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Items: 1 to 20 of 21

1.

The Membrane-Active Phytopeptide Cycloviolacin O2 Simultaneously Targets HIV-1-infected Cells and Infectious Viral Particles to Potentiate the Efficacy of Antiretroviral Drugs.

Gerlach SL, Chandra PK, Roy U, Gunasekera S, Göransson U, Wimley WC, Braun SE, Mondal D.

Medicines (Basel). 2019 Feb 28;6(1). pii: E33. doi: 10.3390/medicines6010033.

2.

Demosponge steroid biomarker 26-methylstigmastane provides evidence for Neoproterozoic animals.

Zumberge JA, Love GD, Cárdenas P, Sperling EA, Gunasekera S, Rohrssen M, Grosjean E, Grotzinger JP, Summons RE.

Nat Ecol Evol. 2018 Nov;2(11):1709-1714. doi: 10.1038/s41559-018-0676-2. Epub 2018 Oct 15.

PMID:
30323207
3.

Stabilized Cyclic Peptides as Scavengers of Autoantibodies: Neutralization of Anticitrullinated Protein/Peptide Antibodies in Rheumatoid Arthritis.

Gunasekera S, Fernandes-Cerqueira C, Wennmalm S, Wähämaa H, Sommarin Y, Catrina AI, Jakobsson PJ, Göransson U.

ACS Chem Biol. 2018 Jun 15;13(6):1525-1535. doi: 10.1021/acschembio.8b00118. Epub 2018 May 24.

PMID:
29630823
4.

Alanine and Lysine Scans of the LL-37-Derived Peptide Fragment KR-12 Reveal Key Residues for Antimicrobial Activity.

Gunasekera S, Muhammad T, Strömstedt AA, Rosengren KJ, Göransson U.

Chembiochem. 2018 May 4;19(9):931-939. doi: 10.1002/cbic.201700599. Epub 2018 Mar 30.

PMID:
29430821
5.

Chemical Proteomics for Target Discovery of Head-to-Tail Cyclized Mini-Proteins.

Hellinger R, Thell K, Vasileva M, Muhammad T, Gunasekera S, Kümmel D, Göransson U, Becker CW, Gruber CW.

Front Chem. 2017 Oct 11;5:73. doi: 10.3389/fchem.2017.00073. eCollection 2017.

6.

The N-terminal pro-domain of the kalata B1 cyclotide precursor is intrinsically unstructured.

Daly NL, Gunasekera S, Clark RJ, Lin F, Wade JD, Anderson MA, Craik DJ.

Biopolymers. 2016 Nov;106(6):825-833. doi: 10.1002/bip.22977.

PMID:
27564841
7.

Selective membrane disruption by the cyclotide kalata B7: complex ions and essential functional groups in the phosphatidylethanolamine binding pocket.

Strömstedt AA, Kristiansen PE, Gunasekera S, Grob N, Skjeldal L, Göransson U.

Biochim Biophys Acta. 2016 Jun;1858(6):1317-27. doi: 10.1016/j.bbamem.2016.02.013. Epub 2016 Feb 12.

8.

Synthesis, Structural Characterization, and Bioactivity of the Stable Peptide RCB-1 from Ricinus communis.

Boldbaatar D, Gunasekera S, El-Seedi HR, Göransson U.

J Nat Prod. 2015 Nov 25;78(11):2545-51. doi: 10.1021/acs.jnatprod.5b00463. Epub 2015 Oct 28.

PMID:
26509914
9.

Isolation, Characterization, and Synthesis of the Barrettides: Disulfide-Containing Peptides from the Marine Sponge Geodia barretti.

Carstens BB, Rosengren KJ, Gunasekera S, Schempp S, Bohlin L, Dahlström M, Clark RJ, Göransson U.

J Nat Prod. 2015 Aug 28;78(8):1886-93. doi: 10.1021/acs.jnatprod.5b00210. Epub 2015 Jul 29.

PMID:
26222779
10.

Targeting of anti-citrullinated protein/peptide antibodies in rheumatoid arthritis using peptides mimicking endogenously citrullinated fibrinogen antigens.

