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  • Showing results for simone potent. Search instead for Simone Potenti (1 item)
1.

A novel class of multitarget anti-Alzheimer benzohomoadamantane‒chlorotacrine hybrids modulating cholinesterases and glutamate NMDA receptors.

Pérez-Areales FJ, Turcu AL, Barniol-Xicota M, Pont C, Pivetta D, Espargaró A, Bartolini M, De Simone A, Andrisano V, Pérez B, Sabate R, Sureda FX, Vázquez S, Muñoz-Torrero D.

Eur J Med Chem. 2019 Jul 17;180:613-626. doi: 10.1016/j.ejmech.2019.07.051. [Epub ahead of print]

PMID:
31351393
2.

Comprehensive Chemical Profiling and Multidirectional Biological Investigation of Two Wild Anthemis Species (Anthemis tinctoria var. Pallida and A. cretica subsp. tenuiloba): Focus on Neuroprotective Effects.

Orlando G, Zengin G, Ferrante C, Ronci M, Recinella L, Senkardes I, Gevrenova R, Zheleva-Dimitrova D, Chiavaroli A, Leone S, Di Simone S, Brunetti L, Picot-Allain CMN, Mahomoodally MF, Sinan KI, Menghini L.

Molecules. 2019 Jul 16;24(14). pii: E2582. doi: 10.3390/molecules24142582.

3.

Role of Platelet Glycoprotein VI and Tyrosine Kinase Syk in Thrombus Formation on Collagen-Like Surfaces.

Jooss NJ, De Simone I, Provenzale I, Fernández DI, Brouns SLN, Farndale RW, Henskens YMC, Kuijpers MJE, Ten Cate H, van der Meijden PEJ, Cavill R, Heemskerk JWM.

Int J Mol Sci. 2019 Jun 7;20(11). pii: E2788. doi: 10.3390/ijms20112788.

4.

Re-opening the stage for Echinacea research - Characterization of phylloxanthobilins as a novel anti-oxidative compound class in Echinacea purpurea.

Karg CA, Wang P, Vollmar AM, Moser S.

Phytomedicine. 2019 May 22:152969. doi: 10.1016/j.phymed.2019.152969. [Epub ahead of print]

PMID:
31153733
5.

The Up-Regulation of Oxidative Stress as a Potential Mechanism of Novel MAO-B Inhibitors for Glioblastoma Treatment.

Marconi GD, Gallorini M, Carradori S, Guglielmi P, Cataldi A, Zara S.

Molecules. 2019 May 25;24(10). pii: E2005. doi: 10.3390/molecules24102005.

6.

Liquid Phase and Microwave-Assisted Extractions for Multicomponent Phenolic Pattern Determination of Five Romanian Galium Species Coupled with Bioassays.

Mocan A, Diuzheva A, Bădărău S, Moldovan C, Andruch V, Carradori S, Campestre C, Tartaglia A, De Simone M, Vodnar D, Tiecco M, Germani R, Crișan G, Locatelli M.

Molecules. 2019 Mar 28;24(7). pii: E1226. doi: 10.3390/molecules24071226.

7.

A computationally designed binding mode flip leads to a novel class of potent tri-vector cyclophilin inhibitors.

De Simone A, Georgiou C, Ioannidis H, Gupta AA, Juárez-Jiménez J, Doughty-Shenton D, Blackburn EA, Wear MA, Richards JP, Barlow PN, Carragher N, Walkinshaw MD, Hulme AN, Michel J.

Chem Sci. 2018 Oct 23;10(2):542-547. doi: 10.1039/c8sc03831g. eCollection 2019 Jan 14.

8.

Bioactivity and Structural Properties of Novel Synthetic Analogues of the Protozoan Toxin Climacostol.

Buonanno F, Catalani E, Cervia D, Proietti Serafini F, Picchietti S, Fausto AM, Giorgi S, Lupidi G, Rossi FV, Marcantoni E, Petrelli D, Ortenzi C.

Toxins (Basel). 2019 Jan 15;11(1). pii: E42. doi: 10.3390/toxins11010042.

9.

Toxic Indole Diterpenes from Endophyte-Infected Perennial Ryegrass Lolium perenne L.: Isolation and Stability.

Reddy P, Deseo MA, Ezernieks V, Guthridge K, Spangenberg G, Rochfort S.

Toxins (Basel). 2019 Jan 3;11(1). pii: E16. doi: 10.3390/toxins11010016.

10.

Exploring structural properties of potent human carbonic anhydrase inhibitors bearing a 4-(cycloalkylamino-1-carbonyl)benzenesulfonamide moiety.

