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Items: 18

1.

In-Plane Mechanical Behavior of a New Star-Re-Entrant Hierarchical Metamaterial.

Zhang W, Zhao S, Sun R, Scarpa F, Wang J.

Polymers (Basel). 2019 Jul 3;11(7). pii: E1132. doi: 10.3390/polym11071132.

2.

Discovery of a GPR40 Superagonist: The Impact of Aryl Propionic Acid α-Fluorination.

Huang H, Meegalla SK, Lanter JC, Winters MP, Zhao S, Littrell J, Qi J, Rady B, Lee PS, Liu J, Martin T, Lam WW, Xu F, Lim HK, Wilde T, Silva J, Otieno M, Pocai A, Player MR.

ACS Med Chem Lett. 2018 Dec 3;10(1):16-21. doi: 10.1021/acsmedchemlett.8b00444. eCollection 2019 Jan 10.

PMID:
30655940
3.

IL-17A/IL-17RA promotes invasion and activates MMP-2 and MMP-9 expression via p38 MAPK signaling pathway in non-small cell lung cancer.

Wu Z, He D, Zhao S, Wang H.

Mol Cell Biochem. 2019 May;455(1-2):195-206. doi: 10.1007/s11010-018-3483-9. Epub 2018 Dec 18.

PMID:
30564960
4.

6-Benzhydryl-4-amino-quinolin-2-ones as Potent Cannabinoid Type 1 (CB1) Receptor Inverse Agonists and Chemical Modifications for Peripheral Selectivity.

Zhang YM, Greco MN, Macielag MJ, Teleha CA, DesJarlais RL, Tang Y, Ho G, Hou C, Chen C, Zhao S, Kauffman J, Camacho R, Qi J, Murray W, Demarest K, Leonard J.

J Med Chem. 2018 Nov 21;61(22):10276-10298. doi: 10.1021/acs.jmedchem.8b01467. Epub 2018 Oct 31.

PMID:
30339387
5.

GPR40-Mediated Gα12 Activation by Allosteric Full Agonists Highly Efficacious at Potentiating Glucose-Stimulated Insulin Secretion in Human Islets.

Rives ML, Rady B, Swanson N, Zhao S, Qi J, Arnoult E, Bakaj I, Mancini A, Breton B, Lee SP, Player MR, Pocai A.

Mol Pharmacol. 2018 Jun;93(6):581-591. doi: 10.1124/mol.117.111369. Epub 2018 Mar 23.

PMID:
29572336
6.

Discovery of a novel potent GPR40 full agonist.

Meegalla SK, Huang H, Martin T, Xu J, Zhao S, Liu J, Hall M, Gunnet J, Wang Y, Rady B, Silva J, Otieno M, Arnoult E, Paul Lee S, Pocai A, Player MR.

Bioorg Med Chem Lett. 2018 Feb 15;28(4):720-726. doi: 10.1016/j.bmcl.2018.01.013. Epub 2018 Jan 12.

PMID:
29366647
7.

Discovery of novel benzo[b]thiophene tetrazoles as non-carboxylate GPR40 agonists.

Huang H, Winters MP, Meegalla SK, Arnoult E, Paul Lee S, Zhao S, Martin T, Rady B, Liu J, Towers M, Otieno M, Xu F, Lim HK, Silva J, Pocai A, Player MR.

Bioorg Med Chem Lett. 2018 Feb 1;28(3):429-436. doi: 10.1016/j.bmcl.2017.12.022. Epub 2017 Dec 12.

PMID:
29258772
8.

Effects of p38MAPK-mediated excision repair cross-complementation 1 expression on prognosis of patients with non-small cell lung cancer.

He D, Ma X, Wu Z, Wang Y, Zhao S, Han F, Sun W.

Oncol Lett. 2017 Sep;14(3):3463-3472. doi: 10.3892/ol.2017.6649. Epub 2017 Jul 21.

9.

Carbon nanotubes kirigami mechanical metamaterials.

Zhao Y, Wang C, Wu J, Sui C, Zhao S, Zhang Z, He X.

Phys Chem Chem Phys. 2017 May 10;19(18):11032-11042. doi: 10.1039/c7cp00312a.

PMID:
28352879
10.
11.

