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Items: 1 to 20 of 39

1.

Caprazamycins: Biosynthesis and structure activity relationship studies.

Wiker F, Hauck N, Grond S, Gust B.

Int J Med Microbiol. 2019 May 24. pii: S1438-4221(19)30011-6. doi: 10.1016/j.ijmm.2019.05.004. [Epub ahead of print] Review.

PMID:
31138496
2.

Synthetic Lugdunin Analogues Reveal Essential Structural Motifs for Antimicrobial Action and Proton Translocation Capability.

Schilling NA, Berscheid A, Schumacher J, Saur JS, Konnerth MC, Wirtz SN, Beltrán-Beleña JM, Zipperer A, Krismer B, Peschel A, Kalbacher H, Brötz-Oesterhelt H, Steinem C, Grond S.

Angew Chem Int Ed Engl. 2019 May 6. doi: 10.1002/anie.201901589. [Epub ahead of print]

PMID:
31059155
3.

Cyanobacterial antimetabolite 7-deoxy-sedoheptulose blocks the shikimate pathway to inhibit the growth of prototrophic organisms.

Brilisauer K, Rapp J, Rath P, Schöllhorn A, Bleul L, Weiß E, Stahl M, Grond S, Forchhammer K.

Nat Commun. 2019 Feb 1;10(1):545. doi: 10.1038/s41467-019-08476-8.

4.

Lysoquinone-TH1, a New Polyphenolic Tridecaketide Produced by Expressing the Lysolipin Minimal PKS II in Streptomyces albus.

Hofeditz T, Unsin CE, Wiese J, Imhoff JF, Wohlleben W, Grond S, Weber T.

Antibiotics (Basel). 2018 Jun 28;7(3). pii: E53. doi: 10.3390/antibiotics7030053.

5.

Filling the Gaps in the Kirromycin Biosynthesis: Deciphering the Role of Genes Involved in Ethylmalonyl-CoA Supply and Tailoring Reactions.

Robertsen HL, Musiol-Kroll EM, Ding L, Laiple KJ, Hofeditz T, Wohlleben W, Lee SY, Grond S, Weber T.

Sci Rep. 2018 Feb 19;8(1):3230. doi: 10.1038/s41598-018-21507-6.

6.

Production of functionalized oligo-isoprenoids by enzymatic cleavage of rubber.

Röther W, Birke J, Grond S, Beltran JM, Jendrossek D.

Microb Biotechnol. 2017 Nov;10(6):1426-1433. doi: 10.1111/1751-7915.12748. Epub 2017 Jul 11.

7.

Polyketide Bioderivatization Using the Promiscuous Acyltransferase KirCII.

Musiol-Kroll EM, Zubeil F, Schafhauser T, Härtner T, Kulik A, McArthur J, Koryakina I, Wohlleben W, Grond S, Williams GJ, Lee SY, Weber T.

ACS Synth Biol. 2017 Mar 17;6(3):421-427. doi: 10.1021/acssynbio.6b00341. Epub 2017 Feb 22.

8.

Corrigendum: Human commensals producing a novel antibiotic impair pathogen colonization.

Zipperer A, Konnerth MC, Laux C, Berscheid A, Janek D, Weidenmaier C, Burian M, Schilling NA, Slavetinsky C, Marschal M, Willmann M, Kalbacher H, Schittek B, Brötz-Oesterhelt H, Grond S, Peschel A, Krismer B.

Nature. 2016 Nov 10;539(7628):314. doi: 10.1038/nature19781. Epub 2016 Sep 14. No abstract available.

PMID:
27626388
9.

Human commensals producing a novel antibiotic impair pathogen colonization.

Zipperer A, Konnerth MC, Laux C, Berscheid A, Janek D, Weidenmaier C, Burian M, Schilling NA, Slavetinsky C, Marschal M, Willmann M, Kalbacher H, Schittek B, Brötz-Oesterhelt H, Grond S, Peschel A, Krismer B.

Nature. 2016 Jul 28;535(7613):511-6. doi: 10.1038/nature18634. Erratum in: Nature. 2016 Nov 10;539(7628):314.

PMID:
27466123
10.

Rare actinomycetes Nocardia caishijiensis and Pseudonocardia carboxydivorans as endophytes, their bioactivity and metabolites evaluation.

