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Items: 1 to 20 of 23

1.

Mining the Plasma Cell Transcriptome for Novel Cell Surface Proteins.

Trezise S, Karnowski A, Fedele PL, Mithraprabhu S, Liao Y, D'Costa K, Kueh AJ, Hardy MP, Owczarek CM, Herold MJ, Spencer A, Shi W, Willis SN, Nutt SL, Corcoran LM.

Int J Mol Sci. 2018 Jul 24;19(8). pii: E2161. doi: 10.3390/ijms19082161.

2.

Environmental sensing by mature B cells is controlled by the transcription factors PU.1 and SpiB.

Willis SN, Tellier J, Liao Y, Trezise S, Light A, O'Donnell K, Garrett-Sinha LA, Shi W, Tarlinton DM, Nutt SL.

Nat Commun. 2017 Nov 10;8(1):1426. doi: 10.1038/s41467-017-01605-1.

3.

NFκB1 is essential to prevent the development of multiorgan autoimmunity by limiting IL-6 production in follicular B cells.

de Valle E, Grigoriadis G, O'Reilly LA, Willis SN, Maxwell MJ, Corcoran LM, Tsantikos E, Cornish JK, Fairfax KA, Vasanthakumar A, Febbraio MA, Hibbs ML, Pellegrini M, Banerjee A, Hodgkin PD, Kallies A, Mackay F, Strasser A, Gerondakis S, Gugasyan R.

J Exp Med. 2016 Apr 4;213(4):621-41. doi: 10.1084/jem.20151182. Epub 2016 Mar 28.

4.

Investigating the Antigen Specificity of Multiple Sclerosis Central Nervous System-Derived Immunoglobulins.

Willis SN, Stathopoulos P, Chastre A, Compton SD, Hafler DA, O'Connor KC.

Front Immunol. 2015 Nov 25;6:600. doi: 10.3389/fimmu.2015.00600. eCollection 2015.

5.

Transcriptional profiling of mouse B cell terminal differentiation defines a signature for antibody-secreting plasma cells.

Shi W, Liao Y, Willis SN, Taubenheim N, Inouye M, Tarlinton DM, Smyth GK, Hodgkin PD, Nutt SL, Corcoran LM.

Nat Immunol. 2015 Jun;16(6):663-73. doi: 10.1038/ni.3154. Epub 2015 Apr 20.

PMID:
25894659
6.

The transcription factors IRF8 and PU.1 negatively regulate plasma cell differentiation.

Carotta S, Willis SN, Hasbold J, Inouye M, Pang SH, Emslie D, Light A, Chopin M, Shi W, Wang H, Morse HC 3rd, Tarlinton DM, Corcoran LM, Hodgkin PD, Nutt SL.

J Exp Med. 2014 Oct 20;211(11):2169-81. doi: 10.1084/jem.20140425. Epub 2014 Oct 6.

7.

Transcription factor IRF4 regulates germinal center cell formation through a B cell-intrinsic mechanism.

Willis SN, Good-Jacobson KL, Curtis J, Light A, Tellier J, Shi W, Smyth GK, Tarlinton DM, Belz GT, Corcoran LM, Kallies A, Nutt SL.

J Immunol. 2014 Apr 1;192(7):3200-6. doi: 10.4049/jimmunol.1303216. Epub 2014 Mar 3.

8.

Protein array-based profiling of CSF identifies RBPJ as an autoantigen in multiple sclerosis.

Querol L, Clark PL, Bailey MA, Cotsapas C, Cross AH, Hafler DA, Kleinstein SH, Lee JY, Yaari G, Willis SN, O'Connor KC.

Neurology. 2013 Sep 10;81(11):956-63. doi: 10.1212/WNL.0b013e3182a43b48. Epub 2013 Aug 6.

9.

Autoantibodies produced at the site of tissue damage provide evidence of humoral autoimmunity in inclusion body myositis.

Ray A, Amato AA, Bradshaw EM, Felice KJ, DiCapua DB, Goldstein JM, Lundberg IE, Nowak RJ, Ploegh HL, Spooner E, Wu Q, Willis SN, O'Connor KC.

PLoS One. 2012;7(10):e46709. doi: 10.1371/journal.pone.0046709. Epub 2012 Oct 5.

10.

Related B cell clones that populate the CSF and CNS of patients with multiple sclerosis produce CSF immunoglobulin.

