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Items: 1 to 20 of 35


Improved Oxygen Supply to Multicellular Spheroids Using A Gas-permeable Plate and Embedded Hydrogel Beads.

Mihara H, Kugawa M, Sayo K, Tao F, Shinohara M, Nishikawa M, Sakai Y, Akama T, Kojima N.

Cells. 2019 May 31;8(6). pii: E525. doi: 10.3390/cells8060525.


Fibro-Adipogenic Remodeling of the Diaphragm in Obesity-Associated Respiratory Dysfunction.

Buras ED, Converso-Baran K, Davis CS, Akama T, Hikage F, Michele DE, Brooks SV, Chun TH.

Diabetes. 2019 Jan;68(1):45-56. doi: 10.2337/db18-0209. Epub 2018 Oct 25.


Transcription factor 21 (TCF21) promotes proinflammatory interleukin 6 expression and extracellular matrix remodeling in visceral adipose stem cells.

Akama T, Chun TH.

J Biol Chem. 2018 Apr 27;293(17):6603-6610. doi: 10.1074/jbc.RA117.000456. Epub 2018 Mar 14.


Membrane-Tethered Metalloproteinase Expressed by Vascular Smooth Muscle Cells Limits the Progression of Proliferative Atherosclerotic Lesions.

Barnes RH 2nd, Akama T, Öhman MK, Woo MS, Bahr J, Weiss SJ, Eitzman DT, Chun TH.

J Am Heart Assoc. 2017 Jul 22;6(7). pii: e003693. doi: 10.1161/JAHA.116.003693.


Designing 3-D Adipospheres for Quantitative Metabolic Study.

Akama T, Leung BM, Labuz J, Takayama S, Chun TH.

Methods Mol Biol. 2017;1566:177-183. doi: 10.1007/978-1-4939-6820-6_17.


A Novel Role for Flotillin-Containing Lipid Rafts in Negative-Feedback Regulation of Thyroid-Specific Gene Expression by Thyroglobulin.

Luo Y, Akama T, Okayama A, Yoshihara A, Sue M, Oda K, Hayashi M, Ishido Y, Hirano H, Hiroi N, Katoh R, Suzuki K.

Thyroid. 2016 Nov;26(11):1630-1639.


Phosphatidylinositol 3-Kinase-Associated Protein (PI3KAP)/XB130 Crosslinks Actin Filaments through Its Actin Binding and Multimerization Properties In Vitro and Enhances Endocytosis in HEK293 Cells.

Yamanaka D, Akama T, Chida K, Minami S, Ito K, Hakuno F, Takahashi S.

Front Endocrinol (Lausanne). 2016 Jul 11;7:89. doi: 10.3389/fendo.2016.00089. eCollection 2016.


The exocyst complex regulates free fatty acid uptake by adipocytes.

Inoue M, Akama T, Jiang Y, Chun TH.

PLoS One. 2015 Mar 13;10(3):e0120289. doi: 10.1371/journal.pone.0120289. eCollection 2015.


Thyroglobulin increases thyroid cell proliferation via the suppression of specific microRNAs.

Akama T, Luo Y, Sellitti DF, Kawashima A, Tanigawa K, Yoshihara A, Ishido Y, Nakamura K, Tanoue A, Suzuki K.

Mol Endocrinol. 2014 Mar;28(3):368-79. doi: 10.1210/me.2013-1266. Epub 2014 Jan 30.


Leprosy as a model of immunity.

Degang Y, Nakamura K, Akama T, Ishido Y, Luo Y, Ishii N, Suzuki K.

Future Microbiol. 2014;9(1):43-54. doi: 10.2217/fmb.13.140.


Design of tiling arrays and their application to bacterial transcriptome analysis.

Akama T, Nakamura K, Tanoue A, Suzuki K.

Methods Mol Biol. 2013;1067:23-34. doi: 10.1007/978-1-62703-607-8_2.


