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Items: 1 to 20 of 40

1.

Discovery of Kynurenines Containing Oligopeptides as Potent Opioid Receptor Agonists.

Szűcs E, Stefanucci A, Dimmito MP, Zádor F, Pieretti S, Zengin G, Vécsei L, Benyhe S, Nalli M, Mollica A.

Biomolecules. 2020 Feb 12;10(2). pii: E284. doi: 10.3390/biom10020284.

2.

Potent, Efficacious, and Stable Cyclic Opioid Peptides with Long Lasting Antinociceptive Effect after Peripheral Administration.

Stefanucci A, Dimmito MP, Macedonio G, Ciarlo L, Pieretti S, Novellino E, Lei W, Barlow D, Houseknecht KL, Streicher JM, Mollica A.

J Med Chem. 2020 Mar 12;63(5):2673-2687. doi: 10.1021/acs.jmedchem.9b01963. Epub 2019 Dec 27.

PMID:
31834798
3.

Discovery of Orexant and Anorexant Agents with Indazole Scaffold Endowed with Peripheral Antiedema Activity.

Dimmito MP, Stefanucci A, Pieretti S, Minosi P, Dvorácskó S, Tömböly C, Zengin G, Mollica A.

Biomolecules. 2019 Sep 16;9(9). pii: E492. doi: 10.3390/biom9090492.

4.

IL-17A neutralizing antibody regulates monosodium urate crystal-induced gouty inflammation.

Raucci F, Iqbal AJ, Saviano A, Minosi P, Piccolo M, Irace C, Caso F, Scarpa R, Pieretti S, Mascolo N, Maione F.

Pharmacol Res. 2019 Sep;147:104351. doi: 10.1016/j.phrs.2019.104351. Epub 2019 Jul 14.

PMID:
31315067
5.

Long-Lasting Anti-Inflammatory and Antinociceptive Effects of Acute Ammonium Glycyrrhizinate Administration: Pharmacological, Biochemical, and Docking Studies.

Maione F, Minosi P, Di Giannuario A, Raucci F, Chini MG, De Vita S, Bifulco G, Mascolo N, Pieretti S.

Molecules. 2019 Jul 4;24(13). pii: E2453. doi: 10.3390/molecules24132453.

6.

Preparation of bivalent agonists for targeting the mu opioid and cannabinoid receptors.

Dvorácskó S, Keresztes A, Mollica A, Stefanucci A, Macedonio G, Pieretti S, Zádor F, Walter FR, Deli MA, Kékesi G, Bánki L, Tuboly G, Horváth G, Tömböly C.

Eur J Med Chem. 2019 Sep 15;178:571-588. doi: 10.1016/j.ejmech.2019.05.037. Epub 2019 May 21.

PMID:
31220675
7.

Beneficial Role of Phytochemicals on Oxidative Stress and Age-Related Diseases.

Forni C, Facchiano F, Bartoli M, Pieretti S, Facchiano A, D'Arcangelo D, Norelli S, Valle G, Nisini R, Beninati S, Tabolacci C, Jadeja RN.

Biomed Res Int. 2019 Apr 7;2019:8748253. doi: 10.1155/2019/8748253. eCollection 2019. Review.

8.

Novel Cyclic Biphalin Analogues by Ruthenium-Catalyzed Ring Closing Metathesis: in Vivo and in Vitro Biological Profile.

Stefanucci A, Lei W, Pieretti S, Dimmito MP, Luisi G, Novellino E, Nowakowski M, Koźmiński W, Mirzaie S, Zengin G, Streicher JM, Mollica A.

ACS Med Chem Lett. 2019 Mar 8;10(4):450-456. doi: 10.1021/acsmedchemlett.8b00495. eCollection 2019 Apr 11.

PMID:
30996778
9.

On resin click-chemistry-mediated synthesis of novel enkephalin analogues with potent anti-nociceptive activity.

Stefanucci A, Lei W, Pieretti S, Novellino E, Dimmito MP, Marzoli F, Streicher JM, Mollica A.

Sci Rep. 2019 Apr 8;9(1):5771. doi: 10.1038/s41598-019-42289-5.

10.

Long-Lasting, Antinociceptive Effects of pH-Sensitive Niosomes Loaded with Ibuprofen in Acute and Chronic Models of Pain.

Marzoli F, Marianecci C, Rinaldi F, Passeri D, Rossi M, Minosi P, Carafa M, Pieretti S.

Pharmaceutics. 2019 Feb 1;11(2). pii: E62. doi: 10.3390/pharmaceutics11020062.

11.

Antinociceptive potency of a fluorinated cyclopeptide Dmt-c[D-Lys-Phe-p-CF3-Phe-Asp]NH2.