Tanvir R, Sajid I, Hasnain S, Kulik A, Grond S.

Microbiol Res. 2016 Apr;185:22-35. doi: 10.1016/j.micres.2016.01.003. Epub 2016 Jan 23.

11.

Epoxomicin and Eponemycin Biosynthesis Involves gem-Dimethylation and an Acyl-CoA Dehydrogenase-Like Enzyme.

Zettler J, Zubeil F, Kulik A, Grond S, Kaysser L.

Chembiochem. 2016 May 3;17(9):792-8. doi: 10.1002/cbic.201500567. Epub 2016 Feb 25.

PMID:
26789439
12.

A new quinolinone and its natural/artificial derivatives from a shark gill-derived fungus Penicillium polonicum AP2T1.

Zhang Y, Mu J, Essmann F, Feng Y, Kramer M, Bao HY, Grond S.

Nat Prod Res. 2017 May;31(9):985-989. doi: 10.1080/14786419.2015.1045906. Epub 2015 Jul 17. Erratum in: Nat Prod Res. 2017 May;31(9):1106.

PMID:
26186097
13.

New aminocoumarins from the rare actinomycete Catenulispora acidiphila DSM 44928: identification, structure elucidation, and heterologous production.

Zettler J, Xia H, Burkard N, Kulik A, Grond S, Heide L, Apel AK.

Chembiochem. 2014 Mar 3;15(4):612-21. doi: 10.1002/cbic.201300712. Epub 2014 Feb 19.

PMID:
24554531
14.

Unusual N-prenylation in diazepinomicin biosynthesis: the farnesylation of a benzodiazepine substrate is catalyzed by a new member of the ABBA prenyltransferase superfamily.

Bonitz T, Zubeil F, Grond S, Heide L.

PLoS One. 2013 Dec 23;8(12):e85707. doi: 10.1371/journal.pone.0085707. eCollection 2013.

15.

A new class of quorum quenching molecules from Staphylococcus species affects communication and growth of gram-negative bacteria.

Chu YY, Nega M, Wölfle M, Plener L, Grond S, Jung K, Götz F.

PLoS Pathog. 2013;9(9):e1003654. doi: 10.1371/journal.ppat.1003654. Epub 2013 Sep 26.

16.

A two-step sulfation in antibiotic biosynthesis requires a type III polyketide synthase.

Tang X, Eitel K, Kaysser L, Kulik A, Grond S, Gust B.

Nat Chem Biol. 2013 Oct;9(10):610-5. doi: 10.1038/nchembio.1310. Epub 2013 Aug 4.

PMID:
23912167
17.

Antioxidant and anti-protease activities of diazepinomicin from the sponge-associated Micromonospora strain RV115.

Abdelmohsen UR, Szesny M, Othman EM, Schirmeister T, Grond S, Stopper H, Hentschel U.

Mar Drugs. 2012 Oct;10(10):2208-21. doi: 10.3390/md10102208. Epub 2012 Oct 8.

18.

The binding site of the V-ATPase inhibitor apicularen is in the vicinity of those for bafilomycin and archazolid.

Osteresch C, Bender T, Grond S, von Zezschwitz P, Kunze B, Jansen R, Huss M, Wieczorek H.

J Biol Chem. 2012 Sep 14;287(38):31866-76. doi: 10.1074/jbc.M112.372169. Epub 2012 Jul 19.

19.

A novel metagenomic short-chain dehydrogenase/reductase attenuates Pseudomonas aeruginosa biofilm formation and virulence on Caenorhabditis elegans.

Bijtenhoorn P, Mayerhofer H, Müller-Dieckmann J, Utpatel C, Schipper C, Hornung C, Szesny M, Grond S, Thürmer A, Brzuszkiewicz E, Daniel R, Dierking K, Schulenburg H, Streit WR.

PLoS One. 2011;6(10):e26278. doi: 10.1371/journal.pone.0026278. Epub 2011 Oct 26.

20.

Two pathways for pyrrole formation in coumermycin A(1) biosynthesis: the central pyrrole moiety is formed from L-threonine.

Siebenberg S, Burkard N, Knuplesch A, Gust B, Grond S, Heide L.

Chembiochem. 2011 Nov 25;12(17):2677-85. doi: 10.1002/cbic.201100494. Epub 2011 Sep 27.

PMID:
21953874

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