A, Khoo NK, Schopfer FJ, Weiss KR, Michalopoulos GK, Sipula I, O'Doherty RM, Kensler TW, Wakabayashi N.

JCI Insight. 2018 Mar 8;3(5). pii: 97735. doi: 10.1172/jci.insight.97735.

16.

Nrf2 deletion from adipocytes, but not hepatocytes, potentiates systemic metabolic dysfunction after long-term high-fat diet-induced obesity in mice.

Chartoumpekis DV, Palliyaguru DL, Wakabayashi N, Fazzari M, Khoo NKH, Schopfer FJ, Sipula I, Yagishita Y, Michalopoulos GK, O'Doherty RM, Kensler TW.

Am J Physiol Endocrinol Metab. 2018 Aug 1;315(2):E180-E195. doi: 10.1152/ajpendo.00311.2017. Epub 2018 Feb 27.

17.

NRF2 regulates core and stabilizing circadian clock loops, coupling redox and timekeeping in Mus musculus.

Wible RS, Ramanathan C, Sutter CH, Olesen KM, Kensler TW, Liu AC, Sutter TR.

Elife. 2018 Feb 26;7. pii: e31656. doi: 10.7554/eLife.31656.

18.

Qidong hepatitis B virus infection cohort: a 25-year prospective study in high risk area of primary liver cancer.

Chen T, Qian G, Fan C, Sun Y, Wang J, Lu P, Xue X, Wu Y, Zhang Q, Jin Y, Wu Y, Gan Y, Lu J, Kensler TW, Groopman JD, Tu H.

Hepatoma Res. 2018;4. pii: 4. doi: 10.20517/2394-5079.2017.50. Epub 2018 Jan 26.

19.

Isothiocyanates: Translating the Power of Plants to People.

Palliyaguru DL, Yuan JM, Kensler TW, Fahey JW.

Mol Nutr Food Res. 2018 Sep;62(18):e1700965. doi: 10.1002/mnfr.201700965. Epub 2018 Mar 26. Review.

20.

Pharmacogenomics of Chemically Distinct Classes of Keap1-Nrf2 Activators Identify Common and Unique Gene, Protein, and Pathway Responses In Vivo.

Wible RS, Tran QT, Fathima S, Sutter CH, Kensler TW, Sutter TR.

Mol Pharmacol. 2018 Apr;93(4):297-308. doi: 10.1124/mol.117.110262. Epub 2018 Jan 24.

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