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Items: 1 to 20 of 72

1.

Neuropathological Correlates of Cumulative Benzodiazepine and Anticholinergic Drug Use.

Richardson K, Wharton SB, Grossi CM, Matthews FE, Fox C, Maidment I, Loke YK, Steel N, Arthur A, Myint PK, Boustani M, Campbell N, Robinson L, Brayne C, Savva GM.

J Alzheimers Dis. 2020 Feb 27. doi: 10.3233/JAD-191199. [Epub ahead of print]

2.

The Pattern of AQP4 Expression in the Ageing Human Brain and in Cerebral Amyloid Angiopathy.

Owasil R, O'Neill R, Keable A, Nimmo J, MacGregor Sharp M, Kelly L, Saito S, Simpson JE, Weller RO, Smith C, Attems J, Wharton SB, Yuen HM, Carare RO.

Int J Mol Sci. 2020 Feb 12;21(4). pii: E1225. doi: 10.3390/ijms21041225.

3.

NDRG2 Expression Correlates with Neurofibrillary Tangles and Microglial Pathology in the Ageing Brain.

Fadul MM, Garwood CJ, Waller R, Garrett N, Heath PR, Matthews FE, Brayne C, Wharton SB, Simpson JE.

Int J Mol Sci. 2020 Jan 4;21(1). pii: E340. doi: 10.3390/ijms21010340.

4.

Neutrophil-Derived Microvesicle Induced Dysfunction of Brain Microvascular Endothelial Cells In Vitro.

Ajikumar A, Long MB, Heath PR, Wharton SB, Ince PG, Ridger VC, Simpson JE.

Int J Mol Sci. 2019 Oct 22;20(20). pii: E5227. doi: 10.3390/ijms20205227.

5.

Age-Associated mRNA and miRNA Expression Changes in the Blood-Brain Barrier.

Goodall EF, Leach V, Wang C, Cooper-Knock J, Heath PR, Baker D, Drew DR, Saffrey MJ, Simpson JE, Romero IA, Wharton SB.

Int J Mol Sci. 2019 Jun 25;20(12). pii: E3097. doi: 10.3390/ijms20123097.

6.

The Time Course of Recognition Memory Impairment and Glial Pathology in the hAPP-J20 Mouse Model of Alzheimer's Disease.

Ameen-Ali KE, Simpson JE, Wharton SB, Heath PR, Sharp PS, Brezzo G, Berwick J.

J Alzheimers Dis. 2019;68(2):609-624. doi: 10.3233/JAD-181238.

PMID:
30814360
7.

Pituitary apoplexy secondary to metastatic breast carcinoma into a gonadotroph cell adenoma of the pituitary.

Mills MT, Wharton SB, Connolly DJ, Mirza S, Sinha S.

Br J Neurosurg. 2018 Nov 26:1-4. doi: 10.1080/02688697.2018.1540766. [Epub ahead of print]

PMID:
30475069
8.

Metallothionein-I/II expression associates with the astrocyte DNA damage response and not Alzheimer-type pathology in the aging brain.

Waller R, Murphy M, Garwood CJ, Jennings L, Heath PR, Chambers A, Matthews FE, Brayne C, Ince PG, Wharton SB, Simpson JE; Cognitive Function and Ageing Neuropathology Study Group.

Glia. 2018 Nov;66(11):2316-2323. doi: 10.1002/glia.23465. Epub 2018 Aug 10.

PMID:
30098078
9.

Loss of IGF1R in Human Astrocytes Alters Complex I Activity and Support for Neurons.

Ratcliffe LE, Vázquez Villaseñor I, Jennings L, Heath PR, Mortiboys H, Schwartzentruber A, Karyka E, Simpson JE, Ince PG, Garwood CJ, Wharton SB.

Neuroscience. 2018 Oct 15;390:46-59. doi: 10.1016/j.neuroscience.2018.07.029. Epub 2018 Jul 27.

10.

Proteomic and cellular localisation studies suggest non-tight junction cytoplasmic and nuclear roles for occludin in astrocytes.

Morgan SV, Garwood CJ, Jennings L, Simpson JE, Castelli LM, Heath PR, Mihaylov SR, Vaquéz-Villaseñor I, Minshull TC, Ince PG, Dickman MJ, Hautbergue GM, Wharton SB.

Eur J Neurosci. 2018 Jun;47(12):1444-1456. doi: 10.1111/ejn.13933. Epub 2018 May 30.

11.

Immuno-Laser-Capture Microdissection for the Isolation of Enriched Glial Populations from Frozen Post-Mortem Human Brain.

Simpson JE, Wharton SB, Heath PR.

Methods Mol Biol. 2018;1723:273-284. doi: 10.1007/978-1-4939-7558-7_16.

PMID:
29344867
12.

Multisite Assessment of Aging-Related Tau Astrogliopathy (ARTAG).

Kovacs GG, Xie SX, Lee EB, Robinson JL, Caswell C, Irwin DJ, Toledo JB, Johnson VE, Smith DH, Alafuzoff I, Attems J, Bencze J, Bieniek KF, Bigio EH, Bodi I, Budka H, Dickson DW, Dugger BN, Duyckaerts C, Ferrer I, Forrest SL, Gelpi E, Gentleman SM, Giaccone G, Grinberg LT, Halliday GM, Hatanpaa KJ, Hof PR, Hofer M, Hortobágyi T, Ironside JW, King A, Kofler J, Kövari E, Kril JJ, Love S, Mackenzie IR, Mao Q, Matej R, McLean C, Munoz DG, Murray ME, Neltner J, Nelson PT, Ritchie D, Rodriguez RD, Rohan Z, Rozemuller A, Sakai K, Schultz C, Seilhean D, Smith V, Tacik P, Takahashi H, Takao M, Rudolf Thal D, Weis S, Wharton SB, White CL 3rd, Woulfe JM, Yamada M, Trojanowski JQ.

