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Items: 1 to 20 of 53


Extracellular Vesicles Enriched with Moonlighting Metalloproteinase Are Highly Transmissive, Pro-Tumorigenic, and Trans-Activates Cellular Communication Network Factor (CCN2/CTGF): CRISPR against Cancer.

Okusha Y, Eguchi T, Tran MT, Sogawa C, Yoshida K, Itagaki M, Taha EA, Ono K, Aoyama E, Okamura H, Kozaki KI, Calderwood SK, Takigawa M, Okamoto K.

Cancers (Basel). 2020 Apr 4;12(4). pii: E881. doi: 10.3390/cancers12040881.


Cell Stress Induced Stressome Release Including Damaged Membrane Vesicles and Extracellular HSP90 by Prostate Cancer Cells.

Eguchi T, Sogawa C, Ono K, Matsumoto M, Tran MT, Okusha Y, Lang BJ, Okamoto K, Calderwood SK.

Cells. 2020 Mar 19;9(3). pii: E755. doi: 10.3390/cells9030755.


A Novel Model of Cancer Drug Resistance: Oncosomal Release of Cytotoxic and Antibody-Based Drugs.

Eguchi T, Taha EA, Calderwood SK, Ono K.

Biology (Basel). 2020 Mar 5;9(3). pii: E47. doi: 10.3390/biology9030047. Review.


Antiparkinson Drug Benztropine Suppresses Tumor Growth, Circulating Tumor Cells, and Metastasis by Acting on SLC6A3/DAT and Reducing STAT3.

Sogawa C, Eguchi T, Tran MT, Ishige M, Trin K, Okusha Y, Taha EA, Lu Y, Kawai H, Sogawa N, Takigawa M, Calderwood SK, Okamoto K, Kozaki KI.

Cancers (Basel). 2020 Feb 24;12(2). pii: E523. doi: 10.3390/cancers12020523.


Outer membrane vesicles of Porphyromonas gingivalis attenuate insulin sensitivity by delivering gingipains to the liver.

Seyama M, Yoshida K, Yoshida K, Fujiwara N, Ono K, Eguchi T, Kawai H, Guo J, Weng Y, Haoze Y, Uchibe K, Ikegame M, Sasaki A, Nagatsuka H, Okamoto K, Okamura H, Ozaki K.

Biochim Biophys Acta Mol Basis Dis. 2020 Jun 1;1866(6):165731. doi: 10.1016/j.bbadis.2020.165731. Epub 2020 Feb 20.


Adenosquamous carcinoma development as a recurrence of squamous cell carcinoma in the oral floor: A case report.

Eguchi T, Basugi A, Kanai I, Miyata Y, Suzuki T, Hamada Y.

Medicine (Baltimore). 2019 Oct;98(43):e17688. doi: 10.1097/MD.0000000000017688.


Roles of Extracellular HSPs as Biomarkers in Immune Surveillance and Immune Evasion.

Taha EA, Ono K, Eguchi T.

Int J Mol Sci. 2019 Sep 17;20(18). pii: E4588. doi: 10.3390/ijms20184588. Review.


Tumor Angiogenic Inhibition Triggered Necrosis (TAITN) in Oral Cancer.

Yoshida S, Kawai H, Eguchi T, Sukegawa S, Oo MW, Anqi C, Takabatake K, Nakano K, Okamoto K, Nagatsuka H.

Cells. 2019 Jul 22;8(7). pii: E761. doi: 10.3390/cells8070761.


MZF1 and SCAND1 Reciprocally Regulate CDC37 Gene Expression in Prostate Cancer.

Eguchi T, Prince TL, Tran MT, Sogawa C, Lang BJ, Calderwood SK.

Cancers (Basel). 2019 Jun 8;11(6). pii: E792. doi: 10.3390/cancers11060792.


A Reporter System Evaluates Tumorigenesis, Metastasis, β-catenin/MMP Regulation, and Druggability.

Sogawa C, Eguchi T, Okusha Y, Ono K, Ohyama K, Iizuka M, Kawasaki R, Hamada Y, Takigawa M, Sogawa N, Okamoto K, Kozaki KI.

Tissue Eng Part A. 2019 Oct;25(19-20):1413-1425. doi: 10.1089/ten.TEA.2018.0348. Epub 2019 Jun 14.


Multiple oral ulcers caused by incorrect use of oral bisphosphonate in a patient with dementia: A case report.

