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Items: 18


High Risk of Hepatocellular Carcinoma Development in Fibrotic Liver: Role of the Hippo-YAP/TAZ Signaling Pathway.

Moon H, Cho K, Shin S, Kim DY, Han KH, Ro SW.

Int J Mol Sci. 2019 Jan 29;20(3). pii: E581. doi: 10.3390/ijms20030581. Review.


Barrier to autointegration factor 1, procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3, and splicing factor 3b subunit 4 as early-stage cancer decision markers and drivers of hepatocellular carcinoma.

Shen Q, Eun JW, Lee K, Kim HS, Yang HD, Kim SY, Lee EK, Kim T, Kang K, Kim S, Min DH, Oh SN, Lee YJ, Moon H, Ro SW, Park WS, Lee JY, Nam SW.

Hepatology. 2018 Apr;67(4):1360-1377. doi: 10.1002/hep.29606. Epub 2018 Feb 20. Erratum in: Hepatology. 2018 Jul;68(1):391.


Transforming Growth Factor-β Promotes Liver Tumorigenesis in Mice via Up-regulation of Snail.

Moon H, Ju HL, Chung SI, Cho KJ, Eun JW, Nam SW, Han KH, Calvisi DF, Ro SW.

Gastroenterology. 2017 Nov;153(5):1378-1391.e6. doi: 10.1053/j.gastro.2017.07.014. Epub 2017 Jul 20.


Deubiquitinase YOD1 potentiates YAP/TAZ activities through enhancing ITCH stability.

Kim Y, Kim W, Song Y, Kim JR, Cho K, Moon H, Ro SW, Seo E, Ryu YM, Myung SJ, Jho EH.

Proc Natl Acad Sci U S A. 2017 May 2;114(18):4691-4696. doi: 10.1073/pnas.1620306114. Epub 2017 Apr 17.


Making cancer fat: reprogramming of lipid metabolism by CD147 in hepatocellular carcinoma.

Ju HL, Ro SW.

Chin J Cancer Res. 2016 Jun;28(3):380-2. doi: 10.21147/j.issn.1000-9604.2016.03.14. No abstract available.


Development of a transgenic mouse model of hepatocellular carcinoma with a liver fibrosis background.

Chung SI, Moon H, Kim DY, Cho KJ, Ju HL, Kim DY, Ahn SH, Han KH, Ro SW.

BMC Gastroenterol. 2016 Jan 29;16:13. doi: 10.1186/s12876-016-0423-6.


Comparison of liver oncogenic potential among human RAS isoforms.

Chung SI, Moon H, Ju HL, Kim DY, Cho KJ, Ribback S, Dombrowski F, Calvisi DF, Ro SW.

Oncotarget. 2016 Feb 9;7(6):7354-66. doi: 10.18632/oncotarget.6931.


Hepatic expression of Sonic Hedgehog induces liver fibrosis and promotes hepatocarcinogenesis in a transgenic mouse model.

Chung SI, Moon H, Ju HL, Cho KJ, Kim DY, Han KH, Eun JW, Nam SW, Ribback S, Dombrowski F, Calvisi DF, Ro SW.

J Hepatol. 2016 Mar;64(3):618-27. doi: 10.1016/j.jhep.2015.10.007. Epub 2015 Oct 22.


Transgenic mouse models generated by hydrodynamic transfection for genetic studies of liver cancer and preclinical testing of anti-cancer therapy.

Ju HL, Han KH, Lee JD, Ro SW.

Int J Cancer. 2016 Apr 1;138(7):1601-8. doi: 10.1002/ijc.29703. Epub 2015 Aug 7. Review.


Efficacy of perifosine alone and in combination with sorafenib in an HrasG12V plus shp53 transgenic mouse model of hepatocellular carcinoma.

Kim MN, Ro SW, Kim DY, Kim da Y, Cho KJ, Park JH, Lim HY, Han KH.

Cancer Chemother Pharmacol. 2015 Aug;76(2):257-67. doi: 10.1007/s00280-015-2787-7. Epub 2015 Jun 3.


Synergic chemoprevention with dietary carbohydrate restriction and supplementation of AMPK-activating phytochemicals: the role of SIRT1.

Lee JD, Choi MA, Ro SW, Yang WI, Cho AE, Ju HL, Baek S, Chung SI, Kang WJ, Yun M, Park JH.

Eur J Cancer Prev. 2016 Jan;25(1):54-64. doi: 10.1097/CEJ.0000000000000141.


Analysis of miRNA expression patterns in human and mouse hepatocellular carcinoma cells.

Baek S, Cho KJ, Ju HL, Moon H, Choi SH, Chung SI, Park JY, Choi KH, Kim DY, Ahn SH, Han KH, Ro SW.

Hepatol Res. 2015 Dec;45(13):1331-40. doi: 10.1111/hepr.12510. Epub 2015 Apr 7.


Transgenic mouse model expressing P53(R172H), luciferase, EGFP, and KRAS(G12D) in a single open reading frame for live imaging of tumor.

Ju HL, Calvisi DF, Moon H, Baek S, Ribback S, Dombrowski F, Cho KJ, Chung SI, Han KH, Ro SW.

Sci Rep. 2015 Jan 27;5:8053. doi: 10.1038/srep08053.


Inhibition of tumour angiogenesis and growth by small hairpin HIF-1α and IL-8 in hepatocellular carcinoma.

Choi SH, Kwon OJ, Park JY, Kim DY, Ahn SH, Kim SU, Ro SW, Kim KS, Park JH, Kim S, Yun CO, Han KH.

Liver Int. 2014 Apr;34(4):632-42. doi: 10.1111/liv.12375. Epub 2013 Dec 9.


Combined effects of an antioxidant and caspase inhibitor on the reversal of hepatic fibrosis in rats.

Kim DY, Chung SI, Ro SW, Paik YH, Lee JI, Jung MK, Lee MG, Park YN, Lee KS, Park JG, Park HD, Han KH.

Apoptosis. 2013 Dec;18(12):1481-91. doi: 10.1007/s10495-013-0896-5.


Investigation of oncogenic cooperation in simple liver-specific transgenic mouse models using noninvasive in vivo imaging.

Ju HL, Ahn SH, Kim DY, Baek S, Chung SI, Seong J, Han KH, Ro SW.

PLoS One. 2013;8(3):e59869. doi: 10.1371/journal.pone.0059869. Epub 2013 Mar 28.


Sleeping Beauty transposon system harboring HRAS, c-Myc and shp53 induces sarcomatoid carcinomas in mouse skin.

Jung S, Ro SW, Jung G, Ju HL, Yu ES, Son WC.

Oncol Rep. 2013 Apr;29(4):1293-8. doi: 10.3892/or.2013.2264. Epub 2013 Jan 31.

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