J Neuropathol Exp Neurol. 2017 Jul 1;76(7):605-619. doi: 10.1093/jnen/nlx041.

13.

Novel molecular subgroups for clinical classification and outcome prediction in childhood medulloblastoma: a cohort study.

Schwalbe EC, Lindsey JC, Nakjang S, Crosier S, Smith AJ, Hicks D, Rafiee G, Hill RM, Iliasova A, Stone T, Pizer B, Michalski A, Joshi A, Wharton SB, Jacques TS, Bailey S, Williamson D, Clifford SC.

Lancet Oncol. 2017 Jul;18(7):958-971. doi: 10.1016/S1470-2045(17)30243-7. Epub 2017 May 22.

14.

Intracerebral Masson's Tumor-Slow-Filling Vascular Lesion Demonstrated by Indocyanine Green Video Angiography.

Bagga V, Kailaya-Vasan A, Wharton SB, Patel U.

World Neurosurg. 2017 May;101:812.e15-812.e19. doi: 10.1016/j.wneu.2017.03.075. Epub 2017 Mar 25.

15.

Gene expression profiling of the astrocyte transcriptome in multiple sclerosis normal appearing white matter reveals a neuroprotective role.

Waller R, Woodroofe MN, Wharton SB, Ince PG, Francese S, Heath PR, Cudzich-Madry A, Thomas RH, Rounding N, Sharrack B, Simpson JE.

J Neuroimmunol. 2016 Oct 15;299:139-146. doi: 10.1016/j.jneuroim.2016.09.010. Epub 2016 Sep 14.

16.

Post-mortem assessment in vascular dementia: advances and aspirations.

McAleese KE, Alafuzoff I, Charidimou A, De Reuck J, Grinberg LT, Hainsworth AH, Hortobagyi T, Ince P, Jellinger K, Gao J, Kalaria RN, Kovacs GG, Kövari E, Love S, Popovic M, Skrobot O, Taipa R, Thal DR, Werring D, Wharton SB, Attems J.

BMC Med. 2016 Aug 26;14(1):129. doi: 10.1186/s12916-016-0676-5. Review.

17.

Epidemiological pathology of Tau in the ageing brain: application of staging for neuropil threads (BrainNet Europe protocol) to the MRC cognitive function and ageing brain study.

Wharton SB, Minett T, Drew D, Forster G, Matthews F, Brayne C, Ince PG; MRC Cognitive Function and Ageing Neuropathology Study Group.

Acta Neuropathol Commun. 2016 Feb 8;4:11. doi: 10.1186/s40478-016-0275-x.

18.

Aging-related tau astrogliopathy (ARTAG): harmonized evaluation strategy.

Kovacs GG, Ferrer I, Grinberg LT, Alafuzoff I, Attems J, Budka H, Cairns NJ, Crary JF, Duyckaerts C, Ghetti B, Halliday GM, Ironside JW, Love S, Mackenzie IR, Munoz DG, Murray ME, Nelson PT, Takahashi H, Trojanowski JQ, Ansorge O, Arzberger T, Baborie A, Beach TG, Bieniek KF, Bigio EH, Bodi I, Dugger BN, Feany M, Gelpi E, Gentleman SM, Giaccone G, Hatanpaa KJ, Heale R, Hof PR, Hofer M, Hortobágyi T, Jellinger K, Jicha GA, Ince P, Kofler J, Kövari E, Kril JJ, Mann DM, Matej R, McKee AC, McLean C, Milenkovic I, Montine TJ, Murayama S, Lee EB, Rahimi J, Rodriguez RD, Rozemüller A, Schneider JA, Schultz C, Seeley W, Seilhean D, Smith C, Tagliavini F, Takao M, Thal DR, Toledo JB, Tolnay M, Troncoso JC, Vinters HV, Weis S, Wharton SB, White CL 3rd, Wisniewski T, Woulfe JM, Yamada M, Dickson DW.

Acta Neuropathol. 2016 Jan;131(1):87-102. doi: 10.1007/s00401-015-1509-x. Epub 2015 Dec 10. Review.

19.

The nuclear retention of transcription factor FOXO3a correlates with a DNA damage response and increased glutamine synthetase expression by astrocytes suggesting a neuroprotective role in the ageing brain.

Fluteau A, Ince PG, Minett T, Matthews FE, Brayne C, Garwood CJ, Ratcliffe LE, Morgan S, Heath PR, Shaw PJ, Wharton SB, Simpson JE; MRC Cognitive Function Ageing Neuropathology Study Group.

Neurosci Lett. 2015 Nov 16;609:11-7. doi: 10.1016/j.neulet.2015.10.001. Epub 2015 Oct 8.

20.

Insulin and IGF1 signalling pathways in human astrocytes in vitro and in vivo; characterisation, subcellular localisation and modulation of the receptors.

Garwood CJ, Ratcliffe LE, Morgan SV, Simpson JE, Owens H, Vazquez-Villaseñor I, Heath PR, Romero IA, Ince PG, Wharton SB.

Mol Brain. 2015 Aug 22;8:51. doi: 10.1186/s13041-015-0138-6.

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