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SIRT1 Attenuates Kidney Disorders in Male Offspring Due to Maternal High-Fat Diet.

Nguyen LT, Mak CH, Chen H, Zaky AA, Wong MG, Pollock CA, Saad S.

Nutrients. 2019 Jan 11;11(1). pii: E146. doi: 10.3390/nu11010146.


SIRT1 overexpression attenuates offspring metabolic and liver disorders as a result of maternal high-fat feeding.

Nguyen LT, Chen H, Zaky A, Pollock C, Saad S.

J Physiol. 2019 Jan;597(2):467-480. doi: 10.1113/JP276957. Epub 2018 Oct 31.


Maternal L-carnitine supplementation ameliorates renal underdevelopment and epigenetic changes in male mice offspring due to maternal smoking.

Stangenberg S, Nguyen LT, Chan YL, Zaky A, Pollock CA, Chen H, Saad S.

Clin Exp Pharmacol Physiol. 2019 Feb;46(2):183-193. doi: 10.1111/1440-1681.13038. Epub 2018 Nov 22.


Heat or Burn? Impacts of Intrauterine Tobacco Smoke and E-Cigarette Vapor Exposure on the Offspring's Health Outcome.

Li G, Saad S, Oliver BG, Chen H.

Toxics. 2018 Aug 1;6(3). pii: E43. doi: 10.3390/toxics6030043. Review.


L-Carnitine and extendin-4 improve outcomes following moderate brain contusion injury.

Chen H, Chan YL, Linnane C, Mao Y, Anwer AG, Sapkota A, Annissa TF, Herok G, Vissel B, Oliver BG, Saad S, Gorrie CA.

Sci Rep. 2018 Jul 25;8(1):11201. doi: 10.1038/s41598-018-29430-6.


Modulation of neural regulators of energy homeostasis, and of inflammation, in the pups of mice exposed to e-cigarettes.

Chen H, Li G, Chan YL, Nguyen T, van Reyk D, Saad S, Oliver BG.

Neurosci Lett. 2018 Sep 25;684:61-66. doi: 10.1016/j.neulet.2018.07.001. Epub 2018 Jul 4.


Lysyl oxidase-like 2 inhibition ameliorates glomerulosclerosis and albuminuria in diabetic nephropathy.

Stangenberg S, Saad S, Schilter HC, Zaky A, Gill A, Pollock CA, Wong MG.

Sci Rep. 2018 Jun 21;8(1):9423. doi: 10.1038/s41598-018-27462-6.


MitoQ supplementation prevent long-term impact of maternal smoking on renal development, oxidative stress and mitochondrial density in male mice offspring.

Sukjamnong S, Chan YL, Zakarya R, Nguyen LT, Anwer AG, Zaky AA, Santiyanont R, Oliver BG, Goldys E, Pollock CA, Chen H, Saad S.

Sci Rep. 2018 Apr 26;8(1):6631. doi: 10.1038/s41598-018-24949-0.


DNA methylation and the potential role of demethylating agents in prevention of progressive chronic kidney disease.

Larkin BP, Glastras SJ, Chen H, Pollock CA, Saad S.

FASEB J. 2018 Oct;32(10):5215-5226. doi: 10.1096/fj.201800205R. Epub 2018 Apr 24.


SRT1720 attenuates obesity and insulin resistance but not liver damage in the offspring due to maternal and postnatal high-fat diet consumption.

Nguyen LT, Chen H, Mak C, Zaky A, Pollock C, Saad S.

Am J Physiol Endocrinol Metab. 2018 Aug 1;315(2):E196-E203. doi: 10.1152/ajpendo.00472.2017. Epub 2018 Mar 13.


Maternal obesity increases the risk of metabolic disease and impacts renal health in offspring.

Glastras SJ, Chen H, Pollock CA, Saad S.

Biosci Rep. 2018 Mar 29;38(2). pii: BSR20180050. doi: 10.1042/BSR20180050. Print 2018 Apr 27. Review.


Maternal Cigarette Smoke Exposure Worsens Neurological Outcomes in Adolescent Offspring with Hypoxic-Ischemic Injury.

Chan YL, Saad S, Machaalani R, Oliver BG, Vissel B, Pollock C, Jones NM, Chen H.

Front Mol Neurosci. 2017 Sep 26;10:306. doi: 10.3389/fnmol.2017.00306. eCollection 2017. Erratum in: Front Mol Neurosci. 2018 Mar 12;11:84.


Effect of long-term maternal smoking on the offspring's lung health.

Sukjamnong S, Chan YL, Zakarya R, Saad S, Sharma P, Santiyanont R, Chen H, Oliver BG.

Am J Physiol Lung Cell Mol Physiol. 2017 Aug 1;313(2):L416-L423. doi: 10.1152/ajplung.00134.2017. Epub 2017 May 18.


Maternal high-fat diet induces metabolic stress response disorders in offspring hypothalamus.

Nguyen LT, Saad S, Tan Y, Pollock C, Chen H.

J Mol Endocrinol. 2017 Jul;59(1):81-92. doi: 10.1530/JME-17-0056. Epub 2017 May 12.


Maternal L-Carnitine Supplementation Improves Brain Health in Offspring from Cigarette Smoke Exposed Mothers.

Chan YL, Saad S, Al-Odat I, Oliver BG, Pollock C, Jones NM, Chen H.

Front Mol Neurosci. 2017 Feb 13;10:33. doi: 10.3389/fnmol.2017.00033. eCollection 2017.


The renal consequences of maternal obesity in offspring are overwhelmed by postnatal high fat diet.

Glastras SJ, Chen H, Tsang M, Teh R, McGrath RT, Zaky A, Chen J, Wong MG, Pollock CA, Saad S.

PLoS One. 2017 Feb 22;12(2):e0172644. doi: 10.1371/journal.pone.0172644. eCollection 2017.


Moderate traumatic brain injury is linked to acute behaviour deficits and long term mitochondrial alterations.

Chen H, Chan YL, Nguyen LT, Mao Y, de Rosa A, Beh IT, Chee C, Oliver B, Herok G, Saad S, Gorrie C.

Clin Exp Pharmacol Physiol. 2016 Nov;43(11):1107-1114. doi: 10.1111/1440-1681.12650.


Mouse Models of Diabetes, Obesity and Related Kidney Disease.

Glastras SJ, Chen H, Teh R, McGrath RT, Chen J, Pollock CA, Wong MG, Saad S.

PLoS One. 2016 Aug 31;11(8):e0162131. doi: 10.1371/journal.pone.0162131. eCollection 2016.


Impact of maternal cigarette smoke exposure on brain and kidney health outcomes in female offspring.

Chan YL, Saad S, Al-Odat I, Zaky AA, Oliver B, Pollock C, Li W, Jones NM, Chen H.

Clin Exp Pharmacol Physiol. 2016 Dec;43(12):1168-1176. doi: 10.1111/1440-1681.12659.


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