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Items: 18

1.

Potent and Broad but not Unselective Cleavage of Cytokines and Chemokines by Human Neutrophil Elastase and Proteinase 3.

Fu Z, Akula S, Thorpe M, Hellman L.

Int J Mol Sci. 2020 Jan 19;21(2). pii: E651. doi: 10.3390/ijms21020651.

2.

Quantitative In-Depth Analysis of the Mouse Mast Cell Transcriptome Reveals Organ-Specific Mast Cell Heterogeneity.

Akula S, Paivandy A, Fu Z, Thorpe M, Pejler G, Hellman L.

Cells. 2020 Jan 14;9(1). pii: E211. doi: 10.3390/cells9010211.

3.

Extended cleavage specificities of two mast cell chymase-related proteases and one granzyme B-like protease from the platypus, a monotreme.

Fu Z, Akula S, Thorpe M, Hellman L.

Int J Mol Sci. 2020 Jan 2;21(1). pii: E319. doi: 10.3390/ijms21010319.

4.

Protective role of mouse mast cell tryptase Mcpt6 in melanoma.

Grujic M, Hellman L, Gustafson AM, Akula S, Melo FR, Pejler G.

Pigment Cell Melanoma Res. 2020 Jan 1. doi: 10.1111/pcmr.12859. [Epub ahead of print]

PMID:
31894627
5.

Extended Cleavage Specificities of Rabbit and Guinea Pig Mast Cell Chymases: Two Highly Specific Leu-Ases.

Zhongwei Y, Akula S, Fu Z, de Garavilla L, Kervinen J, Thorpe M, Hellman L.

Int J Mol Sci. 2019 Dec 16;20(24). pii: E6340. doi: 10.3390/ijms20246340.

6.
7.

Extended cleavage specificities of mast cell proteases 1 and 2 from golden hamster: Classical chymase and an elastolytic protease comparable to rat and mouse MCP-5.

Thorpe M, Fu Z, Albat E, Akula S, de Garavilla L, Kervinen J, Hellman L.

PLoS One. 2018 Dec 6;13(12):e0207826. doi: 10.1371/journal.pone.0207826. eCollection 2018.

8.

Extended cleavage specificity of sheep mast cell protease-2: A classical chymase with preference to aromatic P1 substrate residues.

Fu Z, Akula S, Thorpe M, Chahal G, de Garavilla L, Kervinen J, Hellman L.

Dev Comp Immunol. 2019 Mar;92:160-169. doi: 10.1016/j.dci.2018.11.019. Epub 2018 Nov 24.

PMID:
30481523
9.
10.

Extended cleavage specificity of human neutrophil cathepsin G: A low activity protease with dual chymase and tryptase-type specificities.

Thorpe M, Fu Z, Chahal G, Akula S, Kervinen J, de Garavilla L, Hellman L.

PLoS One. 2018 Apr 13;13(4):e0195077. doi: 10.1371/journal.pone.0195077. eCollection 2018.

11.

Tracing the Origins of IgE, Mast Cells, and Allergies by Studies of Wild Animals.

Hellman LT, Akula S, Thorpe M, Fu Z.

Front Immunol. 2017 Dec 19;8:1749. doi: 10.3389/fimmu.2017.01749. eCollection 2017. Review.

12.

The Appearance and Diversification of Receptors for IgM During Vertebrate Evolution.

Akula S, Hellman L.

Curr Top Microbiol Immunol. 2017;408:1-23. doi: 10.1007/82_2017_22. Review.

PMID:
28884191
13.

Channel catfish granzyme-like I is a highly specific serine protease with metase activity that is expressed by fish NK-like cells.

Thorpe M, Akula S, Hellman L.

Dev Comp Immunol. 2016 Oct;63:84-95. doi: 10.1016/j.dci.2016.05.013. Epub 2016 May 20.

PMID:
27216028
14.

Asp-ase Activity of the Opossum Granzyme B Supports the Role of Granzyme B as Part of Anti-Viral Immunity Already during Early Mammalian Evolution.

Fu Z, Thorpe M, Akula S, Hellman L.

PLoS One. 2016 May 6;11(5):e0154886. doi: 10.1371/journal.pone.0154886. eCollection 2016.

15.

Correction: Granule Associated Serine Proteases of Hematopoietic Cells - An Analysis of Their Appearance and Diversification during Vertebrate Evolution.

Akula S, Thorpe M, Boinapally V, Hellman L.

PLoS One. 2015 Dec 22;10(12):e0145592. doi: 10.1371/journal.pone.0145592. eCollection 2015. No abstract available.

16.

Granule Associated Serine Proteases of Hematopoietic Cells - An Analysis of Their Appearance and Diversification during Vertebrate Evolution.

Akula S, Thorpe M, Boinapally V, Hellman L.

PLoS One. 2015 Nov 16;10(11):e0143091. doi: 10.1371/journal.pone.0143091. eCollection 2015. Erratum in: PLoS One. 2015;10(12):e0145592.

17.

Identification of potential drug targets in Helicobacter pylori strain HPAG1 by in silico genome analysis.

Neelapu NR, Mutha NV, Akula S.

Infect Disord Drug Targets. 2015;15(2):106-17.

PMID:
26205802
18.

Fc receptors for immunoglobulins and their appearance during vertebrate evolution.

Akula S, Mohammadamin S, Hellman L.

PLoS One. 2014 May 9;9(5):e96903. doi: 10.1371/journal.pone.0096903. eCollection 2014. Erratum in: PLoS One. 2015;10(4):e0124530.

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