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Items: 1 to 20 of 108


Possible Contribution of Inflammation-Associated Hypoxia to Increased K2P5.1 K+ Channel Expression in CD4+ T cells of the Mouse Model for Inflammatory Bowel Disease.

Endo K, Kito H, Tanaka R, Kajikuri J, Tanaka S, Elboray EE, Suzuki T, Ohya S.

Int J Mol Sci. 2019 Dec 19;21(1). pii: E38. doi: 10.3390/ijms21010038.


[Ca2+-activated K+ channels as cancer therapeutic targets].

Ohya S, Kito H, Kajikuri J.

Nihon Yakurigaku Zasshi. 2019;154(3):108-113. doi: 10.1254/fpj.154.108. Japanese.


Castration Induces Down-Regulation of A-Type K+ Channel in Rat Vas Deferens Smooth Muscle.

Ohya S, Ito K, Hatano N, Ohno A, Muraki K, Imaizumi Y.

Int J Mol Sci. 2019 Aug 21;20(17). pii: E4073. doi: 10.3390/ijms20174073.


Brain allopregnanolone induces marked scratching behaviour in diet-induced atopic dermatitis mouse model.

Fujii M, Ohgami S, Asano E, Nakayama T, Toda T, Nabe T, Ohya S.

Sci Rep. 2019 Feb 20;9(1):2364. doi: 10.1038/s41598-019-38858-3.


Conversion of Ca2+ oscillation into propagative electrical signals by Ca2+-activated ion channels and connexin as a reconstituted Ca2+ clock model for the pacemaker activity.

Saeki T, Kimura T, Hashidume K, Murayama T, Yamamura H, Ohya S, Suzuki Y, Nakayama S, Imaizumi Y.

Biochem Biophys Res Commun. 2019 Mar 5;510(2):242-247. doi: 10.1016/j.bbrc.2019.01.080. Epub 2019 Jan 24.


Inhibition of Interleukin 10 Transcription through the SMAD2/3 Signaling Pathway by Ca2+-Activated K+ Channel KCa3.1 Activation in Human T-Cell Lymphoma HuT-78 Cells.

Matsui M, Kajikuri J, Kito H, Endo K, Hasegawa Y, Murate S, Ohya S.

Mol Pharmacol. 2019 Mar;95(3):294-302. doi: 10.1124/mol.118.114405. Epub 2019 Jan 8.


Histone Deacetylases Enhance Ca2+-Activated K⁺ Channel KCa3.1 Expression in Murine Inflammatory CD4⁺ T Cells.

Matsui M, Terasawa K, Kajikuri J, Kito H, Endo K, Jaikhan P, Suzuki T, Ohya S.

Int J Mol Sci. 2018 Sep 27;19(10). pii: E2942. doi: 10.3390/ijms19102942.


Barbiturates enhance itch-associated scratching in atopic dermatitis mice: A possible clue to understanding nocturnal pruritus in atopic dermatitis.

Fujii M, Takeuchi K, Umehara Y, Takeuchi M, Nakayama T, Ohgami S, Asano E, Nabe T, Ohya S.

Eur J Pharmacol. 2018 Oct 5;836:57-66. doi: 10.1016/j.ejphar.2018.08.018. Epub 2018 Aug 18.


Ca2+-Activated K+ Channel KCa3.1 as a Therapeutic Target for Immune Disorders.

Ohya S, Kito H.

Biol Pharm Bull. 2018;41(8):1158-1163. doi: 10.1248/bpb.b18-00078. Review.



Ohya S.

Biol Pharm Bull. 2018;41(8):1126. doi: 10.1248/bpb.b18-ctf4108. No abstract available.


Transcriptional repression of human epidermal growth factor receptor 2 by ClC-3 Cl- /H+ transporter inhibition in human breast cancer cells.

Fujimoto M, Kito H, Kajikuri J, Ohya S.

Cancer Sci. 2018 Sep;109(9):2781-2791. doi: 10.1111/cas.13715. Epub 2018 Jul 28.


Transcriptional Repression and Protein Degradation of the Ca2+-Activated K+ Channel KCa1.1 by Androgen Receptor Inhibition in Human Breast Cancer Cells.

Khatun A, Shimozawa M, Kito H, Kawaguchi M, Fujimoto M, Ri M, Kajikuri J, Niwa S, Fujii M, Ohya S.

Front Physiol. 2018 Apr 16;9:312. doi: 10.3389/fphys.2018.00312. eCollection 2018.


Negative regulation of cellular Ca2+ mobilization by ryanodine receptor type 3 in mouse mesenteric artery smooth muscle.

Matsuki K, Kato D, Takemoto M, Suzuki Y, Yamamura H, Ohya S, Takeshima H, Imaizumi Y.

Am J Physiol Cell Physiol. 2018 Jul 1;315(1):C1-C9. doi: 10.1152/ajpcell.00006.2018. Epub 2018 Mar 14.


ATP increases [Ca2+ ]i and activates a Ca2+ -dependent Cl- current in rat ventricular fibroblasts.

Hatano N, Ohya S, Imaizumi Y, Clark RB, Belke D, Giles WR.

Exp Physiol. 2018 May 1;103(5):666-682. doi: 10.1113/EP086822. Epub 2018 Apr 15.


Eicosapentaenoic acid ethyl ester ameliorates atopic dermatitis-like symptoms in special diet-fed hairless mice, partly by restoring covalently bound ceramides in the stratum corneum.

Fujii M, Ohyanagi C, Kawaguchi N, Matsuda H, Miyamoto Y, Ohya S, Nabe T.

Exp Dermatol. 2018 Aug;27(8):837-840. doi: 10.1111/exd.13507. Epub 2018 Apr 6.


Up-Regulation of the Voltage-Gated KV2.1 K+ Channel in the Renal Arterial Myocytes of Dahl Salt-Sensitive Hypertensive Rats.

Ogiwara K, Ohya S, Suzuki Y, Yamamura H, Imaizumi Y.

Biol Pharm Bull. 2017;40(9):1468-1474. doi: 10.1248/bpb.b17-00289.


Proliferative Role of Kv11 Channels in Murine Arteries.

Barrese V, Cidad P, Yeung SY, López-López JR, McNeish AJ, Ohya S, Pérez-García MT, Greenwood IA.

Front Physiol. 2017 Jul 12;8:500. doi: 10.3389/fphys.2017.00500. eCollection 2017.


Molecular mechanisms underlying pimaric acid-induced modulation of voltage-gated K+ channels.

Sakamoto K, Suzuki Y, Yamamura H, Ohya S, Muraki K, Imaizumi Y.

J Pharmacol Sci. 2017 Apr;133(4):223-231. doi: 10.1016/j.jphs.2017.02.013. Epub 2017 Mar 8.


Down-Regulation of Ca2+-Activated K⁺ Channel KCa1.1 in Human Breast Cancer MDA-MB-453 Cells Treated with Vitamin D Receptor Agonists.

Khatun A, Fujimoto M, Kito H, Niwa S, Suzuki T, Ohya S.

Int J Mol Sci. 2016 Dec 11;17(12). pii: E2083.


Ryanodine receptor type 3 does not contribute to contractions in the mouse myometrium regardless of pregnancy.

Matsuki K, Takemoto M, Suzuki Y, Yamamura H, Ohya S, Takeshima H, Imaizumi Y.

Pflugers Arch. 2017 Feb;469(2):313-326. doi: 10.1007/s00424-016-1900-z. Epub 2016 Nov 20.


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