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Items: 19


Coccidioides immitis and posadasii; A review of their biology, genomics, pathogenesis, and host immunity.

Kirkland TN, Fierer J.

Virulence. 2018;9(1):1426-1435. doi: 10.1080/21505594.2018.1509667. Review.


Special Issue: Genomic Data in Pathogenic Fungi.

Kirkland TN.

J Fungi (Basel). 2018 Mar 20;4(1). pii: E40. doi: 10.3390/jof4010040.


The Quest for a Vaccine Against Coccidioidomycosis: A Neglected Disease of the Americas.

Kirkland TN.

J Fungi (Basel). 2016 Dec 16;2(4). pii: E34. doi: 10.3390/jof2040034. Review.


Analysis of Transposable Elements in Coccidioides Species.

Kirkland TN, Muszewska A, Stajich JE.

J Fungi (Basel). 2018 Jan 19;4(1). pii: E13. doi: 10.3390/jof4010013.


A few shared up-regulated genes may influence conidia to yeast transformation in dimorphic fungal pathogens.

Kirkland TN.

Med Mycol. 2016 Aug 1;54(6):648-53. doi: 10.1093/mmy/myw019. Epub 2016 Apr 26.


Gene expression in human fungal pathogen Coccidioides immitis changes as arthroconidia differentiate into spherules and mature.

Viriyakosol S, Singhania A, Fierer J, Goldberg J, Kirkland TN, Woelk CH.

BMC Microbiol. 2013 May 28;13:121. doi: 10.1186/1471-2180-13-121.


Factors regulated by interferon gamma and hypoxia-inducible factor 1A contribute to responses that protect mice from Coccidioides immitis infection.

Woelk CH, Zhang JX, Walls L, Viriyakosol S, Singhania A, Kirkland TN, Fierer J.

BMC Microbiol. 2012 Sep 24;12:218. doi: 10.1186/1471-2180-12-218.


The role of reactive oxygen intermediates in experimental coccidioidomycois in mice.

Margolis DA, Viriyakosol S, Fierer J, Kirkland TN.

BMC Microbiol. 2011 Apr 11;11:71. doi: 10.1186/1471-2180-11-71.


Population genomic sequencing of Coccidioides fungi reveals recent hybridization and transposon control.

Neafsey DE, Barker BM, Sharpton TJ, Stajich JE, Park DJ, Whiston E, Hung CY, McMahan C, White J, Sykes S, Heiman D, Young S, Zeng Q, Abouelleil A, Aftuck L, Bessette D, Brown A, FitzGerald M, Lui A, Macdonald JP, Priest M, Orbach MJ, Galgiani JN, Kirkland TN, Cole GT, Birren BW, Henn MR, Taylor JW, Rounsley SD.

Genome Res. 2010 Jul;20(7):938-46. doi: 10.1101/gr.103911.109. Epub 2010 Jun 1.


Arenimycin, an antibiotic effective against rifampin- and methicillin-resistant Staphylococcus aureus from the marine actinomycete Salinispora arenicola.

Asolkar RN, Kirkland TN, Jensen PR, Fenical W.

J Antibiot (Tokyo). 2010 Jan;63(1):37-9. doi: 10.1038/ja.2009.114. Epub 2009 Nov 20. No abstract available.


Comparative genomic analyses of the human fungal pathogens Coccidioides and their relatives.

Sharpton TJ, Stajich JE, Rounsley SD, Gardner MJ, Wortman JR, Jordar VS, Maiti R, Kodira CD, Neafsey DE, Zeng Q, Hung CY, McMahan C, Muszewska A, Grynberg M, Mandel MA, Kellner EM, Barker BM, Galgiani JN, Orbach MJ, Kirkland TN, Cole GT, Henn MR, Birren BW, Taylor JW.

Genome Res. 2009 Oct;19(10):1722-31. doi: 10.1101/gr.087551.108. Epub 2009 Aug 28.


Characterization of monoclonal antibodies to human soluble MD-2 protein.

Viriyakosol S, McCray PB, Ashbaugh ME, Chu J, Jia HP, Weiss J, Kirkland TN.

Hybridoma (Larchmt). 2006 Dec;25(6):349-57.


Improved protection of mice against lethal respiratory infection with Coccidioides posadasii using two recombinant antigens expressed as a single protein.

Shubitz LF, Yu JJ, Hung CY, Kirkland TN, Peng T, Perrill R, Simons J, Xue J, Herr RA, Cole GT, Galgiani JN.

Vaccine. 2006 Jul 26;24(31-32):5904-11. Epub 2006 Apr 18.


Mutational analysis of membrane and soluble forms of human MD-2.

Viriyakosol S, Tobias PS, Kirkland TN.

J Biol Chem. 2006 Apr 28;281(17):11955-64. Epub 2006 Feb 8.


Molecular and cellular mechanisms of protective immunity to coccidioidomycosis.

Kirkland TN, Raz E, Datta SK.

Vaccine. 2006 Jan 23;24(4):495-500. Epub 2005 Aug 15.


Innate immunity to the pathogenic fungus Coccidioides posadasii is dependent on Toll-like receptor 2 and Dectin-1.

Viriyakosol S, Fierer J, Brown GD, Kirkland TN.

Infect Immun. 2005 Mar;73(3):1553-60.


Lipopolysaccharide (LPS)-binding protein inhibits responses to cell-bound LPS.

Thompson PA, Tobias PS, Viriyakosol S, Kirkland TN, Kitchens RL.

J Biol Chem. 2003 Aug 1;278(31):28367-71. Epub 2003 May 15.


Minimally modified LDL binds to CD14, induces macrophage spreading via TLR4/MD-2, and inhibits phagocytosis of apoptotic cells.

Miller YI, Viriyakosol S, Binder CJ, Feramisco JR, Kirkland TN, Witztum JL.

J Biol Chem. 2003 Jan 17;278(3):1561-8. Epub 2002 Nov 6.

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