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Items: 15


Investigating Age-Related Changes in Proliferation and the Cell Division Repertoire of Parenchymal Reactive Astrocytes.

Heimann G, Sirko S.

Methods Mol Biol. 2019;1938:277-292. doi: 10.1007/978-1-4939-9068-9_20.


Re-evaluation of neuronal P2X7 expression using novel mouse models and a P2X7-specific nanobody.

Kaczmarek-Hajek K, Zhang J, Kopp R, Grosche A, Rissiek B, Saul A, Bruzzone S, Engel T, Jooss T, Krautloher A, Schuster S, Magnus T, Stadelmann C, Sirko S, Koch-Nolte F, Eulenburg V, Nicke A.

Elife. 2018 Aug 3;7. pii: e36217. doi: 10.7554/eLife.36217.


Cross-talk between monocyte invasion and astrocyte proliferation regulates scarring in brain injury.

Frik J, Merl-Pham J, Plesnila N, Mattugini N, Kjell J, Kraska J, Gómez RM, Hauck SM, Sirko S, Götz M.

EMBO Rep. 2018 May;19(5). pii: e45294. doi: 10.15252/embr.201745294. Epub 2018 Apr 9.


Traumatic Brain Injury: At the Crossroads of Neuropathology and Common Metabolic Endocrinopathies.

Li M, Sirko S.

J Clin Med. 2018 Mar 14;7(3). pii: E59. doi: 10.3390/jcm7030059. Review.


Changes in the Proliferative Program Limit Astrocyte Homeostasis in the Aged Post-Traumatic Murine Cerebral Cortex.

Heimann G, Canhos LL, Frik J, Jäger G, Lepko T, Ninkovic J, Götz M, Sirko S.

Cereb Cortex. 2017 Aug 1;27(8):4213-4228. doi: 10.1093/cercor/bhx112.


Astrocyte reactivity after brain injury-: The role of galectins 1 and 3.

Sirko S, Irmler M, Gascón S, Bek S, Schneider S, Dimou L, Obermann J, De Souza Paiva D, Poirier F, Beckers J, Hauck SM, Barde YA, Götz M.

Glia. 2015 Dec;63(12):2340-61. doi: 10.1002/glia.22898. Epub 2015 Aug 6.


Reactive astrocytes as neural stem or progenitor cells: In vivo lineage, In vitro potential, and Genome-wide expression analysis.

Götz M, Sirko S, Beckers J, Irmler M.

Glia. 2015 Aug;63(8):1452-68. doi: 10.1002/glia.22850. Epub 2015 May 12. Review.


Reactive glia in the injured brain acquire stem cell properties in response to sonic hedgehog. [corrected].

Sirko S, Behrendt G, Johansson PA, Tripathi P, Costa M, Bek S, Heinrich C, Tiedt S, Colak D, Dichgans M, Fischer IR, Plesnila N, Staufenbiel M, Haass C, Snapyan M, Saghatelyan A, Tsai LH, Fischer A, Grobe K, Dimou L, Götz M.

Cell Stem Cell. 2013 Apr 4;12(4):426-39. doi: 10.1016/j.stem.2013.01.019. Erratum in: Cell Stem Cell. 2013 May 2;12(5):629.


Structural and functional analysis of chondroitin sulfate proteoglycans in the neural stem cell niche.

Sirko S, Akita K, Von Holst A, Faissner A.

Methods Enzymol. 2010;479:37-71. doi: 10.1016/S0076-6879(10)79003-0.


Chondroitin sulfates are required for fibroblast growth factor-2-dependent proliferation and maintenance in neural stem cells and for epidermal growth factor-dependent migration of their progeny.

Sirko S, von Holst A, Weber A, Wizenmann A, Theocharidis U, Götz M, Faissner A.

Stem Cells. 2010 Apr;28(4):775-87. doi: 10.1002/stem.309.


Focal laser-lesions activate an endogenous population of neural stem/progenitor cells in the adult visual cortex.

Sirko S, Neitz A, Mittmann T, Horvat-Bröcker A, von Holst A, Eysel UT, Faissner A.

Brain. 2009 Aug;132(Pt 8):2252-64. doi: 10.1093/brain/awp043. Epub 2009 Mar 13.


Evidence for distinct leptomeningeal cell-dependent paracrine and EGF-linked autocrine regulatory pathways for suppression of fibrillar collagens in astrocytes.

Heck N, Garwood J, Dobbertin A, Calco V, Sirko S, Mittmann T, Eysel UT, Faissner A.

Mol Cell Neurosci. 2007 Sep;36(1):71-85. Epub 2007 Jun 27.


Chondroitin sulfate glycosaminoglycans control proliferation, radial glia cell differentiation and neurogenesis in neural stem/progenitor cells.

Sirko S, von Holst A, Wizenmann A, Götz M, Faissner A.

Development. 2007 Aug;134(15):2727-38. Epub 2007 Jun 27.


Structural characterization of the epitopes of the monoclonal antibodies 473HD, CS-56, and MO-225 specific for chondroitin sulfate D-type using the oligosaccharide library.

Ito Y, Hikino M, Yajima Y, Mikami T, Sirko S, von Holst A, Faissner A, Fukui S, Sugahara K.

Glycobiology. 2005 Jun;15(6):593-603. Epub 2004 Dec 29.


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