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Items: 10

1.

Senescence Phenomena and Metabolic Alteration in Mesenchymal Stromal Cells from a Mouse Model of Rett Syndrome.

Squillaro T, Alessio N, Capasso S, Di Bernardo G, Melone MAB, Peluso G, Galderisi U.

Int J Mol Sci. 2019 May 21;20(10). pii: E2508. doi: 10.3390/ijms20102508.

2.

Neural stem cells from a mouse model of Rett syndrome are prone to senescence, show reduced capacity to cope with genotoxic stress, and are impaired in the differentiation process.

Alessio N, Riccitiello F, Squillaro T, Capasso S, Del Gaudio S, Di Bernardo G, Cipollaro M, Melone MAB, Peluso G, Galderisi U.

Exp Mol Med. 2018 Mar 22;50(3):1. doi: 10.1038/s12276-017-0005-x.

3.

Misidentified Human Gene Functions with Mouse Models: The Case of the Retinoblastoma Gene Family in Senescence.

Alessio N, Capasso S, Ferone A, Di Bernardo G, Cipollaro M, Casale F, Peluso G, Giordano A, Galderisi U.

Neoplasia. 2017 Oct;19(10):781-790. doi: 10.1016/j.neo.2017.06.005. Epub 2017 Aug 30.

4.

Mesenchymal stromal cells having inactivated RB1 survive following low irradiation and accumulate damaged DNA: Hints for side effects following radiotherapy.

Alessio N, Capasso S, Di Bernardo G, Cappabianca S, Casale F, Calarco A, Cipollaro M, Peluso G, Galderisi U.

Cell Cycle. 2017 Feb;16(3):251-258. doi: 10.1080/15384101.2016.1175798. Epub 2016 Apr 28.

5.

Changes in autophagy, proteasome activity and metabolism to determine a specific signature for acute and chronic senescent mesenchymal stromal cells.

Capasso S, Alessio N, Squillaro T, Di Bernardo G, Melone MA, Cipollaro M, Peluso G, Galderisi U.

Oncotarget. 2015 Nov 24;6(37):39457-68. doi: 10.18632/oncotarget.6277.

6.

Low dose radiation induced senescence of human mesenchymal stromal cells and impaired the autophagy process.

Alessio N, Del Gaudio S, Capasso S, Di Bernardo G, Cappabianca S, Cipollaro M, Peluso G, Galderisi U.

Oncotarget. 2015 Apr 10;6(10):8155-66.

7.

Sera of overweight people promote in vitro adipocyte differentiation of bone marrow stromal cells.

Di Bernardo G, Messina G, Capasso S, Del Gaudio S, Cipollaro M, Peluso G, Casale F, Monda M, Galderisi U.

Stem Cell Res Ther. 2014 Jan 9;5(1):4. doi: 10.1186/scrt393.

8.

Silencing of RB1 and RB2/P130 during adipogenesis of bone marrow stromal cells results in dysregulated differentiation.

Capasso S, Alessio N, Di Bernardo G, Cipollaro M, Melone MA, Peluso G, Giordano A, Galderisi U.

Cell Cycle. 2014;13(3):482-90. doi: 10.4161/cc.27275. Epub 2013 Nov 26.

9.

Low concentrations of isothiocyanates protect mesenchymal stem cells from oxidative injuries, while high concentrations exacerbate DNA damage.

Zanichelli F, Capasso S, Di Bernardo G, Cipollaro M, Pagnotta E, Cartenì M, Casale F, Iori R, Giordano A, Galderisi U.

Apoptosis. 2012 Sep;17(9):964-74. doi: 10.1007/s10495-012-0740-3.

PMID:
22684843
10.

Dose-dependent effects of R-sulforaphane isothiocyanate on the biology of human mesenchymal stem cells, at dietary amounts, it promotes cell proliferation and reduces senescence and apoptosis, while at anti-cancer drug doses, it has a cytotoxic effect.

Zanichelli F, Capasso S, Cipollaro M, Pagnotta E, Cartenì M, Casale F, Iori R, Galderisi U.

Age (Dordr). 2012 Apr;34(2):281-93. doi: 10.1007/s11357-011-9231-7. Epub 2011 Apr 6.

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