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Items: 2

1.

Type II DNA Topoisomerases Cause Spontaneous Double-Strand Breaks in Genomic DNA.

Morimoto S, Tsuda M, Bunch H, Sasanuma H, Austin C, Takeda S.

Genes (Basel). 2019 Oct 30;10(11). pii: E868. doi: 10.3390/genes10110868. Review.

2.

BRCA1 ensures genome integrity by eliminating estrogen-induced pathological topoisomerase II-DNA complexes.

Sasanuma H, Tsuda M, Morimoto S, Saha LK, Rahman MM, Kiyooka Y, Fujiike H, Cherniack AD, Itou J, Callen Moreu E, Toi M, Nakada S, Tanaka H, Tsutsui K, Yamada S, Nussenzweig A, Takeda S.

Proc Natl Acad Sci U S A. 2018 Nov 6;115(45):E10642-E10651. doi: 10.1073/pnas.1803177115. Epub 2018 Oct 23.

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