Comprehensive analysis of prokaryotes in environmental water using DNA microarray analysis and whole genome amplification.

Akama T, Kawashima A, Tanigawa K, Hayashi M, Ishido Y, Luo Y, Hata A, Fujitani N, Ishii N, Suzuki K.

Pathogens. 2013 Oct 30;2(4):591-605. doi: 10.3390/pathogens2040591.


Clofazimine modulates the expression of lipid metabolism proteins in Mycobacterium leprae-infected macrophages.

Degang Y, Akama T, Hara T, Tanigawa K, Ishido Y, Gidoh M, Makino M, Ishii N, Suzuki K.

PLoS Negl Trop Dis. 2012;6(12):e1936. doi: 10.1371/journal.pntd.0001936. Epub 2012 Dec 6.


Demonstration of innate immune responses in the thyroid gland: potential to sense danger and a possible trigger for autoimmune reactions.

Kawashima A, Yamazaki K, Hara T, Akama T, Yoshihara A, Sue M, Tanigawa K, Wu H, Ishido Y, Takeshita F, Ishii N, Sato K, Suzuki K.

Thyroid. 2013 Apr;23(4):477-87. doi: 10.1089/thy.2011.0480. Epub 2013 Mar 18.


Regulation of dual oxidase expression and H2O2 production by thyroglobulin.

Yoshihara A, Hara T, Kawashima A, Akama T, Tanigawa K, Wu H, Sue M, Ishido Y, Hiroi N, Ishii N, Yoshino G, Suzuki K.

Thyroid. 2012 Oct;22(10):1054-62. doi: 10.1089/thy.2012.0003. Epub 2012 Aug 8.


Propylthiouracil increases sodium/iodide symporter gene expression and iodide uptake in rat thyroid cells in the absence of TSH.

Sue M, Akama T, Kawashima A, Nakamura H, Hara T, Tanigawa K, Wu H, Yoshihara A, Ishido Y, Hiroi N, Yoshino G, Kohn LD, Ishii N, Suzuki K.

Thyroid. 2012 Aug;22(8):844-52. doi: 10.1089/thy.2011.0290.


Essential role of hormone-sensitive lipase (HSL) in the maintenance of lipid storage in Mycobacterium leprae-infected macrophages.

Tanigawa K, Degang Y, Kawashima A, Akama T, Yoshihara A, Ishido Y, Makino M, Ishii N, Suzuki K.

Microb Pathog. 2012 May;52(5):285-91.


Phosphatidylinositol 3-kinase-binding protein, PI3KAP/XB130, is required for cAMP-induced amplification of IGF mitogenic activity in FRTL-5 thyroid cells.

Yamanaka D, Akama T, Fukushima T, Nedachi T, Kawasaki C, Chida K, Minami S, Suzuki K, Hakuno F, Takahashi S.

Mol Endocrinol. 2012 Jun;26(6):1043-55. doi: 10.1210/me.2011-1349. Epub 2012 Apr 11.


Thyroglobulin (Tg) activates MAPK pathway to induce thyroid cell growth in the absence of TSH, insulin and serum.

Sue M, Hayashi M, Kawashima A, Akama T, Tanigawa K, Yoshihara A, Hara T, Ishido Y, Ito T, Takahashi S, Ishii N, Suzuki K.

Biochem Biophys Res Commun. 2012 Apr 13;420(3):611-5. doi: 10.1016/j.bbrc.2012.03.046. Epub 2012 Mar 16.


Identification of microRNAs that mediate thyroid cell growth induced by TSH.

Akama T, Sue M, Kawashima A, Wu H, Tanigawa K, Suzuki S, Hayashi M, Yoshihara A, Ishido Y, Ishii N, Suzuki K.

Mol Endocrinol. 2012 Mar;26(3):493-501. doi: 10.1210/me.2011-1004. Epub 2012 Feb 2.

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