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Items: 1 to 20 of 37


Improving Estrogenic Compound Screening Efficiency by Using Self-Modulating, Continuously Bioluminescent Human Cell Bioreporters Expressing a Synthetic Luciferase.

Xu T, Kirkpatrick A, Toperzer J, Ripp S, Close D.

Toxicol Sci. 2019 Apr 1;168(2):551-560. doi: 10.1093/toxsci/kfz004.


A rapid and reagent-free bioassay for the detection of dioxin-like compounds and other aryl hydrocarbon receptor (AhR) agonists using autobioluminescent yeast.

Xu T, Young A, Marr E, Sayler G, Ripp S, Close D.

Anal Bioanal Chem. 2018 Feb;410(4):1247-1256. doi: 10.1007/s00216-017-0780-1. Epub 2017 Dec 6.


Co-Cultured Continuously Bioluminescent Human Cells as Bioreporters for the Detection of Prodrug Therapeutic Impact Pre- and Post-Metabolism.

Xu T, Conway M, Frank A, Ripp S, Sayler G, Close D.

Sensors (Basel). 2017 Dec 6;17(12). pii: E2827. doi: 10.3390/s17122827.


The Expanding Toolbox of In Vivo Bioluminescent Imaging.

Xu T, Close D, Handagama W, Marr E, Sayler G, Ripp S.

Front Oncol. 2016 Jun 23;6:150. doi: 10.3389/fonc.2016.00150. eCollection 2016. Review.


A Real-Time Non-invasive Auto-bioluminescent Urinary Bladder Cancer Xenograft Model.

John BA, Xu T, Ripp S, Wang HR.

Mol Imaging Biol. 2017 Feb;19(1):10-14. doi: 10.1007/s11307-016-0989-y.


The Repetitive Detection of Toluene with Bioluminescence Bioreporter Pseudomonas putida TVA8 Encapsulated in Silica Hydrogel on an Optical Fiber.

Kuncová G, Ishizaki T, Solovyev A, Trögl J, Ripp S.

Materials (Basel). 2016 Jun 15;9(6). pii: E467. doi: 10.3390/ma9060467.


Real-time toxicity and metabolic activity tracking of human cells exposed to Escherichia coli O157:H7 in a mixed consortia.

Xu T, Marr E, Lam H, Ripp S, Sayler G, Close D.

Ecotoxicology. 2015 Dec;24(10):2133-40. doi: 10.1007/s10646-015-1552-3. Epub 2015 Sep 30.


Biological toxicity of cellulose nanocrystals (CNCs) against the luxCDABE-based bioluminescent bioreporter Escherichia coli 652T7.

Du L, Arnholt K, Ripp S, Sayler G, Wang S, Liang C, Wang J, Zhuang J.

Ecotoxicology. 2015 Dec;24(10):2049-53. doi: 10.1007/s10646-015-1555-0. Epub 2015 Sep 29.


Microbial availability of mercury: effective detection and organic ligand effect using a whole-cell bioluminescent bioreporter.

Xu X, Oliff K, Xu T, Ripp S, Sayler G, Zhuang J.

Ecotoxicology. 2015 Dec;24(10):2200-6. doi: 10.1007/s10646-015-1553-2. Epub 2015 Sep 29.


Detection of organic compounds with whole-cell bioluminescent bioassays.

Xu T, Close D, Smartt A, Ripp S, Sayler G.

Adv Biochem Eng Biotechnol. 2014;144:111-51. doi: 10.1007/978-3-662-43385-0_4. Review.


Expression of a humanized viral 2A-mediated lux operon efficiently generates autonomous bioluminescence in human cells.

Xu T, Ripp S, Sayler GS, Close DM.

PLoS One. 2014 May 2;9(5):e96347. doi: 10.1371/journal.pone.0096347. eCollection 2014.


Autonomously bioluminescent mammalian cells for continuous and real-time monitoring of cytotoxicity.

Xu T, Close DM, Webb JD, Ripp SA, Sayler GS.

J Vis Exp. 2013 Oct 28;(80):e50972. doi: 10.3791/50972.


Real-time bioluminescent tracking of cellular population dynamics.

Close D, Xu T, Ripp S, Sayler G.

Methods Mol Biol. 2014;1098:107-16. doi: 10.1007/978-1-62703-718-1_9.


C60 reduces the bioavailability of mercury in aqueous solutions.

Shi WJ, Menn FM, Xu T, Zhuang ZT, Beasley C, Ripp S, Zhuang J, Layton AC, Sayler GS.

Chemosphere. 2014 Jan;95:324-8. doi: 10.1016/j.chemosphere.2013.09.027. Epub 2013 Oct 11.


Continuous, real-time bioimaging of chemical bioavailability and toxicology using autonomously bioluminescent human cell lines.

Xu T, Close DM, Webb JD, Price SL, Ripp SA, Sayler GS.

Proc SPIE Int Soc Opt Eng. 2013 May 29;8723:872310.


Genetically modified whole-cell bioreporters for environmental assessment.

Xu T, Close DM, Sayler GS, Ripp S.

Ecol Indic. 2013 May 1;28:125-141.


Pseudomonas fluorescens HK44: lessons learned from a model whole-cell bioreporter with a broad application history.

Trögl J, Chauhan A, Ripp S, Layton AC, Kuncová G, Sayler GS.

Sensors (Basel). 2012;12(2):1544-71. doi: 10.3390/s120201544. Epub 2012 Feb 6. Review.


The evolution of the bacterial luciferase gene cassette (lux) as a real-time bioreporter.

Close D, Xu T, Smartt A, Rogers A, Crossley R, Price S, Ripp S, Sayler G.

Sensors (Basel). 2012;12(1):732-52. doi: 10.3390/s120100732. Epub 2012 Jan 11. Review.


In vivo bioluminescent imaging (BLI): noninvasive visualization and interrogation of biological processes in living animals.

Close DM, Xu T, Sayler GS, Ripp S.

Sensors (Basel). 2011;11(1):180-206. doi: 10.3390/s110100180. Epub 2010 Dec 28. Review.


Silicon photomultiplier (SPM) detection of low-level bioluminescence for the development of deployable whole-cell biosensors: possibilities and limitations.

Li H, Lopes N, Moser S, Sayler G, Ripp S.

Biosens Bioelectron. 2012 Mar 15;33(1):299-303. doi: 10.1016/j.bios.2012.01.008. Epub 2012 Jan 16.

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