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Items: 1 to 20 of 208


Non-alcoholic steatohepatitis-related liver tumorigenesis is suppressed in mice lacking hepatic retinoid storage.

Ideta T, Shirakami Y, Ohnishi M, Maruta A, Obara K, Miyazaki T, Kochi T, Sakai H, Tomita H, Tanaka T, Blaner WS, Shimizu M.

Oncotarget. 2017 Aug 7;8(41):70695-70706. doi: 10.18632/oncotarget.19978. eCollection 2017 Sep 19.


Preventive effects of the sodium glucose cotransporter 2 inhibitor tofogliflozin on diethylnitrosamine-induced liver tumorigenesis in obese and diabetic mice.

Obara K, Shirakami Y, Maruta A, Ideta T, Miyazaki T, Kochi T, Sakai H, Tanaka T, Seishima M, Shimizu M.

Oncotarget. 2017 Apr 6;8(35):58353-58363. doi: 10.18632/oncotarget.16874. eCollection 2017 Aug 29.


Promotion of cell proliferation by the proto-oncogene DEK enhances oral squamous cell carcinogenesis through field cancerization.

Nakashima T, Tomita H, Hirata A, Ishida K, Hisamatsu K, Hatano Y, Kanayama T, Niwa A, Noguchi K, Kato K, Miyazaki T, Tanaka T, Shibata T, Hara A.

Cancer Med. 2017 Oct;6(10):2424-2439. doi: 10.1002/cam4.1157. Epub 2017 Aug 23.


A marine bio-functional lipid, fucoxanthinol, attenuates human colorectal cancer stem-like cell tumorigenicity and sphere formation.

Terasaki M, Maeda H, Miyashita K, Tanaka T, Miyamoto S, Mutoh M.

J Clin Biochem Nutr. 2017 Jul;61(1):25-32. doi: 10.3164/jcbn.16-112. Epub 2017 May 16.


Erratum: Tanaka, T. et al. Cimetidine and Clobenpropit Attenuate Inflammation-Associated Colorectal Carcinogenesis in Male ICR Mice. Cancers, 2016, 8, 25.

Tanaka T, Kochi T, Shirakami Y, Mori T, Niwa A, Watanabe N, Moriwaki H, Shimizu M.

Cancers (Basel). 2017 Jul 5;9(7). pii: E80. doi: 10.3390/cancers9070080.


p53 Expression as a Diagnostic Biomarker in Ulcerative Colitis-Associated Cancer.

Kobayashi K, Tomita H, Shimizu M, Tanaka T, Suzui N, Miyazaki T, Hara A.

Int J Mol Sci. 2017 Jun 16;18(6). pii: E1284. doi: 10.3390/ijms18061284. Review.


Peretinoin, an acyclic retinoid, suppresses steatohepatitis and tumorigenesis by activating autophagy in mice fed an atherogenic high-fat diet.

Okada H, Takabatake R, Honda M, Takegoshi K, Yamashita T, Nakamura M, Shirasaki T, Sakai Y, Shimakami T, Nagata N, Takamura T, Tanaka T, Kaneko S.

Oncotarget. 2017 Jun 20;8(25):39978-39993. doi: 10.18632/oncotarget.18116.


Orbital T-Cell Lymphoma with Discrete Enlargements of All Extraocular Muscles Bilaterally in Patient with Moon Face Countenance.

Kawakami H, Mochizuki K, Goto H, Watanabe N, Tanaka T.

Case Rep Ophthalmol Med. 2017;2017:8902162. doi: 10.1155/2017/8902162. Epub 2017 Apr 9.


The different pathogeneses of sporadic adenoma and adenocarcinoma in non-ampullary lesions of the proximal and distal duodenum.

Niwa A, Kuwano S, Tomita H, Kimura K, Orihara Y, Kanayama T, Noguchi K, Hisamatsu K, Nakashima T, Hatano Y, Hirata A, Miyazaki T, Kaneko K, Tanaka T, Hara A.

Oncotarget. 2017 Jun 20;8(25):41078-41090. doi: 10.18632/oncotarget.17051.


Prevention of Colorectal Cancer by Targeting Obesity-Related Disorders and Inflammation.

Shirakami Y, Ohnishi M, Sakai H, Tanaka T, Shimizu M.

