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Items: 1 to 20 of 36


Monocytes as Endothelial Progenitor Cells (EPCs), Another Brick in the Wall to Disentangle Tumor Angiogenesis.

Lopes-Coelho F, Silva F, Gouveia-Fernandes S, Martins C, Lopes N, Domingues G, Brito C, Almeida AM, Pereira SA, Serpa J.

Cells. 2020 Jan 1;9(1). pii: E107. doi: 10.3390/cells9010107.


Targeting Glutathione and Cystathionine β-Synthase in Ovarian Cancer Treatment by Selenium-Chrysin Polyurea Dendrimer Nanoformulation.

Santos I, Ramos C, Mendes C, Sequeira CO, Tomé CS, Fernandes DGH, Mota P, Pires RF, Urso D, Hipólito A, Antunes AMM, Vicente JB, Pereira SA, Bonifácio VDB, Nunes SC, Serpa J.

Nutrients. 2019 Oct 19;11(10). pii: E2523. doi: 10.3390/nu11102523.


Special Issue "Adductomics: Elucidating the Environmental Causes of Disease".

Pereira SA, Antunes AMM.

High Throughput. 2019 Jul 31;8(3). pii: E17. doi: 10.3390/ht8030017.


The mercapturomic profile of health and non-communicable diseases.

Gonçalves-Dias C, Morello J, Semedo V, Correia MJ, Coelho NR, Monteiro EC, Antunes AMM, Pereira SA.

High Throughput. 2019 Apr 23;8(2). pii: E10. doi: 10.3390/ht8020010. Review.


Mass Spectrometry-Based Methodologies for Targeted and Untargeted Identification of Protein Covalent Adducts (Adductomics): Current Status and Challenges.

Nunes J, Charneira C, Morello J, Rodrigues J, Pereira SA, Antunes AMM.

High Throughput. 2019 Apr 23;8(2). pii: E9. doi: 10.3390/ht8020009. Review.


Anti-tumorigenic and Platinum-Sensitizing Effects of Apolipoprotein A1 and Apolipoprotein A1 Mimetic Peptides in Ovarian Cancer.

Marinho AT, Lu H, Pereira SA, Monteiro E, Gabra H, Recchi C.

Front Pharmacol. 2019 Jan 28;9:1524. doi: 10.3389/fphar.2018.01524. eCollection 2018.


Singularities of nevirapine metabolism: from sex-dependent differences to idiosyncratic toxicity.

Marinho AT, Miranda JP, Caixas U, Charneira C, Gonçalves-Dias C, Marques MM, Monteiro EC, Antunes AMM, Pereira SA.

Drug Metab Rev. 2019 Feb;51(1):76-90. doi: 10.1080/03602532.2019.1577891. Epub 2019 Mar 29. Review.


Mercapturate Pathway in the Tubulocentric Perspective of Diabetic Kidney Disease.

Gonçalves-Dias C, Morello J, Correia MJ, Coelho NR, Antunes AMM, Macedo MP, Monteiro EC, Soto K, Pereira SA.

Nephron. 2019;143(1):17-23. doi: 10.1159/000494390. Epub 2019 Jan 9. Review.


Zebrafish Larvae Are a Suitable Model to Investigate the Metabolic Phenotype of Drug-Induced Renal Tubular Injury.

Morello J, Derks RJE, Lopes SS, Steenvoorden E, Monteiro EC, Mayboroda OA, Pereira SA.

Front Pharmacol. 2018 Oct 16;9:1193. doi: 10.3389/fphar.2018.01193. eCollection 2018.


Cysteine Oxidative Dynamics Underlies Hypertension and Kidney Dysfunction Induced by Chronic Intermittent Hypoxia.

Coelho NR, Dias CG, João Correia M, Grácio P, Serpa J, Monteiro EC, Diogo LN, Pereira SA.

Adv Exp Med Biol. 2018;1071:83-88. doi: 10.1007/978-3-319-91137-3_10.


The first-line antiepileptic drug carbamazepine: Reaction with biologically relevant free radicals.

Martins IL, Nunes J, Charneira C, Morello J, Pereira SA, Telo JP, Marques MM, Antunes AMM.

