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Items: 1 to 20 of 48

1.

DNA modifications that do not cause gene mutations confer the potential for mutagenicity by combined treatment with food chemicals.

Ishii Y, Yokoo Y, Kijima A, Takasu S, Ogawa K, Umemura T.

Food Chem Toxicol. 2019 Jul;129:144-152. doi: 10.1016/j.fct.2019.04.011. Epub 2019 Apr 25.

PMID:
31029721
2.

Effects of inhibition of hepatic sulfotransferase activity on renal genotoxicity induced by lucidin-3-O-primeveroside.

Ishii Y, Kijima A, Takasu S, Ogawa K, Umemura T.

J Appl Toxicol. 2019 Apr;39(4):650-657. doi: 10.1002/jat.3755. Epub 2018 Dec 12.

PMID:
30874336
3.

Molecular Pathological Differences in Global Gene Expression between Two Sustained Proliferative Lesions, Nodular Regenerative Hepatocellular Hyperplasia and Hepatocellular Adenoma, in Mice.

Takasu S, Yokoo Y, Ishii Y, Kijima A, Ogawa K, Umemura T.

Toxicol Pathol. 2019 Jan;47(1):44-52. doi: 10.1177/0192623318810200. Epub 2018 Dec 20.

PMID:
30572783
4.

Mechanisms of oxidative stress-induced in vivo mutagenicity by potassium bromate and nitrofurantoin.

Tsuchiya T, Kijima A, Ishii Y, Takasu S, Yokoo Y, Nishikawa A, Yanai T, Umemura T.

J Toxicol Pathol. 2018 Jul;31(3):179-188. doi: 10.1293/tox.2018-0024. Epub 2018 Jun 2.

5.

Role of oxidative stress in the chemical structure-related genotoxicity of nitrofurantoin in Nrf2-deficient gpt delta mice.

Tsuchiya T, Kijima A, Ishii Y, Takasu S, Yokoo Y, Nishikawa A, Yanai T, Umemura T.

J Toxicol Pathol. 2018 Jul;31(3):169-178. doi: 10.1293/tox.2018-0014. Epub 2018 Jun 2.

6.

Mechanisms Underlying Exacerbation of Osmotic Nephrosis Caused by Pre-existing Kidney Injury.

Matsushita K, Takasu S, Kuroda K, Ishii Y, Kijima A, Ogawa K, Umemura T.

Toxicol Sci. 2018 Oct 1;165(2):420-430. doi: 10.1093/toxsci/kfy151.

PMID:
29947792
7.

Methods for the analysis of organophosphorus flame retardants-Comparison of GC-EI-MS, GC-NCI-MS, LC-ESI-MS/MS, and LC-APCI-MS/MS.

Tokumura M, Miyake Y, Wang Q, Nakayama H, Amagai T, Ogo S, Kume K, Kobayashi T, Takasu S, Ogawa K.

J Environ Sci Health A Tox Hazard Subst Environ Eng. 2018 Apr 16;53(5):475-481. doi: 10.1080/10934529.2017.1410419. Epub 2018 Jan 5.

PMID:
29303426
8.

Phosphorylation of protein phosphatase 2A facilitated an early stage of chemical carcinogenesis.

Ishii Y, Kuroda K, Matsushita K, Yokoo Y, Takasu S, Kijima A, Nohmi T, Ogawa K, Umemura T.

Toxicol Appl Pharmacol. 2017 Dec 1;336:75-83. doi: 10.1016/j.taap.2017.10.009. Epub 2017 Oct 17.

PMID:
29054680
9.

Simultaneous determination of brominated and phosphate flame retardants in flame-retarded polyester curtains by a novel extraction method.

Miyake Y, Tokumura M, Nakayama H, Wang Q, Amagai T, Ogo S, Kume K, Kobayashi T, Takasu S, Ogawa K, Kannan K.

Sci Total Environ. 2017 Dec 1;601-602:1333-1339. doi: 10.1016/j.scitotenv.2017.05.249. Epub 2017 Jun 9.

PMID:
28605852
10.

Osteopontin Deficiency Suppresses Intestinal Tumor Development in Apc-Deficient Min Mice.

Ishigamori R, Komiya M, Takasu S, Mutoh M, Imai T, Takahashi M.

Int J Mol Sci. 2017 May 14;18(5). pii: E1058. doi: 10.3390/ijms18051058.

11.

In vivo reporter gene mutation and micronucleus assays in gpt delta mice treated with a flame retardant decabromodiphenyl ether.

