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Items: 1 to 20 of 65

1.

A 13-week subchronic toxicity study of hexyl acetate in SD rats.

Toyoda T, Cho YM, Matsushita K, Tachibana S, Senuma M, Akagi JI, Ogawa K.

J Toxicol Pathol. 2019 Jul;32(3):205-212. doi: 10.1293/tox.2019-0002. Epub 2019 Mar 29.

2.

A 13-week subchronic toxicity study of vanillin propylene glycol acetal in F344 rats.

Matsushita K, Toyoda T, Morikawa T, Ogawa K.

Food Chem Toxicol. 2019 Oct;132:110643. doi: 10.1016/j.fct.2019.110643. Epub 2019 Jun 26.

PMID:
31252024
3.

Dimethylarsinic acid may promote prostate carcinogenesis in rats.

Suzuki S, Toyoda T, Kato H, Naiki-Ito A, Yamashita Y, Akagi JI, Cho YM, Ogawa K, Takahashi S.

J Toxicol Pathol. 2019 Apr;32(2):73-77. doi: 10.1293/tox.2018-0050. Epub 2018 Dec 21.

4.

Twist1 was detected in mesenchymal cells of mammary fibroadenoma and invasive components of breast carcinoma in rats.

Funahashi S, Okazaki Y, Nagai H, Chew SH, Ogawa K, Toyoda T, Cho YM, Toyokuni S.

J Toxicol Pathol. 2019 Jan;32(1):19-26. doi: 10.1293/tox.2018-0029. Epub 2018 Sep 1.

5.

4-Methylthio-3-butenyl isothiocyanate (MTBITC) induced apoptotic cell death and G2/M cell cycle arrest via ROS production in human esophageal epithelial cancer cells.

Hirata T, Cho YM, Suzuki I, Toyoda T, Akagi JI, Nakamura Y, Numazawa S, Ogawa K.

J Toxicol Sci. 2019;44(2):73-81. doi: 10.2131/jts.44.73.

6.

Immunohistochemistry of γ-H2AX as a method of early detection of urinary bladder carcinogenicity in mice.

Sone M, Toyoda T, Cho YM, Akagi JI, Matsushita K, Mizuta Y, Morikawa T, Nishikawa A, Ogawa K.

J Appl Toxicol. 2019 Jun;39(6):868-876. doi: 10.1002/jat.3775. Epub 2019 Jan 31.

PMID:
30701581
7.

Distinct differences in the mechanisms of mucosal damage and γ-H2AX formation in the rat urinary bladder treated with o-toluidine and o-anisidine.

Toyoda T, Matsushita K, Morikawa T, Yamada T, Miyoshi N, Ogawa K.

Arch Toxicol. 2019 Mar;93(3):753-762. doi: 10.1007/s00204-019-02396-8. Epub 2019 Jan 17.

PMID:
30656379
8.

MEK Inhibitor Reverses Metaplasia and Allows Re-Emergence of Normal Lineages in Helicobacter pylori-Infected Gerbils.

Yang Q, Yasuda T, Choi E, Toyoda T, Roland JT, Uchida E, Yoshida H, Seto Y, Goldenring JR, Nomura S.

Gastroenterology. 2019 Feb;156(3):577-581.e4. doi: 10.1053/j.gastro.2018.10.049. Epub 2018 Nov 2. No abstract available.

PMID:
30391471
9.

A 13-week subchronic toxicity study of 2-ethylbutanal in F344 rats.

Matsushita K, Toyoda T, Morikawa T, Takahashi M, Inoue K, Ogawa K.

Regul Toxicol Pharmacol. 2018 Dec;100:118-126. doi: 10.1016/j.yrtph.2018.10.012. Epub 2018 Oct 22.

PMID:
30359703
10.

Subchronic toxicity evaluation of 5-hexenyl isothiocyanate, a nature identical flavoring substance from Wasabia japonica, in F344/DuCrj rats.

Akagi JI, Cho YM, Mizuta Y, Toyoda T, Ogawa K.