Free Radic Biol Med. 2018 Dec;129:559-568. doi: 10.1016/j.freeradbiomed.2018.10.408. Epub 2018 Oct 17.


Cysteine allows ovarian cancer cells to adapt to hypoxia and to escape from carboplatin cytotoxicity.

Nunes SC, Ramos C, Lopes-Coelho F, Sequeira CO, Silva F, Gouveia-Fernandes S, Rodrigues A, Guimarães A, Silveira M, Abreu S, Santo VE, Brito C, Félix A, Pereira SA, Serpa J.

Sci Rep. 2018 Jun 22;8(1):9513. doi: 10.1038/s41598-018-27753-y.


Cysteine boosters the evolutionary adaptation to CoCl2 mimicked hypoxia conditions, favouring carboplatin resistance in ovarian cancer.

Nunes SC, Lopes-Coelho F, Gouveia-Fernandes S, Ramos C, Pereira SA, Serpa J.

BMC Evol Biol. 2018 Jun 19;18(1):97. doi: 10.1186/s12862-018-1214-1.


Improvement of neuronal differentiation by carbon monoxide: Role of pentose phosphate pathway.

Almeida AS, Soares NL, Sequeira CO, Pereira SA, Sonnewald U, Vieira HLA.

Redox Biol. 2018 Jul;17:338-347. doi: 10.1016/j.redox.2018.05.004. Epub 2018 May 15.


High resolution mass spectrometry-based methodologies for identification of Etravirine bioactivation to reactive metabolites: In vitro and in vivo approaches.

Godinho ALA, Martins IL, Nunes J, Charneira C, Grilo J, Silva DM, Pereira SA, Soto K, Oliveira MC, Marques MM, Jacob CC, Antunes AMM.

Eur J Pharm Sci. 2018 Jul 1;119:70-82. doi: 10.1016/j.ejps.2018.03.026. Epub 2018 Mar 26.


Usefulness of zebrafish larvae to evaluate drug-induced functional and morphological renal tubular alterations.

Gorgulho R, Jacinto R, Lopes SS, Pereira SA, Tranfield EM, Martins GG, Gualda EJ, Derks RJE, Correia AC, Steenvoorden E, Pintado P, Mayboroda OA, Monteiro EC, Morello J.

Arch Toxicol. 2018 Jan;92(1):411-423. doi: 10.1007/s00204-017-2063-1. Epub 2017 Sep 20.


Implications of sulfotransferase activity in interindividual variability in drug response: clinical perspective on current knowledge.

Marto N, Morello J, Monteiro EC, Pereira SA.

Drug Metab Rev. 2017 Aug;49(3):357-371. doi: 10.1080/03602532.2017.1335749. Epub 2017 Jun 20. Review.


Unmasking efavirenz neurotoxicity: Time matters to the underlying mechanisms.

Grilo NM, João Correia M, Miranda JP, Cipriano M, Serpa J, Matilde Marques M, Monteiro EC, Antunes AMM, Diogo LN, Pereira SA.

Eur J Pharm Sci. 2017 Jul 15;105:47-54. doi: 10.1016/j.ejps.2017.05.010. Epub 2017 May 6.


Efavirenz biotransformation as an up-stream event of mood changes in HIV-infected patients.

Grilo NM, Correia MJ, Sequeira C, Harjivan SG, Caixas U, Diogo LN, Marques MM, Monteiro EC, Antunes AM, Pereira SA.

Toxicol Lett. 2016 Oct 17;260:28-35. doi: 10.1016/j.toxlet.2016.08.009. Epub 2016 Aug 16.


Hepatocyte spheroids as a competent in vitro system for drug biotransformation studies: nevirapine as a bioactivation case study.

Pinheiro PF, Pereira SA, Harjivan SG, Martins IL, Marinho AT, Cipriano M, Jacob CC, Oliveira NG, Castro MF, Marques MM, Antunes AMM, Miranda JP.

Arch Toxicol. 2017 Mar;91(3):1199-1211. doi: 10.1007/s00204-016-1792-x. Epub 2016 Jul 14.


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