Int J Mol Sci. 2017 Apr 26;18(5). pii: E908. doi: 10.3390/ijms18050908. Review.


Branched-chain amino acids prevent hepatic fibrosis and development of hepatocellular carcinoma in a non-alcoholic steatohepatitis mouse model.

Takegoshi K, Honda M, Okada H, Takabatake R, Matsuzawa-Nagata N, Campbell JS, Nishikawa M, Shimakami T, Shirasaki T, Sakai Y, Yamashita T, Takamura T, Tanaka T, Kaneko S.

Oncotarget. 2017 Mar 14;8(11):18191-18205. doi: 10.18632/oncotarget.15304.


Preventive Effects of Pentoxifylline on the Development of Colonic Premalignant Lesions in Obese and Diabetic Mice.

Fukuta K, Shirakami Y, Maruta A, Obara K, Iritani S, Nakamura N, Kochi T, Kubota M, Sakai H, Tanaka T, Shimizu M.

Int J Mol Sci. 2017 Feb 15;18(2). pii: E413. doi: 10.3390/ijms18020413.


Crystallographic structure of recombinant Lactococcus lactis prolidase to support proposed structure-function relationships.

Kgosisejo O, Chen JA, Grochulski P, Tanaka T.

Biochim Biophys Acta. 2017 May;1865(5):473-480. doi: 10.1016/j.bbapap.2017.02.004. Epub 2017 Feb 4.


Different Susceptibilities between Apoe- and Ldlr-Deficient Mice to Inflammation-Associated Colorectal Carcinogenesis.

Tanaka T, Oyama T, Sugie S, Shimizu M.

Int J Mol Sci. 2016 Oct 28;17(11). pii: E1806.


Nonproliferative and Proliferative Lesions of the Gastrointestinal Tract, Pancreas and Salivary Glands of the Rat and Mouse.

Nolte T, Brander-Weber P, Dangler C, Deschl U, Elwell MR, Greaves P, Hailey R, Leach MW, Pandiri AR, Rogers A, Shackelford CC, Spencer A, Tanaka T, Ward JM.

J Toxicol Pathol. 2016;29(1 Suppl):1S-125S. doi: 10.1293/tox.29.1S. Epub 2016 Feb 13. Review.


Cimetidine and Clobenpropit Attenuate Inflammation-Associated Colorectal Carcinogenesis in Male ICR Mice.

Tanaka T, Kochi T, Shirakami Y, Mori T, Kurata A, Watanabe N, Moriwaki H, Shimizu M.

Cancers (Basel). 2016 Feb 20;8(2). pii: E25. doi: 10.3390/cancers8020025.


Sodium alginate prevents progression of non-alcoholic steatohepatitis and liver carcinogenesis in obese and diabetic mice.

Miyazaki T, Shirakami Y, Kubota M, Ideta T, Kochi T, Sakai H, Tanaka T, Moriwaki H, Shimizu M.

Oncotarget. 2016 Mar 1;7(9):10448-58. doi: 10.18632/oncotarget.7249.


Aldehyde dehydrogenase 1A1 in stem cells and cancer.

Tomita H, Tanaka K, Tanaka T, Hara A.

Oncotarget. 2016 Mar 8;7(10):11018-32. doi: 10.18632/oncotarget.6920. Review.


The Role of Indoleamine 2,3-Dioxygenase in Diethylnitrosamine-Induced Liver Carcinogenesis.

Shibata Y, Hara T, Nagano J, Nakamura N, Ohno T, Ninomiya S, Ito H, Tanaka T, Saito K, Seishima M, Shimizu M, Moriwaki H, Tsurumi H.

PLoS One. 2016 Jan 4;11(1):e0146279. doi: 10.1371/journal.pone.0146279. eCollection 2016.


Pentoxifylline prevents nonalcoholic steatohepatitis-related liver pre-neoplasms by inhibiting hepatic inflammation and lipogenesis.

Shirakami Y, Shimizu M, Kubota M, Ohno T, Kochi T, Nakamura N, Sumi T, Tanaka T, Moriwaki H, Seishima M.

Eur J Cancer Prev. 2016 May;25(3):206-15. doi: 10.1097/CEJ.0000000000000172.


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