Eguchi T, Basugi A, Kanai I, Miyata Y, Hamada Y.

Gerodontology. 2019 Mar;36(1):82-84. doi: 10.1111/ger.12378. Epub 2018 Nov 20.


Nicotine promotes lymph node metastasis and cetuximab resistance in head and neck squamous cell carcinoma.

Shimizu R, Ibaragi S, Eguchi T, Kuwajima D, Kodama S, Nishioka T, Okui T, Obata K, Takabatake K, Kawai H, Ono K, Okamoto K, Nagatsuka H, Sasaki A.

Int J Oncol. 2019 Jan;54(1):283-294. doi: 10.3892/ijo.2018.4631. Epub 2018 Nov 12.


Carcinogenic epithelial-mesenchymal transition initiated by oral cancer exosomes is inhibited by anti-EGFR antibody cetuximab.

Fujiwara T, Eguchi T, Sogawa C, Ono K, Murakami J, Ibaragi S, Asaumi JI, Calderwood SK, Okamoto K, Kozaki KI.

Oral Oncol. 2018 Nov;86:251-257. doi: 10.1016/j.oraloncology.2018.09.030. Epub 2018 Oct 5.


Depletion of Lipid Efflux Pump ABCG1 Triggers the Intracellular Accumulation of Extracellular Vesicles and Reduces Aggregation and Tumorigenesis of Metastatic Cancer Cells.

Namba Y, Sogawa C, Okusha Y, Kawai H, Itagaki M, Ono K, Murakami J, Aoyama E, Ohyama K, Asaumi JI, Takigawa M, Okamoto K, Calderwood SK, Kozaki KI, Eguchi T.

Front Oncol. 2018 Oct 10;8:376. doi: 10.3389/fonc.2018.00376. eCollection 2018.


Anti-EGFR antibody cetuximab is secreted by oral squamous cell carcinoma and alters EGF-driven mesenchymal transition.

Fujiwara T, Eguchi T, Sogawa C, Ono K, Murakami J, Ibaragi S, Asaumi JI, Okamoto K, Calderwood SK, Kozaki KI.

Biochem Biophys Res Commun. 2018 Sep 10;503(3):1267-1272. doi: 10.1016/j.bbrc.2018.07.035. Epub 2018 Jul 13.


Malignant external otitis following radiotherapy for oral cancer: A case report.

Eguchi T, Basugi A, Kanai I, Miyata Y, Nasuno T, Hamada Y.

Medicine (Baltimore). 2018 May;97(21):e10898. doi: 10.1097/MD.0000000000010898.


HSP-enriched properties of extracellular vesicles involve survival of metastatic oral cancer cells.

Ono K, Eguchi T, Sogawa C, Calderwood SK, Futagawa J, Kasai T, Seno M, Okamoto K, Sasaki A, Kozaki KI.

J Cell Biochem. 2018 Sep;119(9):7350-7362. doi: 10.1002/jcb.27039. Epub 2018 May 16.


The intranuclear PEX domain of MMP involves proliferation, migration, and metastasis of aggressive adenocarcinoma cells.

Okusha Y, Eguchi T, Sogawa C, Okui T, Nakano K, Okamoto K, Kozaki KI.

J Cell Biochem. 2018 Sep;119(9):7363-7376. doi: 10.1002/jcb.27040. Epub 2018 May 15.


Genotoxic stress induces Sca-1-expressing metastatic mammary cancer cells.

Gong J, Lang BJ, Weng D, Eguchi T, Murshid A, Borges TJ, Doshi S, Song B, Stevenson MA, Calderwood SK.

Mol Oncol. 2018 Aug;12(8):1249-1263. doi: 10.1002/1878-0261.12321. Epub 2018 Jun 13.


Organoids with cancer stem cell-like properties secrete exosomes and HSP90 in a 3D nanoenvironment.

Eguchi T, Sogawa C, Okusha Y, Uchibe K, Iinuma R, Ono K, Nakano K, Murakami J, Itoh M, Arai K, Fujiwara T, Namba Y, Murata Y, Ohyama K, Shimomura M, Okamura H, Takigawa M, Nakatsura T, Kozaki KI, Okamoto K, Calderwood SK.

PLoS One. 2018 Feb 7;13(2):e0191109. doi: 10.1371/journal.pone.0191109. eCollection 2018.

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