Buemi MR, Di Fiore A, De Luca L, Angeli A, Mancuso F, Ferro S, Monti SM, Buonanno M, Russo E, De Sarro G, De Simone G, Supuran CT, Gitto R.

Eur J Med Chem. 2019 Feb 1;163:443-452. doi: 10.1016/j.ejmech.2018.11.073. Epub 2018 Dec 1.

PMID:
30530195
11.

Antioxidant metabolism regulates CD8+ T memory stem cell formation and antitumor immunity.

Pilipow K, Scamardella E, Puccio S, Gautam S, De Paoli F, Mazza EM, De Simone G, Polletti S, Buccilli M, Zanon V, Di Lucia P, Iannacone M, Gattinoni L, Lugli E.

JCI Insight. 2018 Sep 20;3(18). pii: 122299. doi: 10.1172/jci.insight.122299. eCollection 2018 Sep 20.

12.

The Hydrophobin HYTLO1 Secreted by the Biocontrol Fungus Trichoderma longibrachiatum Triggers a NAADP-Mediated Calcium Signalling Pathway in Lotus japonicus.

Moscatiello R, Sello S, Ruocco M, Barbulova A, Cortese E, Nigris S, Baldan B, Chiurazzi M, Mariani P, Lorito M, Navazio L.

Int J Mol Sci. 2018 Sep 1;19(9). pii: E2596. doi: 10.3390/ijms19092596.

13.

MiRNAs: dynamic regulators of immune cell functions in inflammation and cancer.

Hirschberger S, Hinske LC, Kreth S.

Cancer Lett. 2018 Sep 1;431:11-21. doi: 10.1016/j.canlet.2018.05.020. Epub 2018 May 22.

14.

Are Carbonic Anhydrases Suitable Targets to Fight Protozoan Parasitic Diseases?

D'Ambrosio K, Supuran CT, De Simone G.

Curr Med Chem. 2018;25(39):5266-5278. doi: 10.2174/0929867325666180326160121. Review.

PMID:
29589529
15.

Bivalent ligand MCC22 potently attenuates nociception in a murine model of sickle cell disease.

Cataldo G, Lunzer MM, Olson JK, Akgün E, Belcher JD, Vercellotti GM, Portoghese PS, Simone DA.

Pain. 2018 Jul;159(7):1382-1391. doi: 10.1097/j.pain.0000000000001225.

16.

Amaryllidaceae Alkaloids as Potential Glycogen Synthase Kinase-3β Inhibitors.

Hulcová D, Breiterová K, Siatka T, Klímová K, Davani L, Šafratová M, Hošťálková A, De Simone A, Andrisano V, Cahlíková L.

Molecules. 2018 Mar 21;23(4). pii: E719. doi: 10.3390/molecules23040719.

17.

In vitro efficacy of ARQ 092, an allosteric AKT inhibitor, on primary fibroblast cells derived from patients with PIK3CA-related overgrowth spectrum (PROS).

Ranieri C, Di Tommaso S, Loconte DC, Grossi V, Sanese P, Bagnulo R, Susca FC, Forte G, Peserico A, De Luisi A, Bartuli A, Selicorni A, Melis D, Lerone M, Praticò AD, Abbadessa G, Yu Y, Schwartz B, Ruggieri M, Simone C, Resta N.

Neurogenetics. 2018 May;19(2):77-91. doi: 10.1007/s10048-018-0540-1. Epub 2018 Mar 16.

18.

Loss of BID Delays FASL-Induced Cell Death of Mouse Neutrophils and Aggravates DSS-Induced Weight Loss.

Wicki S, Gurzeler U, Corazza N, Genitsch V, Wong WW, Kaufmann T.

Int J Mol Sci. 2018 Feb 28;19(3). pii: E684. doi: 10.3390/ijms19030684.

19.

Minor Capsid Protein L2 Polytope Induces Broad Protection against Oncogenic and Mucosal Human Papillomaviruses.

Pouyanfard S, Spagnoli G, Bulli L, Balz K, Yang F, Odenwald C, Seitz H, Mariz FC, Bolchi A, Ottonello S, Müller M.

J Virol. 2018 Jan 30;92(4). pii: e01930-17. doi: 10.1128/JVI.01930-17. Print 2018 Feb 15.

20.

In-vitro blockade of the CD4 receptor co-signal in antigen-specific T-cell stimulation cultures induces the outgrowth of potent CD4 independent T-cell effectors.

Vatter S, Schmid M, Gebhard C, Mirbeth C, Klobuch S, Rehli M, Herr W, Thomas S.

J Immunol Methods. 2018 Mar;454:80-85. doi: 10.1016/j.jim.2017.11.006. Epub 2017 Nov 14.

PMID:
29154771

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