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Items: 9

1.

Asymmetrical meta-methoxylated diarylpentanoids: Rational design, synthesis and anti-cancer evaluation in-vitro.

Leong SW, Chia SL, Abas F, Yusoff K.

Eur J Med Chem. 2018 Aug 16;157:716-728. doi: 10.1016/j.ejmech.2018.08.039. [Epub ahead of print]

PMID:
30138803
2.

Analgesic Effect of 5-(3,4-Dihydroxyphenyl)-3-hydroxy-1-(2-hydroxyphenyl)penta-2,4-dien-1-one in Experimental Animal Models of Nociception.

Kamarudin N, Hisamuddin N, Ong HM, Ahmad Azmi AF, Leong SW, Abas F, Sulaiman MR, Shaik Mossadeq WM.

Molecules. 2018 Aug 21;23(9). pii: E2099. doi: 10.3390/molecules23092099.

3.

In vitro and in silico evaluations of diarylpentanoid series as α-glucosidase inhibitor.

Leong SW, Abas F, Lam KW, Yusoff K.

Bioorg Med Chem Lett. 2017 Dec 23. pii: S0960-894X(17)31222-2. doi: 10.1016/j.bmcl.2017.12.048. [Epub ahead of print]

PMID:
29292226
4.

Erratum to: Zebrafish phenotypic screen identifies novel Notch antagonists.

Velaithan V, Okuda KS, Ng MF, Samat N, Leong SW, Faudzi SM, Abas F, Shaari K, Cheong SC, Tan PJ, Patel V.

Invest New Drugs. 2017 Apr;35(2):250. doi: 10.1007/s10637-017-0437-0. No abstract available.

PMID:
28185040
5.

Zebrafish phenotypic screen identifies novel Notch antagonists.

Velaithan V, Okuda KS, Ng MF, Samat N, Leong SW, Faudzi SM, Abas F, Shaari K, Cheong SC, Tan PJ, Patel V.

Invest New Drugs. 2017 Apr;35(2):166-179. doi: 10.1007/s10637-016-0423-y. Epub 2017 Jan 5. Erratum in: Invest New Drugs. 2017 Apr;35(2):250.

PMID:
28058624
6.

2-Benzoyl-6-benzylidenecyclohexanone analogs as potent dual inhibitors of acetylcholinesterase and butyrylcholinesterase.

Leong SW, Abas F, Lam KW, Shaari K, Lajis NH.

Bioorg Med Chem. 2016 Aug 15;24(16):3742-51. doi: 10.1016/j.bmc.2016.06.016. Epub 2016 Jun 9.

PMID:
27328658
7.

Synthesis of unsymmetrical monocarbonyl curcumin analogues with potent inhibition on prostaglandin E2 production in LPS-induced murine and human macrophages cell lines.

Mohd Aluwi MFF, Rullah K, Yamin BM, Leong SW, Abdul Bahari MN, Lim SJ, Mohd Faudzi SM, Jalil J, Abas F, Mohd Fauzi N, Ismail NH, Jantan I, Lam KW.

Bioorg Med Chem Lett. 2016 May 15;26(10):2531-2538. doi: 10.1016/j.bmcl.2016.03.092. Epub 2016 Mar 26.

PMID:
27040659
8.

Nitric oxide inhibitory activity and antioxidant evaluations of 2-benzoyl-6-benzylidenecyclohexanone analogs, a novel series of curcuminoid and diarylpentanoid derivatives.

Leong SW, Mohd Faudzi SM, Abas F, Mohd Aluwi MF, Rullah K, Lam KW, Abdul Bahari MN, Ahmad S, Tham CL, Shaari K, Lajis NH.

Bioorg Med Chem Lett. 2015 Aug 15;25(16):3330-7. doi: 10.1016/j.bmcl.2015.05.056. Epub 2015 May 30.

PMID:
26071636
9.

Synthesis and sar study of diarylpentanoid analogues as new anti-inflammatory agents.

Leong SW, Faudzi SM, Abas F, Aluwi MF, Rullah K, Wai LK, Bahari MN, Ahmad S, Tham CL, Shaari K, Lajis NH.

Molecules. 2014 Oct 9;19(10):16058-81. doi: 10.3390/molecules191016058.

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