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Items: 1 to 20 of 54

1.

Cannabinoid Receptor 2 Modulates Maturation of Dendritic Cells and Their Capacity to Induce Hapten-Induced Contact Hypersensitivity.

Gaffal E, Kemter AM, Scheu S, Leite Dantas R, Vogt J, Baune B, Tüting T, Zimmer A, Alferink J.

Int J Mol Sci. 2020 Jan 11;21(2). pii: E475. doi: 10.3390/ijms21020475.

2.

A mouse model-based screening platform for the identification of immune activating compounds such as natural products for novel cancer immunotherapies.

Richter L, Kropp S, Proksch P, Scheu S.

Bioorg Med Chem. 2019 Dec 1;27(23):115145. doi: 10.1016/j.bmc.2019.115145. Epub 2019 Oct 9.

3.

Production of IFNβ by Conventional Dendritic Cells after Stimulation with Viral Compounds and IFNβ-Independent IFNAR1-Signaling Pathways are Associated with Aggravation of Polymicrobial Sepsis.

Howe M, Bauer J, Schulze A, Kropp S, Locksley RM, Alferink J, Weighardt H, Scheu S.

Int J Mol Sci. 2019 Sep 7;20(18). pii: E4410. doi: 10.3390/ijms20184410.

4.

Social Defeat Modulates T Helper Cell Percentages in Stress Susceptible and Resilient Mice.

Ambrée O, Ruland C, Zwanzger P, Klotz L, Baune BT, Arolt V, Scheu S, Alferink J.

Int J Mol Sci. 2019 Jul 17;20(14). pii: E3512. doi: 10.3390/ijms20143512.

5.

Sources of Type I Interferons in Infectious Immunity: Plasmacytoid Dendritic Cells Not Always in the Driver's Seat.

Ali S, Mann-Nüttel R, Schulze A, Richter L, Alferink J, Scheu S.

Front Immunol. 2019 Apr 12;10:778. doi: 10.3389/fimmu.2019.00778. eCollection 2019. Review.

6.

Mitochondria, Microglia, and the Immune System-How Are They Linked in Affective Disorders?

Culmsee C, Michels S, Scheu S, Arolt V, Dannlowski U, Alferink J.

Front Psychiatry. 2019 Jan 9;9:739. doi: 10.3389/fpsyt.2018.00739. eCollection 2018. Review.

7.

Interferon β-Mediated Protective Functions of Microglia in Central Nervous System Autoimmunity.

Scheu S, Ali S, Mann-Nüttel R, Richter L, Arolt V, Dannlowski U, Kuhlmann T, Klotz L, Alferink J.

Int J Mol Sci. 2019 Jan 7;20(1). pii: E190. doi: 10.3390/ijms20010190. Review.

8.

Alterations of the Innate Immune System in Susceptibility and Resilience After Social Defeat Stress.

Ambrée O, Ruland C, Scheu S, Arolt V, Alferink J.

Front Behav Neurosci. 2018 Jul 13;12:141. doi: 10.3389/fnbeh.2018.00141. eCollection 2018.

9.

Hepatic Rac1 GTPase contributes to liver-mediated basal immune homeostasis and LPS-induced endotoxemia.

Pohlmann S, Scheu S, Ziegler V, Schupp N, Henninger C, Fritz G.

Biochim Biophys Acta Mol Cell Res. 2018 Sep;1865(9):1277-1292. doi: 10.1016/j.bbamcr.2018.06.007. Epub 2018 Jun 20.

10.

Identification of a novel Dlg2 isoform differentially expressed in IFNβ-producing plasmacytoid dendritic cells.

Ali S, Hoven A, Dress RJ, Schaal H, Alferink J, Scheu S.

BMC Genomics. 2018 Mar 12;19(1):194. doi: 10.1186/s12864-018-4573-5.

11.

Sphingosine 1-Phosphate- and C-C Chemokine Receptor 2-Dependent Activation of CD4+ Plasmacytoid Dendritic Cells in the Bone Marrow Contributes to Signs of Sepsis-Induced Immunosuppression.

Smirnov A, Pohlmann S, Nehring M, Ali S, Mann-Nüttel R, Scheu S, Antoni AC, Hansen W, Büettner M, Gardiasch MJ, Westendorf AM, Wirsdörfer F, Pastille E, Dudda M, Flohé SB.

Front Immunol. 2017 Nov 23;8:1622. doi: 10.3389/fimmu.2017.01622. eCollection 2017.

12.

Tumor Necrosis Factor-Mediated Survival of CD169+ Cells Promotes Immune Activation during Vesicular Stomatitis Virus Infection.

