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Items: 1 to 20 of 63


A humanized bone microenvironment uncovers HIF2 alpha as a latent marker for osteosarcoma.

Wagner F, Holzapfel BM, Martine LC, McGovern J, Lahr CA, Boxberg M, Prodinger PM, Grässel S, Loessner D, Hutmacher DW.

Acta Biomater. 2019 Apr 15;89:372-381. doi: 10.1016/j.actbio.2019.02.051. Epub 2019 Mar 2.


Impact of Mechanical Load on the Expression Profile of Synovial Fibroblasts from Patients with and without Osteoarthritis.

Schröder A, Nazet U, Muschter D, Grässel S, Proff P, Kirschneck C.

Int J Mol Sci. 2019 Jan 30;20(3). pii: E585. doi: 10.3390/ijms20030585.


Sensory Neuropeptides and their Receptors Participate in Mechano-Regulation of Murine Macrophages.

Muschter D, Beiderbeck AS, Späth T, Kirschneck C, Schröder A, Grässel S.

Int J Mol Sci. 2019 Jan 24;20(3). pii: E503. doi: 10.3390/ijms20030503.


Kooperation der DGOU mit der ORS.

Grässel S, Windolf J, Siebert WE, Nerlich M, Loibl M.

Z Orthop Unfall. 2018 Oct;156(5):493-495. doi: 10.1055/a-0659-4729. Epub 2018 Oct 5. German. No abstract available.


Substance P modulates bone remodeling properties of murine osteoblasts and osteoclasts.

Niedermair T, Schirner S, Seebröker R, Straub RH, Grässel S.

Sci Rep. 2018 Jun 15;8(1):9199. doi: 10.1038/s41598-018-27432-y.


Do Neuroendocrine Peptides and Their Receptors Qualify as Novel Therapeutic Targets in Osteoarthritis?

Grässel S, Muschter D.

Int J Mol Sci. 2018 Jan 26;19(2). pii: E367. doi: 10.3390/ijms19020367. Review.


[Cooperation of the German Society of Orthopaedics and Trauma (DGOU) and the Orthopaedic Research Society (ORS)].

Hildebrand F, Grässel S, Marzi I, Meurer A, Nerlich M, Loibl M.

Z Orthop Unfall. 2017 Oct;155(5):515-516. doi: 10.1055/s-0043-116849. Epub 2017 Oct 19. German. No abstract available.


miR-29b regulates expression of collagens I and III in chondrogenically differentiating BMSC in an osteoarthritic environment.

Mayer U, Benditz A, Grässel S.

Sci Rep. 2017 Oct 16;7(1):13297. doi: 10.1038/s41598-017-13567-x.


Peripheral Nerve Fibers and Their Neurotransmitters in Osteoarthritis Pathology.

Grässel S, Muschter D.

Int J Mol Sci. 2017 Apr 28;18(5). pii: E931. doi: 10.3390/ijms18050931. Review.


α-MSH modulates cell adhesion and inflammatory responses of synovial fibroblasts from osteoarthritis patients.

Böhm M, Apel M, Lowin T, Lorenz J, Jenei-Lanzl Z, Capellino S, Dosoki H, Luger TA, Straub RH, Grässel S.

Biochem Pharmacol. 2016 Sep 15;116:89-99. doi: 10.1016/j.bcp.2016.07.003. Epub 2016 Jul 7.


The impact of hypoxia on mesenchymal progenitor cells of human skeletal tissue in the pathogenesis of heterotopic ossification.

Winkler S, Niedermair T, Füchtmeier B, Grifka J, Grässel S, Anders S, Heers G, Wagner F.

Int Orthop. 2015 Dec;39(12):2495-501. doi: 10.1007/s00264-015-2995-0. Epub 2015 Oct 3.


Sympathetic Neurotransmitters Modulate Osteoclastogenesis and Osteoclast Activity in the Context of Collagen-Induced Arthritis.

Muschter D, Schäfer N, Stangl H, Straub RH, Grässel S.

PLoS One. 2015 Oct 2;10(10):e0139726. doi: 10.1371/journal.pone.0139726. eCollection 2015.


The NC11 domain of human collagen XVI induces vasculogenic mimicry in oral squamous cell carcinoma cells.

Bedal KB, Grässel S, Spanier G, Reichert TE, Bauer RJ.

Carcinogenesis. 2015 Nov;36(11):1429-39. doi: 10.1093/carcin/bgv141. Epub 2015 Sep 30.


Reactivity of rat bone marrow-derived macrophages to neurotransmitter stimulation in the context of collagen II-induced arthritis.

Muschter D, Göttl C, Vogel M, Grifka J, Straub RH, Grässel S.

Arthritis Res Ther. 2015 Jun 24;17:169. doi: 10.1186/s13075-015-0684-4.


Catecholaminergic-to-cholinergic transition of sympathetic nerve fibers is stimulated under healthy but not under inflammatory arthritic conditions.

Stangl H, Springorum HR, Muschter D, Grässel S, Straub RH.

Brain Behav Immun. 2015 May;46:180-91. doi: 10.1016/j.bbi.2015.02.022. Epub 2015 Feb 28.


Subchondral bone influences chondrogenic differentiation and collagen production of human bone marrow-derived mesenchymal stem cells and articular chondrocytes.

Leyh M, Seitz A, Dürselen L, Schaumburger J, Ignatius A, Grifka J, Grässel S.

Arthritis Res Ther. 2014 Oct 7;16(5):453. doi: 10.1186/s13075-014-0453-9.


Melanocortin 1 receptor-signaling deficiency results in an articular cartilage phenotype and accelerates pathogenesis of surgically induced murine osteoarthritis.

Lorenz J, Seebach E, Hackmayer G, Greth C, Bauer RJ, Kleinschmidt K, Bettenworth D, Böhm M, Grifka J, Grässel S.

PLoS One. 2014 Sep 5;9(9):e105858. doi: 10.1371/journal.pone.0105858. eCollection 2014.


Tissue-engineering strategies to repair chondral and osteochondral tissue in osteoarthritis: use of mesenchymal stem cells.

Grässel S, Lorenz J.

Curr Rheumatol Rep. 2014 Oct;16(10):452. doi: 10.1007/s11926-014-0452-5. Review.


Experimental osteoarthritis models in mice.

Lorenz J, Grässel S.

Methods Mol Biol. 2014;1194:401-19. doi: 10.1007/978-1-4939-1215-5_23.


Absence of substance P and the sympathetic nervous system impact on bone structure and chondrocyte differentiation in an adult model of endochondral ossification.

Niedermair T, Kuhn V, Doranehgard F, Stange R, Wieskötter B, Beckmann J, Salmen P, Springorum HR, Straub RH, Zimmer A, Grifka J, Grässel S.

Matrix Biol. 2014 Sep;38:22-35. doi: 10.1016/j.matbio.2014.06.007. Epub 2014 Jul 22.

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