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Items: 1 to 20 of 37

1.

Therapeutic Perspective of Vitamin C and Its Derivatives.

Meščić Macan A, Gazivoda Kraljević T, Raić-Malić S.

Antioxidants (Basel). 2019 Jul 26;8(8). pii: E247. doi: 10.3390/antiox8080247. Review.

2.

Synthesis, anti-bacterial and anti-protozoal activities of amidinobenzimidazole derivatives and their interactions with DNA and RNA.

Bistrović A, Krstulović L, Stolić I, Drenjančević D, Talapko J, Taylor MC, Kelly JM, Bajić M, Raić-Malić S.

J Enzyme Inhib Med Chem. 2018 Dec;33(1):1323-1334. doi: 10.1080/14756366.2018.1484733.

3.

Small molecule purine and pseudopurine derivatives: synthesis, cytostatic evaluations and investigation of growth inhibitory effect in non-small cell lung cancer A549.

Bistrović A, Grbčić P, Harej A, Sedić M, Kraljević-Pavelić S, Koštrun S, Plavec J, Makuc D, Raić-Malić S.

J Enzyme Inhib Med Chem. 2018 Dec;33(1):271-285. doi: 10.1080/14756366.2017.1414807.

4.

Solvent-free copper-catalyzed click chemistry for the synthesis of N-heterocyclic hybrids based on quinoline and 1,2,3-triazole.

Tireli M, Maračić S, Lukin S, Kulcsár MJ, Žilić D, Cetina M, Halasz I, Raić-Malić S, Užarević K.

Beilstein J Org Chem. 2017 Nov 6;13:2352-2363. doi: 10.3762/bjoc.13.232. eCollection 2017.

5.

Design, synthesis and biological evaluation of novel benzimidazole amidines as potent multi-target inhibitors for the treatment of non-small cell lung cancer.

Bistrović A, Krstulović L, Harej A, Grbčić P, Sedić M, Koštrun S, Pavelić SK, Bajić M, Raić-Malić S.

Eur J Med Chem. 2018 Jan 1;143:1616-1634. doi: 10.1016/j.ejmech.2017.10.061. Epub 2017 Nov 11.

PMID:
29133046
6.

Synthesis and Anti-Proliferative Effects of Mono- and Bis-Purinomimetics Targeting Kinases.

Bistrović A, Harej A, Grbčić P, Sedić M, Kraljević Pavelić S, Cetina M, Raić-Malić S.

Int J Mol Sci. 2017 Nov 1;18(11). pii: E2292. doi: 10.3390/ijms18112292.

7.

Novel pyrimidine-2,4-dione-1,2,3-triazole and furo[2,3-d]pyrimidine-2-one-1,2,3-triazole hybrids as potential anti-cancer agents: Synthesis, computational and X-ray analysis and biological evaluation.

Gregorić T, Sedić M, Grbčić P, Tomljenović Paravić A, Kraljević Pavelić S, Cetina M, Vianello R, Raić-Malić S.

Eur J Med Chem. 2017 Jan 5;125:1247-1267. doi: 10.1016/j.ejmech.2016.11.028. Epub 2016 Nov 14.

PMID:
27875779
8.

Synthesis, in vitro anticancer and antibacterial activities and in silico studies of new 4-substituted 1,2,3-triazole-coumarin hybrids.

Kraljević TG, Harej A, Sedić M, Pavelić SK, Stepanić V, Drenjančević D, Talapko J, Raić-Malić S.

Eur J Med Chem. 2016 Nov 29;124:794-808. doi: 10.1016/j.ejmech.2016.08.062. Epub 2016 Aug 31.

PMID:
27639370
9.

Discovery of New Acid Ceramidase-Targeted Acyclic 5-Alkynyl and 5-Heteroaryl Uracil Nucleosides.

Meščić A, Harej A, Klobučar M, Glavač D, Cetina M, Pavelić SK, Raić-Malić S.

ACS Med Chem Lett. 2015 Oct 5;6(11):1150-5. doi: 10.1021/acsmedchemlett.5b00298. eCollection 2015 Nov 12.

10.

1,2,3-Triazole pharmacophore-based benzofused nitrogen/sulfur heterocycles with potential anti-Moraxella catarrhalis activity.

Maračić S, Kraljević TG, Paljetak HČ, Perić M, Matijašić M, Verbanac D, Cetina M, Raić-Malić S.

Bioorg Med Chem. 2015 Dec 1;23(23):7448-63. doi: 10.1016/j.bmc.2015.10.042. Epub 2015 Oct 30.