Takasu S, Ishii Y, Yokoo Y, Tsuchiya T, Kijima A, Kodama Y, Ogawa K, Umemura T.

Mutat Res Genet Toxicol Environ Mutagen. 2017 Apr;816-817:7-11. doi: 10.1016/j.mrgentox.2017.02.003. Epub 2017 Feb 22.

PMID:
28464995
12.

Effects of Nrf2 silencing on oxidative stress-associated intestinal carcinogenesis in mice.

Yokoo Y, Kijima A, Ishii Y, Takasu S, Tsuchiya T, Umemura T.

Cancer Med. 2016 Jun;5(6):1228-38. doi: 10.1002/cam4.672. Epub 2016 Feb 21.

13.

Anti-Inflammatory Effects of Capsaicin and Piperine on Helicobacter pylori-Induced Chronic Gastritis in Mongolian Gerbils.

Toyoda T, Shi L, Takasu S, Cho YM, Kiriyama Y, Nishikawa A, Ogawa K, Tatematsu M, Tsukamoto T.

Helicobacter. 2016 Apr;21(2):131-42. doi: 10.1111/hel.12243. Epub 2015 Jul 3.

PMID:
26140520
14.

Chemical structure-related mechanisms underlying in vivo genotoxicity induced by nitrofurantoin and its constituent moieties in gpt delta rats.

Kijima A, Ishii Y, Takasu S, Matsushita K, Kuroda K, Hibi D, Suzuki Y, Nohmi T, Umemura T.

Toxicology. 2015 May 4;331:125-35. doi: 10.1016/j.tox.2015.03.003. Epub 2015 Mar 12.

PMID:
25772432
15.

Role of p53 in the progression from ochratoxin A-induced DNA damage to gene mutations in the kidneys of mice.

Kuroda K, Hibi D, Ishii Y, Yokoo Y, Takasu S, Kijima A, Matsushita K, Masumura K, Kodama Y, Yanai T, Sakai H, Nohmi T, Ogawa K, Umemura T.

Toxicol Sci. 2015 Mar;144(1):65-76. doi: 10.1093/toxsci/kfu267. Epub 2015 Jan 29.

PMID:
25636497
16.

A medium-term gpt delta rat model as an in vivo system for analysis of renal carcinogenesis and the underlying mode of action.

Matsushita K, Ishii Y, Takasu S, Kuroda K, Kijima A, Tsuchiya T, Kawaguchi H, Miyoshi N, Nohmi T, Ogawa K, Nishikawa A, Umemura T.

Exp Toxicol Pathol. 2015 Jan;67(1):31-9. doi: 10.1016/j.etp.2014.09.006. Epub 2014 Oct 16.

PMID:
25446801
17.

Acrylamide induces specific DNA adduct formation and gene mutations in a carcinogenic target site, the mouse lung.

Ishii Y, Matsushita K, Kuroda K, Yokoo Y, Kijima A, Takasu S, Kodama Y, Nishikawa A, Umemura T.

Mutagenesis. 2015 Mar;30(2):227-35. doi: 10.1093/mutage/geu062. Epub 2014 Nov 12.

PMID:
25392148
18.

No effect of high fat diet-induced obesity on spontaneous reporter gene mutations in gpt delta mice.

Takasu S, Ishii Y, Matsushita K, Kuroda K, Kijima A, Kodama Y, Ogawa K, Umemura T.

Asian Pac J Cancer Prev. 2014;15(17):7149-52.

19.

Improvement and validation of a medium-term gpt delta rat model for predicting chemical carcinogenicity and underlying mode of action.

Matsushita K, Kuroda K, Ishii Y, Takasu S, Kijima A, Kawaguchi H, Miyoshi N, Nohmi T, Ogawa K, Nishikawa A, Umemura T.

Exp Toxicol Pathol. 2014 Sep;66(7):313-21. doi: 10.1016/j.etp.2014.05.002. Epub 2014 Jun 11.

PMID:
24929978
20.

In vivo genotoxicity of Ginkgo biloba extract in gpt delta mice and constitutive androstane receptor knockout mice.

Maeda J, Kijima A, Inoue K, Ishii Y, Ichimura R, Takasu S, Kuroda K, Matsushita K, Kodama Y, Saito N, Umemura T, Yoshida M.

Toxicol Sci. 2014 Aug 1;140(2):298-306. doi: 10.1093/toxsci/kfu090. Epub 2014 May 13.

PMID:
24824808

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