Piekielna-Ciesielska J, Mollica A, Pieretti S, Fichna J, Szymaszkiewicz A, Zielińska M, Kordek R, Janecka A.

J Enzyme Inhib Med Chem. 2018 Dec;33(1):560-566. doi: 10.1080/14756366.2018.1441839.

12.

Nociceptin /Orphanin FQ Peptide (NOP) Receptor Modulators: An Update in Structure-Activity Relationships.

Mustazza C, Pieretti S, Marzoli F.

Curr Med Chem. 2018;25(20):2353-2384. doi: 10.2174/0929867325666180111095458. Review.

PMID:
29332567
13.

Cyclic Biphalin Analogues Incorporating a Xylene Bridge: Synthesis, Characterization, and Biological Profile.

Stefanucci A, Carotenuto A, Macedonio G, Novellino E, Pieretti S, Marzoli F, Szűcs E, Erdei AI, Zádor F, Benyhe S, Mollica A.

ACS Med Chem Lett. 2017 Jul 12;8(8):858-863. doi: 10.1021/acsmedchemlett.7b00210. eCollection 2017 Aug 10.

14.

"Curcumin-loaded Poly (d, l-lactide-co-glycolide) nanovesicles induce antinociceptive effects and reduce pronociceptive cytokine and BDNF release in spinal cord after acute administration in mice".

Pieretti S, Ranjan AP, Di Giannuario A, Mukerjee A, Marzoli F, Di Giovannandrea R, Vishwanatha JK.

Colloids Surf B Biointerfaces. 2017 Oct 1;158:379-386. doi: 10.1016/j.colsurfb.2017.07.027. Epub 2017 Jul 10.

PMID:
28719859
15.

Opioid Receptor Activity and Analgesic Potency of DPDPE Peptide Analogues Containing a Xylene Bridge.

Stefanucci A, Novellino E, Mirzaie S, Macedonio G, Pieretti S, Minosi P, Szűcs E, Erdei AI, Zádor F, Benyhe S, Mollica A.

ACS Med Chem Lett. 2017 Mar 14;8(4):449-454. doi: 10.1021/acsmedchemlett.7b00044. eCollection 2017 Apr 13.

16.

pH-sensitive niosomes: Effects on cytotoxicity and on inflammation and pain in murine models.

Rinaldi F, Del Favero E, Rondelli V, Pieretti S, Bogni A, Ponti J, Rossi F, Di Marzio L, Paolino D, Marianecci C, Carafa M.

J Enzyme Inhib Med Chem. 2017 Dec;32(1):538-546. doi: 10.1080/14756366.2016.1268607.

17.

Exploring the first Rimonabant analog-opioid peptide hybrid compound, as bivalent ligand for CB1 and opioid receptors.

Mollica A, Pelliccia S, Famiglini V, Stefanucci A, Macedonio G, Chiavaroli A, Orlando G, Brunetti L, Ferrante C, Pieretti S, Novellino E, Benyhe S, Zador F, Erdei A, Szucs E, Samavati R, Dvrorasko S, Tomboly C, Ragno R, Patsilinakos A, Silvestri R.

J Enzyme Inhib Med Chem. 2017 Dec;32(1):444-451. doi: 10.1080/14756366.2016.1260565.

18.

Anti-inflammatory and analgesic activity of carnosol and carnosic acid in vivo and in vitro and in silico analysis of their target interactions.

Maione F, Cantone V, Pace S, Chini MG, Bisio A, Romussi G, Pieretti S, Werz O, Koeberle A, Mascolo N, Bifulco G.

Br J Pharmacol. 2017 Jun;174(11):1497-1508. doi: 10.1111/bph.13545. Epub 2016 Aug 8.

19.

Gender differences in pain and its relief.

Pieretti S, Di Giannuario A, Di Giovannandrea R, Marzoli F, Piccaro G, Minosi P, Aloisi AM.

Ann Ist Super Sanita. 2016 Apr-Jun;52(2):184-9. doi: 10.4415/ANN_16_02_09. Review.

20.

Evaluation of the analgesic effect of 4-anilidopiperidine scaffold containing ureas and carbamates.

Monti L, Stefanucci A, Pieretti S, Marzoli F, Fidanza L, Mollica A, Mirzaie S, Carradori S, De Petrocellis L, Schiano Moriello A, Benyhe S, Zádor F, Szűcs E, Ötvös F, Erdei AI, Samavati R, Dvorácskó S, Tömböly C, Novellino E.

J Enzyme Inhib Med Chem. 2016 Dec;31(6):1638-47. doi: 10.3109/14756366.2016.1160902. Epub 2016 Apr 11.

PMID:
27063555

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