Fernandes-Cerqueira C, Ossipova E, Gunasekera S, Hansson M, Mathsson L, Catrina AI, Sommarin Y, Klareskog L, Lundberg K, Rönnelid J, Göransson U, Jakobsson PJ.

Arthritis Res Ther. 2015 Jun 10;17:155. doi: 10.1186/s13075-015-0666-6.

11.

A cactus-derived toxin-like cystine knot Peptide with selective antimicrobial activity.

Aboye TL, Strömstedt AA, Gunasekera S, Bruhn JG, El-Seedi H, Rosengren KJ, Göransson U.

Chembiochem. 2015 May 4;16(7):1068-77. doi: 10.1002/cbic.201402704. Epub 2015 Mar 27.

PMID:
25821084
12.

Chemistry and biology of cyclotides: circular plant peptides outside the box.

Burman R, Gunasekera S, Strömstedt AA, Göransson U.

J Nat Prod. 2014 Mar 28;77(3):724-36. doi: 10.1021/np401055j. Epub 2014 Feb 14. Review.

PMID:
24527877
13.

Oxytocic plant cyclotides as templates for peptide G protein-coupled receptor ligand design.

Koehbach J, O'Brien M, Muttenthaler M, Miazzo M, Akcan M, Elliott AG, Daly NL, Harvey PJ, Arrowsmith S, Gunasekera S, Smith TJ, Wray S, Göransson U, Dawson PE, Craik DJ, Freissmuth M, Gruber CW.

Proc Natl Acad Sci U S A. 2013 Dec 24;110(52):21183-8. doi: 10.1073/pnas.1311183110. Epub 2013 Nov 18.

14.

Making Ends Meet: Microwave-Accelerated Synthesis of Cyclic and Disulfide Rich Proteins Via In Situ Thioesterification and Native Chemical Ligation.

Gunasekera S, Aboye TL, Madian WA, El-Seedi HR, Göransson U.

Int J Pept Res Ther. 2013 Mar;19(1):43-54. Epub 2012 Oct 14.

15.

Circular proteins from plants and fungi.

Göransson U, Burman R, Gunasekera S, Strömstedt AA, Rosengren KJ.

J Biol Chem. 2012 Aug 3;287(32):27001-6. doi: 10.1074/jbc.R111.300129. Epub 2012 Jun 14. Review.

16.

Engineering pro-angiogenic peptides using stable, disulfide-rich cyclic scaffolds.

Chan LY, Gunasekera S, Henriques ST, Worth NF, Le SJ, Clark RJ, Campbell JH, Craik DJ, Daly NL.

Blood. 2011 Dec 15;118(25):6709-17. doi: 10.1182/blood-2011-06-359141. Epub 2011 Oct 28.

17.

Stabilization of α-conotoxin AuIB: influences of disulfide connectivity and backbone cyclization.

Lovelace ES, Gunasekera S, Alvarmo C, Clark RJ, Nevin ST, Grishin AA, Adams DJ, Craik DJ, Daly NL.

Antioxid Redox Signal. 2011 Jan 1;14(1):87-95. doi: 10.1089/ars.2009.3068. Epub 2010 Aug 20.

PMID:
20486767
18.

Engineering stabilized vascular endothelial growth factor-A antagonists: synthesis, structural characterization, and bioactivity of grafted analogues of cyclotides.

Gunasekera S, Foley FM, Clark RJ, Sando L, Fabri LJ, Craik DJ, Daly NL.

J Med Chem. 2008 Dec 25;51(24):7697-704. doi: 10.1021/jm800704e.

PMID:
19053834
19.

Dissecting the oxidative folding of circular cystine knot miniproteins.

Gunasekera S, Daly NL, Clark RJ, Craik DJ.

Antioxid Redox Signal. 2009 May;11(5):971-80. doi: 10.1089/ARS.2008.2295.

PMID:
19025420
20.

Mechanism of action of cytotoxic cyclotides: cycloviolacin O2 disrupts lipid membranes.

Svangård E, Burman R, Gunasekera S, Lövborg H, Gullbo J, Göransson U.

J Nat Prod. 2007 Apr;70(4):643-7. Epub 2007 Mar 23.

PMID:
17378610

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