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Items: 18


In Vivo Imaging of Small Molecular Weight Peptides for Targeted Renal Drug Delivery: A Study in Normal and Polycystic Kidney Diseased Mice.

Lenhard S, McAlexander A, Virtue A, Fieles W, Skedzielewski T, Rambo M, Trinh H, Cheng SH, Hong H, Isidro-Llobet A, Nadin A, Geske R, Klein JL, Lee D, Jucker BM, Hu E.

J Pharmacol Exp Ther. 2019 Apr 1. pii: jpet.119.257022. doi: 10.1124/jpet.119.257022. [Epub ahead of print]


Microwave-Synthesized Platinum-Embedded Mesoporous Silica Nanoparticles as Dual-Modality Contrast Agents: Computed Tomography and Optical Imaging.

Chu CH, Cheng SH, Chen NT, Liao WN, Lo LW.

Int J Mol Sci. 2019 Mar 28;20(7). pii: E1560. doi: 10.3390/ijms20071560.


Development of a PET radioligand for potassium channels to image CNS demyelination.

Brugarolas P, Sánchez-Rodríguez JE, Tsai HM, Basuli F, Cheng SH, Zhang X, Caprariello AV, Lacroix JJ, Freifelder R, Murali D, DeJesus O, Miller RH, Swenson RE, Chen CT, Herscovitch P, Reich DS, Bezanilla F, Popko B.

Sci Rep. 2018 Jan 12;8(1):607. doi: 10.1038/s41598-017-18747-3.


Sensitivity evaluation and selective plane imaging geometry for x-ray-induced luminescence imaging.

Quigley BP, Smith CD, Cheng SH, Souris JS, Pelizzari CA, Chen CT, Lo LW, Reft CS, Wiersma RD, La Riviere PJ.

Med Phys. 2017 Oct;44(10):5367-5377. doi: 10.1002/mp.12470. Epub 2017 Sep 4.


Lectin-functionalized mesoporous silica nanoparticles for endoscopic detection of premalignant colonic lesions.

Chen NT, Souris JS, Cheng SH, Chu CH, Wang YC, Konda V, Dougherty U, Bissonnette M, Mou CY, Chen CT, Lo LW.

Nanomedicine. 2017 Aug;13(6):1941-1952. doi: 10.1016/j.nano.2017.03.014. Epub 2017 Mar 29.


Dynamic In Vivo SPECT Imaging of Neural Stem Cells Functionalized with Radiolabeled Nanoparticles for Tracking of Glioblastoma.

Cheng SH, Yu D, Tsai HM, Morshed RA, Kanojia D, Lo LW, Leoni L, Govind Y, Zhang L, Aboody KS, Lesniak MS, Chen CT, Balyasnikova IV.

J Nucl Med. 2016 Feb;57(2):279-84. doi: 10.2967/jnumed.115.163006. Epub 2015 Nov 12.


Radioluminescence characterization of in situ x-ray nanodosimeters: Potential real-time monitors and modulators of external beam radiation therapy.

Souris JS, Cheng SH, Pelizzari C, Chen NT, La Riviere P, Chen CT, Lo LW.

Appl Phys Lett. 2014 Nov 17;105(20):203110. Epub 2014 Nov 20.


Enhanced plasmonic resonance energy transfer in mesoporous silica-encased gold nanorod for two-photon-activated photodynamic therapy.

Chen NT, Tang KC, Chung MF, Cheng SH, Huang CM, Chu CH, Chou PT, Souris JS, Chen CT, Mou CY, Lo LW.

Theranostics. 2014 May 30;4(8):798-807. doi: 10.7150/thno.8934. eCollection 2014.


Nanoparticle-programmed self-destructive neural stem cells for glioblastoma targeting and therapy.

Cheng Y, Morshed R, Cheng SH, Tobias A, Auffinger B, Wainwright DA, Zhang L, Yunis C, Han Y, Chen CT, Lo LW, Aboody KS, Ahmed AU, Lesniak MS.

Small. 2013 Dec 20;9(24):4123-9. doi: 10.1002/smll.201301111. Epub 2013 Jul 21.


Recent advances in nanoparticle-based Förster resonance energy transfer for biosensing, molecular imaging and drug release profiling.

Chen NT, Cheng SH, Liu CP, Souris JS, Chen CT, Mou CY, Lo LW.

Int J Mol Sci. 2012 Dec 5;13(12):16598-623. doi: 10.3390/ijms131216598. Review.


Probing the dynamics of doxorubicin-DNA intercalation during the initial activation of apoptosis by fluorescence lifetime imaging microscopy (FLIM).

Chen NT, Wu CY, Chung CY, Hwu Y, Cheng SH, Mou CY, Lo LW.

PLoS One. 2012;7(9):e44947. doi: 10.1371/journal.pone.0044947. Epub 2012 Sep 18. Erratum in: PLoS One. 2012;7(11). doi:10.1371/annotation/4c43c8c8-0a4e-425b-a72f-74e84f6f3c28.


Visualizing dynamics of sub-hepatic distribution of nanoparticles using intravital multiphoton fluorescence microscopy.

Cheng SH, Li FC, Souris JS, Yang CS, Tseng FG, Lee HS, Chen CT, Dong CY, Lo LW.

ACS Nano. 2012 May 22;6(5):4122-31. doi: 10.1021/nn300558p. Epub 2012 Apr 19.


Mesoporous silica nanoparticles for the improved anticancer efficacy of cis-platin.

Lin CH, Cheng SH, Liao WN, Wei PR, Sung PJ, Weng CF, Lee CH.

Int J Pharm. 2012 Jun 15;429(1-2):138-47. doi: 10.1016/j.ijpharm.2012.03.026. Epub 2012 Mar 23.


Inorganic nanoparticles for enhanced photodynamic cancer therapy.

Cheng SH, Lo LW.

Curr Drug Discov Technol. 2011 Sep;8(3):250-68. Review.


Enhanced chemotherapy of cancer using pH-sensitive mesoporous silica nanoparticles to antagonize P-glycoprotein-mediated drug resistance.

Huang IP, Sun SP, Cheng SH, Lee CH, Wu CY, Yang CS, Lo LW, Lai YK.

Mol Cancer Ther. 2011 May;10(5):761-9. doi: 10.1158/1535-7163.MCT-10-0884. Epub 2011 Mar 16.


Intracellular pH-responsive mesoporous silica nanoparticles for the controlled release of anticancer chemotherapeutics.

Lee CH, Cheng SH, Huang IP, Souris JS, Yang CS, Mou CY, Lo LW.

Angew Chem Int Ed Engl. 2010 Oct 25;49(44):8214-9. doi: 10.1002/anie.201002639. No abstract available.


Surface charge-mediated rapid hepatobiliary excretion of mesoporous silica nanoparticles.

Souris JS, Lee CH, Cheng SH, Chen CT, Yang CS, Ho JA, Mou CY, Lo LW.

Biomaterials. 2010 Jul;31(21):5564-74. doi: 10.1016/j.biomaterials.2010.03.048. Epub 2010 Apr 24.


Enhanced photoacoustic stability of gold nanorods by silica matrix confinement.

Chen LC, Wei CW, Souris JS, Cheng SH, Chen CT, Yang CS, Li PC, Lo LW.

J Biomed Opt. 2010 Jan-Feb;15(1):016010. doi: 10.1117/1.3292574.


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