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Items: 1 to 20 of 158

1.

Insulin-like growth factor-I receptor and thyroid-associated ophthalmopathy.

Smith TJ, Janssen JAMJL.

Endocr Rev. 2018 Sep 11. doi: 10.1210/er.2018-00066. [Epub ahead of print]

PMID:
30215690
2.

Challenges in Orphan Drug Development: Identification of Effective Therapy for Thyroid-Associated Ophthalmopathy.

Smith TJ.

Annu Rev Pharmacol Toxicol. 2018 Jul 25. doi: 10.1146/annurev-pharmtox-010617-052509. [Epub ahead of print]

PMID:
30044728
3.

CD34- Orbital Fibroblasts From Patients With Thyroid-Associated Ophthalmopathy Modulate TNF-α Expression in CD34+ Fibroblasts and Fibrocytes.

Lu Y, Atkins SJ, Fernando R, Trierweiler A, Mester T, Grisolia ABD, Mou P, Novaes P, Smith TJ.

Invest Ophthalmol Vis Sci. 2018 May 1;59(6):2615-2622. doi: 10.1167/iovs.18-23951.

4.

Slit2 Modulates the Inflammatory Phenotype of Orbit-Infiltrating Fibrocytes in Graves' Disease.

Fernando R, Grisolia ABD, Lu Y, Atkins S, Smith TJ.

J Immunol. 2018 Jun 15;200(12):3942-3949. doi: 10.4049/jimmunol.1800259. Epub 2018 May 11.

PMID:
29752312
5.

New advances in understanding thyroid-associated ophthalmopathy and the potential role for insulin-like growth factor-I receptor.

Smith TJ.

F1000Res. 2018 Feb 1;7:134. doi: 10.12688/f1000research.12787.1. eCollection 2018. Review.

6.

Evaluation of an Internally Controlled Multiplex Tth Endonuclease Cleavage Loop-Mediated Isothermal Amplification (TEC-LAMP) Assay for the Detection of Bacterial Meningitis Pathogens.

Higgins O, Clancy E, Cormican M, Boo TW, Cunney R, Smith TJ.

Int J Mol Sci. 2018 Feb 9;19(2). pii: E524. doi: 10.3390/ijms19020524.

7.

Duplex recombinase polymerase amplification assays incorporating competitive internal controls for bacterial meningitis detection.

Higgins O, Clancy E, Forrest MS, Piepenburg O, Cormican M, Boo TW, O'Sullivan N, McGuinness C, Cafferty D, Cunney R, Smith TJ.

Anal Biochem. 2018 Apr 1;546:10-16. doi: 10.1016/j.ab.2018.01.016. Epub 2018 Jan 31.

PMID:
29378166
8.

IGF1 receptor and thyroid-associated ophthalmopathy.

Mohyi M, Smith TJ.

J Mol Endocrinol. 2018 Jul;61(1):T29-T43. doi: 10.1530/JME-17-0276. Epub 2017 Dec 22. Review.

PMID:
29273685
9.

Subtle modifications to oxytocin produce ligands that retain potency and improved selectivity across species.

Muttenthaler M, Andersson Å, Vetter I, Menon R, Busnelli M, Ragnarsson L, Bergmayr C, Arrowsmith S, Deuis JR, Chiu HS, Palpant NJ, O'Brien M, Smith TJ, Wray S, Neumann ID, Gruber CW, Lewis RJ, Alewood PF.

Sci Signal. 2017 Dec 5;10(508). pii: eaan3398. doi: 10.1126/scisignal.aan3398.

10.

Response to Krieger et al. re: "TSHR/IGF-1R Cross-Talk, Not IGF-1R Stimulating Antibodies, Mediates Graves' Ophthalmopathy Pathogenesis" (Thyroid 2017;27:746-747).

Smith TJ, Janssen JAMJL.

Thyroid. 2017 Nov;27(11):1458-1459. doi: 10.1089/thy.2017.0281. Epub 2017 Sep 28. No abstract available.