Obermeier B, Lovato L, Mentele R, Brück W, Forne I, Imhof A, Lottspeich F, Turk KW, Willis SN, Wekerle H, Hohlfeld R, Hafler DA, O'Connor KC, Dornmair K.

J Neuroimmunol. 2011 Apr;233(1-2):245-8. doi: 10.1016/j.jneuroim.2011.01.010. Epub 2011 Feb 24.

11.

Related B cell clones populate the meninges and parenchyma of patients with multiple sclerosis.

Lovato L, Willis SN, Rodig SJ, Caron T, Almendinger SE, Howell OW, Reynolds R, O'Connor KC, Hafler DA.

Brain. 2011 Feb;134(Pt 2):534-41. doi: 10.1093/brain/awq350. Epub 2011 Jan 7.

12.

Structural basis for apoptosis inhibition by Epstein-Barr virus BHRF1.

Kvansakul M, Wei AH, Fletcher JI, Willis SN, Chen L, Roberts AW, Huang DC, Colman PM.

PLoS Pathog. 2010 Dec 23;6(12):e1001236. doi: 10.1371/journal.ppat.1001236.

13.

Epstein-Barr virus infection is not a characteristic feature of multiple sclerosis brain.

Willis SN, Stadelmann C, Rodig SJ, Caron T, Gattenloehner S, Mallozzi SS, Roughan JE, Almendinger SE, Blewett MM, Brück W, Hafler DA, O'Connor KC.

Brain. 2009 Dec;132(Pt 12):3318-28. doi: 10.1093/brain/awp200.

14.

The microenvironment of germ cell tumors harbors a prominent antigen-driven humoral response.

Willis SN, Mallozzi SS, Rodig SJ, Cronk KM, McArdel SL, Caron T, Pinkus GS, Lovato L, Shampain KL, Anderson DE, Anderson RC, Bruce JN, O'Connor KC.

J Immunol. 2009 Mar 1;182(5):3310-7. doi: 10.4049/jimmunol.0803424.

15.

A novel BH3 ligand that selectively targets Mcl-1 reveals that apoptosis can proceed without Mcl-1 degradation.

Lee EF, Czabotar PE, van Delft MF, Michalak EM, Boyle MJ, Willis SN, Puthalakath H, Bouillet P, Colman PM, Huang DC, Fairlie WD.

J Cell Biol. 2008 Jan 28;180(2):341-55. doi: 10.1083/jcb.200708096. Epub 2008 Jan 21.

16.

Immune surveillance of intracranial germ cell tumors.

Willis SN, Mallozzi SS, O'Connor KC.

MedLab Mag. 2008;(2):14-15. No abstract available.

17.

Interleukin 15-mediated survival of natural killer cells is determined by interactions among Bim, Noxa and Mcl-1.

Huntington ND, Puthalakath H, Gunn P, Naik E, Michalak EM, Smyth MJ, Tabarias H, Degli-Esposti MA, Dewson G, Willis SN, Motoyama N, Huang DC, Nutt SL, Tarlinton DM, Strasser A.

Nat Immunol. 2007 Aug;8(8):856-63. Epub 2007 Jul 8.

18.

Apoptosis initiated when BH3 ligands engage multiple Bcl-2 homologs, not Bax or Bak.

Willis SN, Fletcher JI, Kaufmann T, van Delft MF, Chen L, Czabotar PE, Ierino H, Lee EF, Fairlie WD, Bouillet P, Strasser A, Kluck RM, Adams JM, Huang DC.

Science. 2007 Feb 9;315(5813):856-9.

19.

The BH3 mimetic ABT-737 targets selective Bcl-2 proteins and efficiently induces apoptosis via Bak/Bax if Mcl-1 is neutralized.

van Delft MF, Wei AH, Mason KD, Vandenberg CJ, Chen L, Czabotar PE, Willis SN, Scott CL, Day CL, Cory S, Adams JM, Roberts AW, Huang DC.

Cancer Cell. 2006 Nov;10(5):389-99.

20.

CD45 links the B cell receptor with cell survival and is required for the persistence of germinal centers.

Huntington ND, Xu Y, Puthalakath H, Light A, Willis SN, Strasser A, Tarlinton DM.

Nat Immunol. 2006 Feb;7(2):190-8. Epub 2005 Dec 25.

PMID:
16378097

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