Food Chem Toxicol. 2018 Dec;122:80-86. doi: 10.1016/j.fct.2018.09.060. Epub 2018 Sep 25.

PMID:
30266315
11.

Using RNA-Seq with 11 marker genes to evaluate 1,4-dioxane compared with typical genotoxic and non-genotoxic rat hepatocarcinogens.

Furihata C, Toyoda T, Ogawa K, Suzuki T.

Mutat Res Genet Toxicol Environ Mutagen. 2018 Oct;834:51-55. doi: 10.1016/j.mrgentox.2018.07.002. Epub 2018 Aug 17.

PMID:
30173864
12.

A 13-week subchronic toxicity study of acetaminophen using an obese rat model.

Toyoda T, Cho YM, Akagi JI, Mizuta Y, Matsushita K, Nishikawa A, Imaida K, Ogawa K.

J Toxicol Sci. 2018;43(7):423-433. doi: 10.2131/jts.43.423.

13.

Differential Roles of Rad18 and Chk2 in Genome Maintenance and Skin Carcinogenesis Following UV Exposure.

Tanoue Y, Toyoda T, Sun J, Mustofa MK, Tateishi C, Endo S, Motoyama N, Araki K, Wu D, Okuno Y, Tsukamoto T, Takeya M, Ihn H, Vaziri C, Tateishi S.

J Invest Dermatol. 2018 Dec;138(12):2550-2557. doi: 10.1016/j.jid.2018.05.015. Epub 2018 May 31.

14.

Size-dependent acute toxicity of silver nanoparticles in mice.

Cho YM, Mizuta Y, Akagi JI, Toyoda T, Sone M, Ogawa K.

J Toxicol Pathol. 2018 Jan;31(1):73-80. doi: 10.1293/tox.2017-0043. Epub 2017 Nov 19.

15.

Hypersensitivity of mouse embryonic fibroblast cells defective for DNA polymerases η, ι and κ to various genotoxic compounds: Its potential for application in chemical genotoxic screening.

Akagi J, Yokoi M, Cho YM, Toyoda T, Ohmori H, Hanaoka F, Ogawa K.

DNA Repair (Amst). 2018 Jan;61:76-85. doi: 10.1016/j.dnarep.2017.11.006. Epub 2017 Nov 26.

16.

4-Methylthio-3-butenyl isothiocyanate mediates nuclear factor (erythroid-derived 2)-like 2 activation by regulating reactive oxygen species production in human esophageal epithelial cells.

Hirata T, Cho YM, Suzuki I, Toyoda T, Akagi JI, Nakamura Y, Numazawa S, Ogawa K.

Food Chem Toxicol. 2018 Jan;111:295-301. doi: 10.1016/j.fct.2017.11.022. Epub 2017 Nov 16.

PMID:
29155359
17.

Prevention of Gastric Cancer: Eradication of Helicobacter Pylori and Beyond.

Tsukamoto T, Nakagawa M, Kiriyama Y, Toyoda T, Cao X.

Int J Mol Sci. 2017 Aug 3;18(8). pii: E1699. doi: 10.3390/ijms18081699. Review.

18.

Spontaneous infarcted adenoma of the mammary gland in a Wistar Hannover GALAS rat.

Matsushita K, Toyoda T, Inoue K, Morikawa T, Sone M, Ogawa K.

J Toxicol Pathol. 2017 Jan;30(1):57-62. doi: 10.1293/tox.2016-0042. Epub 2016 Oct 15.

19.

Altered susceptibility of an obese rat model to 13-week subchronic toxicity induced by 3-monochloropropane-1,2-diol.

Toyoda T, Cho YM, Akagi JI, Mizuta Y, Matsushita K, Nishikawa A, Imaida K, Ogawa K.

J Toxicol Sci. 2017;42(1):1-11. doi: 10.2131/jts.42.1.

20.

Degree of methylation burden is determined by the exposure period to carcinogenic factors.

Takeshima H, Niwa T, Toyoda T, Wakabayashi M, Yamashita S, Ushijima T.

Cancer Sci. 2017 Mar;108(3):316-321. doi: 10.1111/cas.13136.

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