Manipulation and formation mechanism of silica one-dimensional periodic structures by roller electrospinning.

Yao Y, Yin W, Cao J, Yang M, Li J, Zhao S, Li Y, He X, Leng J.

Langmuir. 2014 Mar 11;30(9):2335-45. doi: 10.1021/la4037277. Epub 2014 Feb 24.

PMID:
24528131
12.

Carboxylic acid bioisosteres acylsulfonamides, acylsulfamides, and sulfonylureas as novel antagonists of the CXCR2 receptor.

Winters MP, Crysler C, Subasinghe N, Ryan D, Leong L, Zhao S, Donatelli R, Yurkow E, Mazzulla M, Boczon L, Manthey CL, Molloy C, Raymond H, Murray L, McAlonan L, Tomczuk B.

Bioorg Med Chem Lett. 2008 Mar 15;18(6):1926-30. doi: 10.1016/j.bmcl.2008.01.127. Epub 2008 Feb 7.

PMID:
18308567
13.

Novel 1,4-benzodiazepine-2,5-diones as Hdm2 antagonists with improved cellular activity.

Leonard K, Marugan JJ, Raboisson P, Calvo R, Gushue JM, Koblish HK, Lattanze J, Zhao S, Cummings MD, Player MR, Maroney AC, Lu T.

Bioorg Med Chem Lett. 2006 Jul 1;16(13):3463-8. Epub 2006 May 2.

PMID:
16647257
14.

Enantiomerically pure 1,4-benzodiazepine-2,5-diones as Hdm2 antagonists.

Marugan JJ, Leonard K, Raboisson P, Gushue JM, Calvo R, Koblish HK, Lattanze J, Zhao S, Cummings MD, Player MR, Schubert C, Maroney AC, Lu T.

Bioorg Med Chem Lett. 2006 Jun 15;16(12):3115-20. Epub 2006 Apr 21.

PMID:
16630722
15.

Enhanced pharmacokinetic properties of 1,4-benzodiazepine-2,5-dione antagonists of the HDM2-p53 protein-protein interaction through structure-based drug design.

Parks DJ, LaFrance LV, Calvo RR, Milkiewicz KL, Marugán JJ, Raboisson P, Schubert C, Koblish HK, Zhao S, Franks CF, Lattanze J, Carver TE, Cummings MD, Maguire D, Grasberger BL, Maroney AC, Lu T.

Bioorg Med Chem Lett. 2006 Jun 15;16(12):3310-4. Epub 2006 Apr 4.

PMID:
16600594
16.

Benzodiazepinedione inhibitors of the Hdm2:p53 complex suppress human tumor cell proliferation in vitro and sensitize tumors to doxorubicin in vivo.

Koblish HK, Zhao S, Franks CF, Donatelli RR, Tominovich RM, LaFrance LV, Leonard KA, Gushue JM, Parks DJ, Calvo RR, Milkiewicz KL, Marugán JJ, Raboisson P, Cummings MD, Grasberger BL, Johnson DL, Lu T, Molloy CJ, Maroney AC.

Mol Cancer Ther. 2006 Jan;5(1):160-9.

17.

Structure-based design, synthesis, and biological evaluation of novel 1,4-diazepines as HDM2 antagonists.

Raboisson P, Marugán JJ, Schubert C, Koblish HK, Lu T, Zhao S, Player MR, Maroney AC, Reed RL, Huebert ND, Lattanze J, Parks DJ, Cummings MD.

Bioorg Med Chem Lett. 2005 Apr 1;15(7):1857-61.

PMID:
15780621
18.

Discovery and cocrystal structure of benzodiazepinedione HDM2 antagonists that activate p53 in cells.

Grasberger BL, Lu T, Schubert C, Parks DJ, Carver TE, Koblish HK, Cummings MD, LaFrance LV, Milkiewicz KL, Calvo RR, Maguire D, Lattanze J, Franks CF, Zhao S, Ramachandren K, Bylebyl GR, Zhang M, Manthey CL, Petrella EC, Pantoliano MW, Deckman IC, Spurlino JC, Maroney AC, Tomczuk BE, Molloy CJ, Bone RF.

J Med Chem. 2005 Feb 24;48(4):909-12.

PMID:
15715460

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