Shinde PV, Xu HC, Maney SK, Kloetgen A, Namineni S, Zhuang Y, Honke N, Shaabani N, Bellora N, Doerrenberg M, Trilling M, Pozdeev VI, van Rooijen N, Scheu S, Pfeffer K, Crocker PR, Tanaka M, Duggimpudi S, Knolle P, Heikenwalder M, Ruland J, Mak TW, Brenner D, Pandyra AA, Hoell JI, Borkhardt A, Häussinger D, Lang KS, Lang PA.

J Virol. 2018 Jan 17;92(3). pii: e01637-17. doi: 10.1128/JVI.01637-17. Print 2018 Feb 1.

13.

The C-C Chemokines CCL17 and CCL22 and Their Receptor CCR4 in CNS Autoimmunity.

Scheu S, Ali S, Ruland C, Arolt V, Alferink J.

Int J Mol Sci. 2017 Nov 2;18(11). pii: E2306. doi: 10.3390/ijms18112306. Review.

14.

Altered B Cell Homeostasis in Patients with Major Depressive Disorder and Normalization of CD5 Surface Expression on Regulatory B Cells in Treatment Responders.

Ahmetspahic D, Schwarte K, Ambrée O, Bürger C, Falcone V, Seiler K, Kooybaran MR, Grosse L, Roos F, Scheffer J, Jörgens S, Koelkebeck K, Dannlowski U, Arolt V, Scheu S, Alferink J.

J Neuroimmune Pharmacol. 2018 Mar;13(1):90-99. doi: 10.1007/s11481-017-9763-4. Epub 2017 Sep 13.

PMID:
28905187
15.

Chemokine CCL17 is expressed by dendritic cells in the CNS during experimental autoimmune encephalomyelitis and promotes pathogenesis of disease.

Ruland C, Renken H, Kuzmanov I, Fattahi Mehr A, Schwarte K, Cerina M, Herrmann A, Otte DM, Zimmer A, Schwab N, Meuth SG, Arolt V, Klotz L, Förster I, Scheu S, Alferink J.

Brain Behav Immun. 2017 Nov;66:382-393. doi: 10.1016/j.bbi.2017.06.010. Epub 2017 Jun 19.

PMID:
28642092
16.

Spatiotemporally restricted arenavirus replication induces immune surveillance and type I interferon-dependent tumour regression.

Kalkavan H, Sharma P, Kasper S, Helfrich I, Pandyra AA, Gassa A, Virchow I, Flatz L, Brandenburg T, Namineni S, Heikenwalder M, Höchst B, Knolle PA, Wollmann G, von Laer D, Drexler I, Rathbun J, Cannon PM, Scheu S, Bauer J, Chauhan J, Häussinger D, Willimsky G, Löhning M, Schadendorf D, Brandau S, Schuler M, Lang PA, Lang KS.

Nat Commun. 2017 Mar 1;8:14447. doi: 10.1038/ncomms14447.

17.

CD169+ macrophages regulate PD-L1 expression via type I interferon and thereby prevent severe immunopathology after LCMV infection.

Shaabani N, Duhan V, Khairnar V, Gassa A, Ferrer-Tur R, Häussinger D, Recher M, Zelinskyy G, Liu J, Dittmer U, Trilling M, Scheu S, Hardt C, Lang PA, Honke N, Lang KS.

Cell Death Dis. 2016 Nov 3;7(11):e2446. doi: 10.1038/cddis.2016.350.

18.

Alemtuzumab treatment alters circulating innate immune cells in multiple sclerosis.

Gross CC, Ahmetspahic D, Ruck T, Schulte-Mecklenbeck A, Schwarte K, Jörgens S, Scheu S, Windhagen S, Graefe B, Melzer N, Klotz L, Arolt V, Wiendl H, Meuth SG, Alferink J.

Neurol Neuroimmunol Neuroinflamm. 2016 Oct 12;3(6):e289. eCollection 2016 Dec.

19.

In Vivo Conditions Enable IFNAR-Independent Type I Interferon Production by Peritoneal CD11b+ Cells upon Thogoto Virus Infection.

Kochs G, Anzaghe M, Kronhart S, Wagner V, Gogesch P, Scheu S, Lienenklaus S, Waibler Z.

J Virol. 2016 Sep 29;90(20):9330-7. doi: 10.1128/JVI.00744-16. Print 2016 Oct 15.

20.

Cannabinoid Receptor 2 Modulates Susceptibility to Experimental Cerebral Malaria through a CCL17-dependent Mechanism.

Alferink J, Specht S, Arends H, Schumak B, Schmidt K, Ruland C, Lundt R, Kemter A, Dlugos A, Kuepper JM, Poppensieker K, Findeiss M, Albayram Ö, Otte DM, Marazzi J, Gertsch J, Förster I, Maier W, Scheu S, Hoerauf A, Zimmer A.

J Biol Chem. 2016 Sep 9;291(37):19517-31. doi: 10.1074/jbc.M116.746594. Epub 2016 Jul 29.

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