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Items: 1 to 20 of 22


Combination Therapy of Chloroquine and C₂-Ceramide Enhances Cytotoxicity in Lung Cancer H460 and H1299 Cells.

Chou HL, Lin YH, Liu W, Wu CY, Li RN, Huang HW, Chou CH, Chiou SJ, Chiu CC.

Cancers (Basel). 2019 Mar 15;11(3). pii: E370. doi: 10.3390/cancers11030370.


Thioridazine Enhances P62-Mediated Autophagy and Apoptosis Through Wnt/β-Catenin Signaling Pathway in Glioma Cells.

Chu CW, Ko HJ, Chou CH, Cheng TS, Cheng HW, Liang YH, Lai YL, Lin CY, Wang C, Loh JK, Cheng JT, Chiou SJ, Su CL, Huang CF, Hong YR.

Int J Mol Sci. 2019 Jan 22;20(3). pii: E473. doi: 10.3390/ijms20030473.


GSK3β‑mediated Ser156 phosphorylation modulates a BH3‑like domain in BCL2L12 during TMZ‑induced apoptosis and autophagy in glioma cells.

Chu CW, Yang MC, Chou CH, Huang WS, Hsiao BX, Wang YT, Chiou SJ, Loh JK, Hong YR.

Int J Mol Med. 2018 Aug;42(2):905-918. doi: 10.3892/ijmm.2018.3672. Epub 2018 May 11.


The origin of GSKIP, a multifaceted regulatory factor in the mammalian Wnt pathway.

Chou CH, Yang MC, Hsiao BX, Wang YH, Liu HF, Chiou SJ, Chuang YC, Yang CN, Lieu AS, Loh JK, Howng SL, Chou AK, Tseng CN, Cheng JT, Hong YR.

Biochim Biophys Acta Mol Cell Res. 2018 Aug;1865(8):1046-1059. doi: 10.1016/j.bbamcr.2018.04.008. Epub 2018 Apr 23.


A molecular dynamics simulation study decodes the Zika virus NS5 methyltransferase bound to SAH and RNA analogue.

Chuang CH, Chiou SJ, Cheng TL, Wang YT.

Sci Rep. 2018 Apr 20;8(1):6336. doi: 10.1038/s41598-018-24775-4.


Hexane fraction of Pluchea indica root extract inhibits proliferation and induces autophagy in human glioblastoma cells.

Cho CL, Lee YZ, Tseng CN, Cho J, Cheng YB, Wang KW, Chen HJ, Chiou SJ, Chou CH, Hong YR.

Biomed Rep. 2017 Nov;7(5):416-422. doi: 10.3892/br.2017.979. Epub 2017 Sep 11.


A 4-Phenoxyphenol Derivative Exerts Inhibitory Effects on Human Hepatocellular Carcinoma Cells through Regulating Autophagy and Apoptosis Accompanied by Downregulating α-Tubulin Expression.

Chang WT, Liu W, Chiu YH, Chen BH, Chuang SC, Chen YC, Hsu YT, Lu MJ, Chiou SJ, Chou CK, Chiu CC.

Molecules. 2017 May 21;22(5). pii: E854. doi: 10.3390/molecules22050854.


A novel role for β2-microglobulin: a precursor of antibacterial chemokine in respiratory epithelial cells.

Chiou SJ, Wang CC, Tseng YS, Lee YJ, Chen SC, Chou CH, Chuang LY, Hong YR, Lu CY, Chiu CC, Chignard M.

Sci Rep. 2016 Aug 9;6:31035. doi: 10.1038/srep31035.


Arecoline-induced pro-fibrotic proteins in LLC-PK1 cells are dependent on c-Jun N-terminal kinase.

Lin SH, Chiou SJ, Ho WT, Chuang CT, Chuang LY, Guh JY.

Toxicology. 2016 Feb 17;344-346:53-60. doi: 10.1016/j.tox.2016.02.004. Epub 2016 Feb 22.


Decipher β2-microglobulin: gain- or loss-of-function (a mini-review).

Chiou SJ, Chen CH.

Med Sci Monit Basic Res. 2013 Oct 21;19:271-3. doi: 10.12659/MSMBR.889457. Review.