PMID:
26578325
11.

Recent trends in 1,2,3-Triazolo-nucleosides as promising anti-infective and anticancer agents.

Raic-Malic S, Mescic A.

Curr Med Chem. 2015;22(12):1462-99. Review.

PMID:
25723510
12.

Synthesis and in vitro antiproliferative evaluation of novel N-alkylated 6-isobutyl- and propyl pyrimidine derivatives.

Gazivoda Kraljević T, Ilić N, Stepanić V, Sappe L, Petranović J, Kraljević Pavelić S, Raić-Malić S.

Bioorg Med Chem Lett. 2014 Jul 1;24(13):2913-7. doi: 10.1016/j.bmcl.2014.04.079. Epub 2014 Apr 30.

PMID:
24835982
13.

Synthesis and biological evaluation of a new acyclic pyrimidine derivative as a probe for imaging herpes simplex virus type 1 thymidine kinase gene expression.

Meščić A, Betzel T, Müller A, Slavik R, Cermak S, Raić-Malić S, Ametamey SM.

Molecules. 2013 Jul 19;18(7):8535-49. doi: 10.3390/molecules18078535.

14.

C-5 hydroxyethyl and hydroxypropyl acyclonucleosides as substrates for thymidine kinase of herpes simplex virus type 1 (HSV-1 TK): syntheses and biological evaluation.

Meščić A, Krištafor S, Novaković I, Osmanović A, Müller U, Završnik D, Ametamey SM, Scapozza L, Raić-Malić S.

Molecules. 2013 May 2;18(5):5104-24. doi: 10.3390/molecules18055104.

15.

Synthesis, cytostatic activity and ADME properties of C-5 substituted and N-acyclic pyrimidine derivatives.

Kraljević TG, Klika M, Kralj M, Martin-Kleiner I, Jurmanović S, Milić A, Padovan J, Raić-Malić S.

Bioorg Med Chem Lett. 2012 Jan 1;22(1):308-12. doi: 10.1016/j.bmcl.2011.11.009. Epub 2011 Nov 10.

PMID:
22130132
16.

Synthesis and evaluation of a C-6 alkylated pyrimidine derivative for the in vivo imaging of HSV1-TK gene expression.

Müller U, Martić M, Kraljević TG, Krištafor S, Ross TL, Ranadheera C, Müller A, Born M, Krämer SD, Raić-Malić S, Ametamey SM.

Nucl Med Biol. 2012 Feb;39(2):235-46. doi: 10.1016/j.nucmedbio.2011.07.009. Epub 2011 Sep 29.

PMID:
21958846
17.

A new N-methyl thymine derivative comprising a dihydroxyisobutenyl unit as ligand for thymidine kinase of herpes simplex virus type 1 (HSV-1 TK).

Krištafor S, Novaković I, Gazivoda Kraljević T, Kraljević Pavelić S, Lučin P, Westermaier Y, Pernot L, Scapozza L, Ametamey SM, Raić-Malić S.

Bioorg Med Chem Lett. 2011 Oct 15;21(20):6161-5. doi: 10.1016/j.bmcl.2011.07.115. Epub 2011 Aug 6.

PMID:
21911293
18.

Methoxymethyl (MOM) group nitrogen protection of pyrimidines bearing C-6 acyclic side-chains.

Kraljević TG, Petrović M, Krištafor S, Makuc D, Plavec J, Ross TL, Ametamey SM, Raić-Malić S.

Molecules. 2011 Jun 20;16(6):5113-29. doi: 10.3390/molecules16065113.

19.

Synthesis, crystal structure, and in vitro biological evaluation of C-6 pyrimidine derivatives: new lead structures for monitoring gene expression in vivo.

Martić M, Pernot L, Westermaier Y, Perozzo R, Kraljević TG, Krištafor S, Raić-Malić S, Scapozza L, Ametamey S.

Nucleosides Nucleotides Nucleic Acids. 2011 Apr;30(4):293-315. doi: 10.1080/15257770.2011.581258.

PMID:
21623543
20.

Synthesis, X-ray crystal structure study and antitumoral evaluations of 5,6-disubstituted pyrimidine derivatives.

Kraljević TG, Kristafor S, Suman L, Kralj M, Ametamey SM, Cetina M, Raić-Malić S.

Bioorg Med Chem. 2010 Apr 1;18(7):2704-12. doi: 10.1016/j.bmc.2010.02.023. Epub 2010 Feb 18.

PMID:
20211564

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