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Items: 1 to 20 of 87

1.

Chronic treatment of JTP-109192, a novel G-protein coupled receptor 119 agonist, improves metabolic abnormalities in Zucker Fatty rats.

Tadaki H, Sasase T, Fukuda S, Toriniwa Y, Harada K, Ohta T, Yamada T.

Clin Exp Pharmacol Physiol. 2019 Aug 5. doi: 10.1111/1440-1681.13152. [Epub ahead of print]

PMID:
31380572
2.

Cloning, expression, and characterization of novel GH5 endoglucanases from Thermobifida alba AHK119.

Ohta T, Horie H, Matsu-Ura A, Kawai F.

J Biosci Bioeng. 2019 May;127(5):554-562. doi: 10.1016/j.jbiosc.2018.10.015. Epub 2018 Dec 2.

PMID:
30514616
3.

Hepatic lesions induced by feeding Western diets to Zucker fatty rats, an insulin-resistant model.

Saito T, Toriniwa Y, Ishii Y, Uemura A, Miyajima K, Uno K, Shirai Y, Nakae D, Ohta T.

J Toxicol Pathol. 2018 Oct;31(4):283-291. doi: 10.1293/tox.2018-0016. Epub 2018 Sep 2.

4.

Spontaneously Diabetic Torii (SDT) Fatty Rat, a Novel Animal Model of Type 2 Diabetes Mellitus, Shows Blunted Circadian Rhythms and Melatonin Secretion.

Sakimura K, Maekawa T, Kume SI, Ohta T.

Int J Endocrinol. 2018 Sep 23;2018:9065690. doi: 10.1155/2018/9065690. eCollection 2018.

5.

Pathophysiological abnormalities in the brains of Spontaneously Diabetic Torii-Lepr fa (SDT fatty) rats, a novel type 2 diabetic model.

Maekawa T, Ohta T, Kume S.

J Vet Med Sci. 2018 Sep 13;80(9):1385-1391. doi: 10.1292/jvms.18-0296. Epub 2018 Jul 17.

6.

Depression-related behavioural and neuroendocrine changes in the Spontaneously Diabetic Torii (SDT) fatty rat, an animal model of type 2 diabetes mellitus.

Sakimura K, Maekawa T, Sasagawa K, Ishii Y, Kume SI, Ohta T.

Clin Exp Pharmacol Physiol. 2018 May 14. doi: 10.1111/1440-1681.12965. [Epub ahead of print]

PMID:
29757463
7.

Pathophysiological analyses of skeletal muscle in obese type 2 diabetes SDT fatty rats.

Kemmochi Y, Ohta T, Motohashi Y, Kaneshige A, Katsumi S, Kakimoto K, Yasui Y, Anagawa-Nakamura A, Toyoda K, Taniai-Riya E, Takahashi A, Shoda T, Yamada T.

J Toxicol Pathol. 2018 Apr;31(2):113-123. doi: 10.1293/tox.2017-0064. Epub 2018 Feb 14.

8.

Is the Occlusion Site of the Lenticulostriate Artery Identified on Admission Related to Clinical Prognosis in Patients with Lacunar Stroke?

Naganuma M, Inatomi Y, Nakajima M, Ohta T, Yonehara T, Ando Y.

J Stroke Cerebrovasc Dis. 2018 Jul;27(7):2035-2042. doi: 10.1016/j.jstrokecerebrovasdis.2018.02.058. Epub 2018 Apr 17.

PMID:
29678637
9.

Investigation of pharmacological responses to anti-diabetic drugs in female Spontaneously Diabetic Torii (SDT) fatty rats, a new nonalcoholic steatohepatitis (NASH) model.

Toriniwa Y, Saito T, Miyajima K, Ishii Y, Uno K, Maekawa T, Matsui T, Kume S, Yamada T, Ohta T.

J Vet Med Sci. 2018 Jun 6;80(6):878-885. doi: 10.1292/jvms.18-0119. Epub 2018 Apr 10.

10.

Effects on Glycemic Control in Impaired Wound Healing in Spontaneously Diabetic Torii (SDT) Fatty Rats.

Katsuhiro M, Hui Teoh S, Yamashiro H, Shinohara M, Fatchiyah F, Ohta T, Yamada T.