Ubiquitin C-terminal hydrolase-L5 is required for high glucose-induced transforming growth factor-β receptor I expression and hypertrophy in mesangial cells.

Ko YM, Chang CY, Chiou SJ, Hsu FJ, Huang JS, Yang YL, Guh JY, Chuang LY.

Arch Biochem Biophys. 2013 Jul 15;535(2):177-86. doi: 10.1016/ Epub 2013 Mar 13.


Gefitinib attenuates transforming growth factor-β1-activated mitogen-activated protein kinases and mitogenesis in NRK-49F cells.

Chen SC, Guh JY, Lin TD, Chiou SJ, Hwang CC, Ko YM, Chuang LY.

Transl Res. 2011 Oct;158(4):214-24. doi: 10.1016/j.trsl.2011.06.002. Epub 2011 Jul 7.


Lymphocyte α-kinase is a gout-susceptible gene involved in monosodium urate monohydrate-induced inflammatory responses.

Wang SJ, Tu HP, Ko AM, Chiang SL, Chiou SJ, Lee SS, Tsai YS, Lee CP, Ko YC.

J Mol Med (Berl). 2011 Dec;89(12):1241-51. doi: 10.1007/s00109-011-0796-5. Epub 2011 Aug 7.


Vascular hyperpermeability in response to inflammatory mustard oil is mediated by Rho kinase in mice systemically exposed to arsenic.

Chen SC, Liu CC, Huang SY, Chiou SJ.

Microvasc Res. 2011 Sep;82(2):182-9. doi: 10.1016/j.mvr.2011.06.001. Epub 2011 Jun 16.


Involvement of the residues of GSKIP, AxinGID, and FRATtide in their binding with GSK3beta to unravel a novel C-terminal scaffold-binding region.

Howng SL, Hwang CC, Hsu CY, Hsu MY, Teng CY, Chou CH, Lee MF, Wu CH, Chiou SJ, Lieu AS, Loh JK, Yang CN, Lin CS, Hong YR.

Mol Cell Biochem. 2010 Jun;339(1-2):23-33. doi: 10.1007/s11010-009-0366-0. Epub 2009 Dec 31.


Advanced glycation end-products activate extracellular signal-regulated kinase via the oxidative stress-EGF receptor pathway in renal fibroblasts.

Chen SC, Guh JY, Hwang CC, Chiou SJ, Lin TD, Ko YM, Huang JS, Yang YL, Chuang LY.

J Cell Biochem. 2010 Jan 1;109(1):38-48. doi: 10.1002/jcb.22376.


Characterization of membranous and cytoplasmic EGFR expression in human normal renal cortex and renal cell carcinoma.

Pu YS, Huang CY, Kuo YZ, Kang WY, Liu GY, Huang AM, Yu HJ, Lai MK, Huang SP, Wu WJ, Chiou SJ, Hour TC.

J Biomed Sci. 2009 Sep 12;16:82. doi: 10.1186/1423-0127-16-82.


Interactions across the interface contribute the stability of homodimeric 3alpha-hydroxysteroid dehydrogenase/carbonyl reductase.

Hwang CC, Hsu CN, Huang TJ, Chiou SJ, Hong YR.

Arch Biochem Biophys. 2009 Oct 1;490(1):36-41. doi: 10.1016/ Epub 2009 Aug 14.


Arecoline-induced phosphorylated p53 and p21(WAF1) protein expression is dependent on ATM/ATR and phosphatidylinositol-3-kinase in clone-9 cells.

Chou WW, Guh JY, Tsai JF, Hwang CC, Chiou SJ, Chuang LY.

J Cell Biochem. 2009 Jun 1;107(3):408-17. doi: 10.1002/jcb.22137.


Advanced glycation end-product-inhibited cell proliferation and protein expression of beta-catenin and cyclin D1 are dependent on glycogen synthase kinase 3beta in LLC-PK1 cells.

Lin KH, Guh JY, Mo JF, Chiou SJ, Hwang CC, Chuang LY.

Arch Biochem Biophys. 2008 Sep 1;477(1):27-32. doi: 10.1016/ Epub 2008 Apr 29.


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