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Items: 1 to 20 of 45

1.

Physical properties of the photodamaged human skin dermis: Rougher collagen surface and stiffer/harder mechanical properties.

Shao Y, Qin Z, Alexander Wilks J, Balimunkwe RM, Fisher GJ, Voorhees JJ, Quan T.

Exp Dermatol. 2018 Jun 29. doi: 10.1111/exd.13728. [Epub ahead of print]

PMID:
29957839
2.

Actin cytoskeleton assembly regulates collagen production via TGF-β type II receptor in human skin fibroblasts.

Qin Z, Fisher GJ, Voorhees JJ, Quan T.

J Cell Mol Med. 2018 Sep;22(9):4085-4096. doi: 10.1111/jcmm.13685. Epub 2018 Jun 11.

3.

YAP/TAZ regulates TGF-β/Smad3 signaling by induction of Smad7 via AP-1 in human skin dermal fibroblasts.

Qin Z, Xia W, Fisher GJ, Voorhees JJ, Quan T.

Cell Commun Signal. 2018 Apr 25;16(1):18. doi: 10.1186/s12964-018-0232-3.

4.

Extracellular matrix regulation of fibroblast function: redefining our perspective on skin aging.

Cole MA, Quan T, Voorhees JJ, Fisher GJ.

J Cell Commun Signal. 2018 Mar;12(1):35-43. doi: 10.1007/s12079-018-0459-1. Epub 2018 Feb 17. Review.

5.

Ezrin regulates skin fibroblast size/mechanical properties and YAP-dependent proliferation.

Quan C, Yan Y, Qin Z, Lin Z, Quan T.

J Cell Commun Signal. 2018 Sep;12(3):549-560. doi: 10.1007/s12079-017-0406-6. Epub 2017 Sep 9.

6.

Cell-size-dependent upregulation of HGF expression in dermal fibroblasts: Impact on human skin connective tissue aging.

Qin Z, Worthen CA, Quan T.

J Dermatol Sci. 2017 Dec;88(3):289-297. doi: 10.1016/j.jdermsci.2017.08.003. Epub 2017 Aug 4.

PMID:
28826691
7.

Smad3-dependent CCN2 mediates fibronectin expression in human skin dermal fibroblasts.

Purohit T, Qin Z, Quan C, Lin Z, Quan T.

PLoS One. 2017 Mar 7;12(3):e0173191. doi: 10.1371/journal.pone.0173191. eCollection 2017. Erratum in: PLoS One. 2017 May 9;12 (5):e0177611.

8.

PI3K/mTOR dual inhibitor BEZ235 and histone deacetylase inhibitor Trichostatin A synergistically exert anti-tumor activity in breast cancer.

Chen L, Jin T, Zhu K, Piao Y, Quan T, Quan C, Lin Z.

Oncotarget. 2017 Feb 14;8(7):11937-11949. doi: 10.18632/oncotarget.14442.

9.

Superior efficacy of co-treatment with the dual PI3K/mTOR inhibitor BEZ235 and histone deacetylase inhibitor Trichostatin A against NSCLC.

Piao J, Chen L, Quan T, Li L, Quan C, Piao Y, Jin T, Lin Z.

Oncotarget. 2016 Sep 13;7(37):60169-60180. doi: 10.18632/oncotarget.11109.

10.

Smad3-dependent regulation of type I collagen in human dermal fibroblasts: Impact on human skin connective tissue aging.

Purohit T, He T, Qin Z, Li T, Fisher GJ, Yan Y, Voorhees JJ, Quan T.

J Dermatol Sci. 2016 Jul;83(1):80-3. doi: 10.1016/j.jdermsci.2016.04.004. Epub 2016 Apr 20. No abstract available.

PMID:
27132061
11.

Alterations of Dermal Connective Tissue Collagen in Diabetes: Molecular Basis of Aged-Appearing Skin.

Argyropoulos AJ, Robichaud P, Balimunkwe RM, Fisher GJ, Hammerberg C, Yan Y, Quan T.

PLoS One. 2016 Apr 22;11(4):e0153806. doi: 10.1371/journal.pone.0153806. eCollection 2016.

12.

Reduction of fibroblast size/mechanical force down-regulates TGF-β type II receptor: implications for human skin aging.

Fisher GJ, Shao Y, He T, Qin Z, Perry D, Voorhees JJ, Quan T.

Aging Cell. 2016 Feb;15(1):67-76. doi: 10.1111/acel.12410. Epub 2015 Oct 8.

13.

CYR61/CCN1: A Novel Mediator of Epidermal Hyperplasia and Inflammation in Psoriasis?

Quan T, Johnston A, Gudjonsson JE, Fisher GJ.

J Invest Dermatol. 2015 Nov;135(11):2562-2564. doi: 10.1038/jid.2015.300.

14.

Dermal fibroblast expression of stromal cell-derived factor-1 (SDF-1) promotes epidermal keratinocyte proliferation in normal and diseased skin.

Quan C, Cho MK, Shao Y, Mianecki LE, Liao E, Perry D, Quan T.

Protein Cell. 2015 Dec;6(12):890-903. doi: 10.1007/s13238-015-0198-5. Epub 2015 Aug 22.

16.

A mouse model of skin aging: fragmentation of dermal collagen fibrils and reduced fibroblast spreading due to expression of human matrix metalloproteinase-1.

Xia W, Quan T, Hammerberg C, Voorhees JJ, Fisher GJ.

J Dermatol Sci. 2015 Apr;78(1):79-82. doi: 10.1016/j.jdermsci.2015.01.009. Epub 2015 Jan 28. No abstract available.

PMID:
25724359
17.

Role of Age-Associated Alterations of the Dermal Extracellular Matrix Microenvironment in Human Skin Aging: A Mini-Review.

Quan T, Fisher GJ.

Gerontology. 2015;61(5):427-34. doi: 10.1159/000371708. Epub 2015 Feb 4. Review.

18.

Oxidant exposure induces cysteine-rich protein 61 (CCN1) via c-Jun/AP-1 to reduce collagen expression in human dermal fibroblasts.

Qin Z, Robichaud P, He T, Fisher GJ, Voorhees JJ, Quan T.

PLoS One. 2014 Dec 23;9(12):e115402. doi: 10.1371/journal.pone.0115402. eCollection 2014.

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