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Items: 1 to 20 of 42

1.

Chemistry and Pharmacology of GPBAR1 and FXR Selective Agonists, Dual Agonists, and Antagonists.

De Marino S, Festa C, Sepe V, Zampella A.

Handb Exp Pharmacol. 2019;256:137-165. doi: 10.1007/164_2019_237. Review.

PMID:
31201554
2.

Wound healing activity and phytochemical screening of purified fractions of Sempervivum tectorum L. leaves on HCT 116.

Cattaneo F, De Marino S, Parisi M, Festa C, Castaldo M, Finamore C, Duraturo F, Zollo C, Ammendola R, Zollo F, Iorizzi M.

Phytochem Anal. 2019 Sep;30(5):524-534. doi: 10.1002/pca.2844. Epub 2019 Jun 5.

PMID:
31168900
3.

Phytochemical and Biological Studies of Nepeta asterotricha Rech. f. (Lamiaceae): Isolation of Nepetamoside.

Goldansaz SM, Festa C, Pagano E, De Marino S, Finamore C, Parisi OA, Borrelli F, Sonboli A, D'Auria MV.

Molecules. 2019 Apr 30;24(9). pii: E1684. doi: 10.3390/molecules24091684.

4.

Investigation around the Oxadiazole Core in the Discovery of a New Chemotype of Potent and Selective FXR Antagonists.

Festa C, Finamore C, Marchianò S, Di Leva FS, Carino A, Monti MC, Del Gaudio F, Ceccacci S, Limongelli V, Zampella A, Fiorucci S, De Marino S.

ACS Med Chem Lett. 2019 Jan 10;10(4):504-510. doi: 10.1021/acsmedchemlett.8b00534. eCollection 2019 Apr 11.

PMID:
30996787
5.

Discovery of ((1,2,4-oxadiazol-5-yl)pyrrolidin-3-yl)ureidyl derivatives as selective non-steroidal agonists of the G-protein coupled bile acid receptor-1.

Di Leva FS, Festa C, Carino A, De Marino S, Marchianò S, Di Marino D, Finamore C, Monti MC, Zampella A, Fiorucci S, Limongelli V.

Sci Rep. 2019 Feb 21;9(1):2504. doi: 10.1038/s41598-019-38840-z.

6.

Targeting Bile Acid Receptors: Discovery of a Potent and Selective Farnesoid X Receptor Agonist as a New Lead in the Pharmacological Approach to Liver Diseases.

Festa C, De Marino S, Carino A, Sepe V, Marchianò S, Cipriani S, Di Leva FS, Limongelli V, Monti MC, Capolupo A, Distrutti E, Fiorucci S, Zampella A.

Front Pharmacol. 2017 Mar 30;8:162. doi: 10.3389/fphar.2017.00162. eCollection 2017.

7.

Hyodeoxycholic acid derivatives as liver X receptor α and G-protein-coupled bile acid receptor agonists.

De Marino S, Carino A, Masullo D, Finamore C, Marchianò S, Cipriani S, Di Leva FS, Catalanotti B, Novellino E, Limongelli V, Fiorucci S, Zampella A.

Sci Rep. 2017 Feb 24;7:43290. doi: 10.1038/srep43290.

8.

Biomolecular proteomics discloses ATP synthase as the main target of the natural glycoside deglucoruscin.

Del Gaudio F, Festa C, Mozzicafreddo M, Vasaturo M, Casapullo A, De Marino S, Riccio R, Monti MC.

Mol Biosyst. 2016 Oct 20;12(10):3132-8. doi: 10.1039/c6mb00460a. Epub 2016 Aug 1.

PMID:
27476482
9.

Anti-inflammatory and analgesic activities with gastroprotective effect of semi-purified fractions and isolation of pure compounds from Mediterranean gorgonian Eunicella singularis.

Deghrigue M, Festa C, Ghribi L, D'Auria MV, De Marino S, Ben Jannet H, Bouraoui A.

Asian Pac J Trop Med. 2015 Aug;8(8):606-11. doi: 10.1016/j.apjtm.2015.07.019. Epub 2015 Jul 23.

10.

Molecular decodification of gymnemic acids from Gymnema sylvestre. Discovery of a new class of liver X receptor antagonists.

Renga B, Festa C, De Marino S, Di Micco S, D'Auria MV, Bifulco G, Fiorucci S, Zampella A.

