Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 20 of 130

1.

Anti-NASH Drug Development Hitches a Lift on PPAR Agonism.

Boeckmans J, Natale A, Rombaut M, Buyl K, Rogiers V, De Kock J, Vanhaecke T, M Rodrigues R.

Cells. 2019 Dec 21;9(1). pii: E37. doi: 10.3390/cells9010037. Review.

2.

Exposure of HepaRG Cells to Sodium Saccharin Underpins the Importance of Including Non-Hepatotoxic Compounds When Investigating Toxicological Modes of Action Using Metabolomics.

Cuykx M, Beirnaert C, Rodrigues RM, Laukens K, Vanhaecke T, Covaci A.

Metabolites. 2019 Nov 4;9(11). pii: E265. doi: 10.3390/metabo9110265.

3.

Opinion of the Scientific Committee on Consumer safety (SCCS) - Opinion on the safety of cosmetic ingredient salicylic acid (CAS 69-72-7).

Sccs, Panteri E; Sccs members; Sccs external experts.

Regul Toxicol Pharmacol. 2019 Nov;108:104376. doi: 10.1016/j.yrtph.2019.05.001. Epub 2019 Aug 8. No abstract available.

PMID:
31401081
4.

Untargeted liquid chromatography-mass spectrometry metabolomics to assess drug-induced cholestatic features in HepaRG® cells.

Cuykx M, Beirnaert C, Rodrigues RM, Laukens K, Vanhaecke T, Covaci A.

Toxicol Appl Pharmacol. 2019 Sep 15;379:114666. doi: 10.1016/j.taap.2019.114666. Epub 2019 Jul 16.

PMID:
31323262
5.

Transcriptomics data of a human in vitro model of non-alcoholic steatohepatitis exposed to elafibranor.

Boeckmans J, Buyl K, Natale A, Vandenbempt V, Branson S, De Boe V, Rogiers V, De Kock J, Rodrigues RM, Vanhaecke T.

Data Brief. 2019 Jun 3;25:104093. doi: 10.1016/j.dib.2019.104093. eCollection 2019 Aug.

6.
7.
8.

Technological advancements for the development of stem cell-based models for hepatotoxicity testing.

Natale A, Vanmol K, Arslan A, Van Vlierberghe S, Dubruel P, Van Erps J, Thienpont H, Buzgo M, Boeckmans J, De Kock J, Vanhaecke T, Rogiers V, Rodrigues RM.

Arch Toxicol. 2019 Jul;93(7):1789-1805. doi: 10.1007/s00204-019-02465-y. Epub 2019 Apr 29. Review.

PMID:
31037322
9.

Elafibranor restricts lipogenic and inflammatory responses in a human skin stem cell-derived model of NASH.

Boeckmans J, Buyl K, Natale A, Vandenbempt V, Branson S, De Boe V, Rogiers V, De Kock J, Rodrigues RM, Vanhaecke T.

Pharmacol Res. 2019 Jun;144:377-389. doi: 10.1016/j.phrs.2019.04.016. Epub 2019 Apr 24.

PMID:
31028903
10.

Establishment of Sandwich Cultures of Primary Human Hepatocytes.

Gijbels E, Vanhaecke T, Vinken M.

Methods Mol Biol. 2019;1981:325-333. doi: 10.1007/978-1-4939-9420-5_21.

PMID:
31016664
11.

A simple dilute-and-shoot method for screening and simultaneous quantification of nicotine and alkaloid impurities in electronic cigarette refills (e-liquids) by UHPLC-DAD.

Barhdadi S, Desmedt B, Courselle P, Rogiers V, Vanhaecke T, Deconinck E.

J Pharm Biomed Anal. 2019 May 30;169:225-234. doi: 10.1016/j.jpba.2019.03.002. Epub 2019 Mar 2.

PMID:
30877934
12.

Prioritizing substances of genotoxic concern for in-depth safety evaluation using non-animal approaches: The example of food contact materials.

Van Bossuyt M, Van Hoeck E, Vanhaecke T, Rogiers V, Mertens B.

ALTEX. 2019;36(2):215-230. doi: 10.14573/altex.1810011. Epub 2018 Nov 28.

13.

Comment to 'Letter to the editor: Human-based systems: Mechanistic NASH modelling just around the corner?'

Boeckmans J, Natale A, Buyl K, Rogiers V, De Kock J, Vanhaecke T, Rodrigues RM.

Pharmacol Res. 2018 Nov;137:282-283. doi: 10.1016/j.phrs.2018.09.029. Epub 2018 Oct 10. No abstract available.

PMID:
30315967
14.

In vitro assessment of hepatotoxicity by metabolomics: a review.

Cuykx M, Rodrigues RM, Laukens K, Vanhaecke T, Covaci A.

Arch Toxicol. 2018 Oct;92(10):3007-3029. doi: 10.1007/s00204-018-2286-9. Epub 2018 Aug 25. Review.

PMID:
30155722
15.

Human-based systems: Mechanistic NASH modelling just around the corner?

Boeckmans J, Natale A, Buyl K, Rogiers V, De Kock J, Vanhaecke T, Rodrigues RM.

Pharmacol Res. 2018 Aug;134:257-267. doi: 10.1016/j.phrs.2018.06.029. Epub 2018 Jun 30. Review.

16.

Omics-based responses induced by bosentan in human hepatoma HepaRG cell cultures.

Rodrigues RM, Kollipara L, Chaudhari U, Sachinidis A, Zahedi RP, Sickmann A, Kopp-Schneider A, Jiang X, Keun H, Hengstler J, Oorts M, Annaert P, Hoeben E, Gijbels E, De Kock J, Vanhaecke T, Rogiers V, Vinken M.

Arch Toxicol. 2018 Jun;92(6):1939-1952. doi: 10.1007/s00204-018-2214-z. Epub 2018 May 14.

17.

Performance of In Silico Models for Mutagenicity Prediction of Food Contact Materials.

Van Bossuyt M, Van Hoeck E, Raitano G, Vanhaecke T, Benfenati E, Mertens B, Rogiers V.

Toxicol Sci. 2018 Jun 1;163(2):632-638. doi: 10.1093/toxsci/kfy057.

PMID:
29579255
18.

Metabolomics profiling of steatosis progression in HepaRG® cells using sodium valproate.

Cuykx M, Claes L, Rodrigues RM, Vanhaecke T, Covaci A.

Toxicol Lett. 2018 Apr;286:22-30. doi: 10.1016/j.toxlet.2017.12.015. Epub 2018 Jan 31.

PMID:
29355688
19.

Hepatic cells derived from human skin progenitors show a typical phospholipidotic response upon exposure to amiodarone.

Natale A, Boeckmans J, Desmae T, De Boe V, De Kock J, Vanhaecke T, Rogiers V, Rodrigues RM.

Toxicol Lett. 2018 Mar 1;284:184-194. doi: 10.1016/j.toxlet.2017.11.014. Epub 2017 Dec 15.

PMID:
29248575
20.

Development and validation of a HS/GC-MS method for the simultaneous analysis of diacetyl and acetylpropionyl in electronic cigarette refills.

Barhdadi S, Canfyn M, Courselle P, Rogiers V, Vanhaecke T, Deconinck E.

J Pharm Biomed Anal. 2017 Aug 5;142:218-224. doi: 10.1016/j.jpba.2017.04.050. Epub 2017 May 4.

PMID:
28521275

Supplemental Content

Loading ...
Support Center