Med Arch. 2018 Feb;72(1):4-8. doi: 10.5455/medarh.2018.72.4-8.

11.

Assessment of Pharmacological Responses to an Anti-diabetic Drug in a New Obese Type 2 Diabetic Rat Model.

Murai Y, Ohta T, Tadaki H, Miyajima K, Shinohara M, Fatchiyah F, Yamada T.

Med Arch. 2017 Dec;71(6):380-384. doi: 10.5455/medarh.2017.71.380-384.

12.

JTE-852, a novel spleen tyrosine kinase inhibitor, blocks antigen-induced allergic reactions in rats.

Kato T, Ohta T, Iwasaki H, Kobayashi H, Matsuo A, Hata T, Matsushita M.

J Vet Med Sci. 2018 Mar 24;80(3):465-472. doi: 10.1292/jvms.17-0659. Epub 2018 Jan 26.

13.

JTE-852, a novel spleen tyrosine kinase inhibitor, blocks immunoglobulin G-mediated cellular responses and autoimmune reactions in vivo.

Kato T, Ohta T, Iwasaki H, Kobayashi H, Matsuo A, Hata T, Matsushita M.

Life Sci. 2017 Dec 15;191:166-174. doi: 10.1016/j.lfs.2017.10.029. Epub 2017 Oct 19.

PMID:
29056373
14.

Pathophysiological profiles of SDT fatty rats, a potential new diabetic peripheral neuropathy model.

Maekawa T, Tadaki H, Sasase T, Motohashi Y, Miyajima K, Ohta T, Kume S.

J Pharmacol Toxicol Methods. 2017 Nov - Dec;88(Pt 2):160-166. doi: 10.1016/j.vascn.2017.09.257. Epub 2017 Sep 29.

PMID:
28970182
15.

Hepatocellular adenoma with severe fatty change in a male Spontaneously Diabetic Torii rat.

Taniai-Riya E, Miyajima K, Kakimoto K, Ohta T, Yasui Y, Kemmochi Y, Anagawa-Nakamura A, Toyoda K, Takahashi A, Shoda T.

J Toxicol Pathol. 2017 Jan;30(1):69-73. doi: 10.1293/tox.2016-0051. Epub 2016 Oct 27.

16.

Endurance of larch forest ecosystems in eastern Siberia under warming trends.

Sato H, Kobayashi H, Iwahana G, Ohta T.

Ecol Evol. 2016 Jul 22;6(16):5690-704. doi: 10.1002/ece3.2285. eCollection 2016 Aug.

17.

Identification of genes showing differential expression profile associated with growth rate in skeletal muscle tissue of Landrace weanling pig.

Komatsu Y, Sukegawa S, Yamashita M, Katsuda N, Tong B, Ohta T, Kose H, Yamada T.

J Genet. 2016 Jun;95(2):341-7.

18.

Maternal high-fat diet promotes onset of diabetes in rat offspring.

Ohta T, Toriniwa Y, Ryumon N, Inaba N, Hirao T, Yamanaka S, Maeno T, Sakakibara W, Sumikawa M, Chiba K, Nakamura A, Miyajima K, Fatchiyah F, Yamada T.

Anim Sci J. 2017 Jan;88(1):149-155. doi: 10.1111/asj.12606. Epub 2016 May 5.

PMID:
27145882
19.

Intrajejunal infusion of 2-monoacylglycerol reduced food intake without inducing diarrhea in rats.

Okuma C, Ohta T, Ito M, Tadaki H, Oda T, Kume S, Nishiu J, Kakutani M.

J Pharmacol Sci. 2016 Feb;130(2):136-8. doi: 10.1016/j.jphs.2016.01.004. Epub 2016 Jan 20.

20.

JTT-130, a novel intestine-specific inhibitor of microsomal triglyceride transfer protein, ameliorates lipid metabolism and attenuates atherosclerosis in hyperlipidemic animal models.

Mera Y, Kawai T, Ogawa N, Odani N, Sasase T, Miyajima K, Ohta T, Kakutani M.

J Pharmacol Sci. 2015 Nov;129(3):169-76. doi: 10.1016/j.jphs.2015.10.004. Epub 2015 Oct 20.

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