PMID:
28847224
11.

De novo triiodothyronine formation from thyrocytes activated by thyroid-stimulating hormone.

Citterio CE, Veluswamy B, Morgan SJ, Galton VA, Banga JP, Atkins S, Morishita Y, Neumann S, Latif R, Gershengorn MC, Smith TJ, Arvan P.

J Biol Chem. 2017 Sep 15;292(37):15434-15444. doi: 10.1074/jbc.M117.784447. Epub 2017 Jul 25.

12.

Update on thyroid-associated Ophthalmopathy with a special emphasis on the ocular surface.

Novaes P, Diniz Grisolia AB, Smith TJ.

Clin Diabetes Endocrinol. 2016 Nov 16;2:19. doi: 10.1186/s40842-016-0037-5. eCollection 2016. Review.

13.

Teprotumumab for Thyroid-Associated Ophthalmopathy.

Smith TJ, Kahaly GJ, Ezra DG, Fleming JC, Dailey RA, Tang RA, Harris GJ, Antonelli A, Salvi M, Goldberg RA, Gigantelli JW, Couch SM, Shriver EM, Hayek BR, Hink EM, Woodward RM, Gabriel K, Magni G, Douglas RS.

N Engl J Med. 2017 May 4;376(18):1748-1761. doi: 10.1056/NEJMoa1614949.

14.

Amplification-free detection of microRNAs via a rapid microarray-based sandwich assay.

Clancy E, Burke M, Arabkari V, Barry T, Kelly H, Dwyer RM, Kerin MJ, Smith TJ.

Anal Bioanal Chem. 2017 May;409(14):3497-3505. doi: 10.1007/s00216-017-0298-6. Epub 2017 Mar 27.

PMID:
28349168
15.

A novel molecular assay using hybridisation probes and melt curve analysis for CALR exon 9 mutation detection in myeloproliferative neoplasms.

Keaney T, O'Connor L, Krawczyk J, Abdelrahman MA, Hayat AH, Murray M, O'Dwyer M, Percy M, Langabeer S, Haslam K, Glynn B, Mullen C, Keady E, Lahiff S, Smith TJ.

J Clin Pathol. 2017 Aug;70(8):662-668. doi: 10.1136/jclinpath-2016-204205. Epub 2017 Jan 31.

PMID:
28143941
16.

Building the Case for Insulin-Like Growth Factor Receptor-I Involvement in Thyroid-Associated Ophthalmopathy.

Smith TJ, Janssen JA.

Front Endocrinol (Lausanne). 2017 Jan 3;7:167. doi: 10.3389/fendo.2016.00167. eCollection 2016. Review.

17.

Graves' Disease.

Smith TJ, Hegedüs L.

N Engl J Med. 2017 Jan 12;376(2):185. doi: 10.1056/NEJMc1614624. No abstract available.

18.

Graves' Disease.

Smith TJ, Hegedüs L.

N Engl J Med. 2016 Oct 20;375(16):1552-1565. Review. No abstract available.

PMID:
27797318
19.

Elevated Serum Tetrac in Graves Disease: Potential Pathogenic Role in Thyroid-Associated Ophthalmopathy.

Fernando R, Placzek E, Reese EA, Placzek AT, Schwartz S, Trierweiler A, Niziol LM, Raychaudhuri N, Atkins S, Scanlan TS, Smith TJ.

J Clin Endocrinol Metab. 2017 Mar 1;102(3):776-785. doi: 10.1210/jc.2016-2762.

20.

Thyrotropin and CD40L Stimulate Interleukin-12 Expression in Fibrocytes: Implications for Pathogenesis of Thyroid-Associated Ophthalmopathy.

Wu T, Mester T, Gupta S, Sun F, Smith TJ, Douglas RS.

Thyroid. 2016 Dec;26(12):1768-1777. Epub 2016 Oct 18.

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