Steroids. 2015 Apr;96:121-31. doi: 10.1016/j.steroids.2015.01.024. Epub 2015 Feb 7.

PMID:
25668616
11.

Scalarane sesterterpenes from Thorectidae sponges as inhibitors of TDP-43 nuclear factor.

Festa C, Cassiano C, D'Auria MV, Debitus C, Monti MC, De Marino S.

Org Biomol Chem. 2014 Nov 21;12(43):8646-55. doi: 10.1039/c4ob01510j.

PMID:
25251727
12.

Exploitation of cholane scaffold for the discovery of potent and selective farnesoid X receptor (FXR) and G-protein coupled bile acid receptor 1 (GP-BAR1) ligands.

Festa C, Renga B, D'Amore C, Sepe V, Finamore C, De Marino S, Carino A, Cipriani S, Monti MC, Zampella A, Fiorucci S.

J Med Chem. 2014 Oct 23;57(20):8477-95. doi: 10.1021/jm501273r. Epub 2014 Oct 9.

PMID:
25247751
13.

Pharmacological evaluation of the semi-purified fractions from the soft coral Eunicella singularis and isolation of pure compounds.

Deghrigue M, Festa C, Ghribi L, D'auria MV, de Marino S, Ben Jannet H, Ben Said R, Bouraoui A.

Daru. 2014 Sep 10;22:64. doi: 10.1186/s40199-014-0064-7.

14.

Antioxidant activity and chemical components as potential anticancer agents in the olive leaf (Olea europaea L. cv Leccino.) decoction.

De Marino S, Festa C, Zollo F, Nini A, Antenucci L, Raimo G, Iorizzi M.

Anticancer Agents Med Chem. 2014;14(10):1376-85.

PMID:
25102361
15.

Bioactive cembrane derivatives from the Indian Ocean soft coral, Sinularia kavarattiensis.

Lillsunde KE, Festa C, Adel H, De Marino S, Lombardi V, Tilvi S, Nawrot DA, Zampella A, D'Souza L, D'Auria MV, Tammela P.

Mar Drugs. 2014 Jul 3;12(7):4045-68. doi: 10.3390/md12074045.

16.

Marine and semi-synthetic hydroxysteroids as new scaffolds for pregnane X receptor modulation.

Sepe V, Di Leva FS, D'Amore C, Festa C, De Marino S, Renga B, D'Auria MV, Novellino E, Limongelli V, D'Souza L, Majik M, Zampella A, Fiorucci S.

Mar Drugs. 2014 May 27;12(6):3091-115. doi: 10.3390/md12063091.

17.

Plakilactones G and H from a marine sponge. Stereochemical determination of highly flexible systems by quantitative NMR-derived interproton distances combined with quantum mechanical calculations of (13)C chemical shifts.

Di Micco S, Zampella A, D'Auria MV, Festa C, De Marino S, Riccio R, Butts CP, Bifulco G.

Beilstein J Org Chem. 2013 Dec 30;9:2940-9. doi: 10.3762/bjoc.9.331. eCollection 2013 Dec 30.

18.

Oxygenated polyketides from Plakinastrella mamillaris as a new chemotype of PXR agonists.

Festa C, D'Amore C, Renga B, Lauro G, De Marino S, D'Auria MV, Bifulco G, Zampella A, Fiorucci S.

Mar Drugs. 2013 Jul 2;11(7):2314-27. doi: 10.3390/md11072314.

19.

Binding mechanism of the farnesoid X receptor marine antagonist suvanine reveals a strategy to forestall drug modulation on nuclear receptors. Design, synthesis, and biological evaluation of novel ligands.

Di Leva FS, Festa C, D'Amore C, De Marino S, Renga B, D'Auria MV, Novellino E, Limongelli V, Zampella A, Fiorucci S.

J Med Chem. 2013 Jun 13;56(11):4701-17. doi: 10.1021/jm400419e. Epub 2013 May 24.

PMID:
23656455
20.

Differential in gel electrophoresis (DIGE) comparative proteomic analysis of macrophages cell cultures in response to perthamide C treatment.

Vilasi A, Monti MC, Tosco A, De Marino S, Margarucci L, Riccio R, Casapullo A.

Mar Drugs. 2013 Apr 17;11(4):1288-99. doi: 10.3390/md11041288.

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