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Items: 1 to 20 of 56

1.

On the prevention of kidney uptake of radiolabeled DARPins.

Altai M, Garousi J, Rinne SS, Schulga A, Deyev S, Vorobyeva A.

EJNMMI Res. 2020 Feb 4;10(1):7. doi: 10.1186/s13550-020-0599-1.

PMID:
32020413
2.

Laser-Ablative Synthesis of Isotope-Enriched Samarium Oxide Nanoparticles for Nuclear Nanomedicine.

Popova-Kuznetsova E, Tikhonowski G, Popov AA, Duflot V, Deyev S, Klimentov S, Zavestovskaya I, Prasad PN, Kabashin AV.

Nanomaterials (Basel). 2019 Dec 28;10(1). pii: E69. doi: 10.3390/nano10010069.

3.

Effect of a radiolabel biochemical nature on tumor-targeting properties of EpCAM-binding engineered scaffold protein DARPin Ec1.

Deyev SM, Vorobyeva A, Schulga A, Abouzayed A, Günther T, Garousi J, Konovalova E, Ding H, Gräslund T, Orlova A, Tolmachev V.

Int J Biol Macromol. 2020 Feb 15;145:216-225. doi: 10.1016/j.ijbiomac.2019.12.147. Epub 2019 Dec 19.

4.

New Frontiers in Diagnosis and Therapy of Circulating Tumor Markers in Cerebrospinal Fluid In Vitro and In Vivo.

Sindeeva OA, Verkhovskii RA, Sarimollaoglu M, Afanaseva GA, Fedonnikov AS, Osintsev EY, Kurochkina EN, Gorin DA, Deyev SM, Zharov VP, Galanzha EI.

Cells. 2019 Oct 2;8(10). pii: E1195. doi: 10.3390/cells8101195. Review.

5.

DARPin_9-29-Targeted Mini Gold Nanorods Specifically Eliminate HER2-Overexpressing Cancer Cells.

Proshkina G, Deyev S, Ryabova A, Tavanti F, Menziani MC, Cohen R, Katrivas L, Kotlyar A.

ACS Appl Mater Interfaces. 2019 Sep 25;11(38):34645-34651. doi: 10.1021/acsami.9b10441. Epub 2019 Sep 10.

PMID:
31448887
6.

Optimal composition and position of histidine-containing tags improves biodistribution of 99mTc-labeled DARPin G3.

Vorobyeva A, Schulga A, Konovalova E, Güler R, Löfblom J, Sandström M, Garousi J, Chernov V, Bragina O, Orlova A, Tolmachev V, Deyev SM.

Sci Rep. 2019 Jun 28;9(1):9405. doi: 10.1038/s41598-019-45795-8.

7.

Indirect Radioiodination of DARPin G3 Using N-succinimidyl-Para-Iodobenzoate Improves the Contrast of HER2 Molecular Imaging.

Vorobyeva A, Schulga A, Rinne SS, Günther T, Orlova A, Deyev S, Tolmachev V.

Int J Mol Sci. 2019 Jun 21;20(12). pii: E3047. doi: 10.3390/ijms20123047.

8.

HER2-Specific Targeted Toxin DARPin-LoPE: Immunogenicity and Antitumor Effect on Intraperitoneal Ovarian Cancer Xenograft Model.

Sokolova EA, Shilova ON, Kiseleva DV, Schulga AA, Balalaeva IV, Deyev SM.

Int J Mol Sci. 2019 May 15;20(10). pii: E2399. doi: 10.3390/ijms20102399.

9.

Penetration Efficiency of Antitumor Agents in Ovarian Cancer Spheroids: The Case of Recombinant Targeted Toxin DARPin-LoPE and the Chemotherapy Drug, Doxorubicin.

Sokolova E, Kutova O, Grishina A, Pospelov A, Guryev E, Schulga A, Deyev S, Balalaeva I.

Pharmaceutics. 2019 May 7;11(5). pii: E219. doi: 10.3390/pharmaceutics11050219.

10.

Preclinical Study of Biofunctional Polymer-Coated Upconversion Nanoparticles.

Guryev EL, Shilyagina NY, Kostyuk AB, Sencha LM, Balalaeva IV, Vodeneev VA, Kutova OM, Lyubeshkin AV, Yakubovskaya RI, Pankratov AA, Ingel FI, Novik TS, Deyev SM, Ermilov SA, Zvyagin AV.

Toxicol Sci. 2019 Jul 1;170(1):123-132. doi: 10.1093/toxsci/kfz086.

PMID:
30985900
11.

Comparison of tumor‑targeting properties of directly and indirectly radioiodinated designed ankyrin repeat protein (DARPin) G3 variants for molecular imaging of HER2.

Vorobyeva A, Sсhulga A, Konovalova E, Güler R, Mitran B, Garousi J, Rinne S, Löfblom J, Orlova A, Deyev S, Tolmachev V.

Int J Oncol. 2019 Apr;54(4):1209-1220. doi: 10.3892/ijo.2019.4712. Epub 2019 Feb 11.

12.

Comparative Evaluation of Two DARPin Variants: Effect of Affinity, Size, and Label on Tumor Targeting Properties.

Deyev S, Vorobyeva A, Schulga A, Proshkina G, Güler R, Löfblom J, Mitran B, Garousi J, Altai M, Buijs J, Chernov V, Orlova A, Tolmachev V.

Mol Pharm. 2019 Mar 4;16(3):995-1008. doi: 10.1021/acs.molpharmaceut.8b00922. Epub 2019 Feb 8.

PMID:
30608701
13.

Data on characterization of magnetic nanoparticles stabilized with fusion protein of Barstar and C-term part of Mms6.

Shipunova VO, Kotelnikova PA, Aghayeva UF, Stremovskiy OA, Schulga AA, Nikitin MP, Deyev SM.

Data Brief. 2018 Nov 3;21:1659-1663. doi: 10.1016/j.dib.2018.10.173. eCollection 2018 Dec.

14.

3D in vitro models of tumors expressing EGFR family receptors: a potent tool for studying receptor biology and targeted drug development.

Sokolova EA, Vodeneev VA, Deyev SM, Balalaeva IV.

Drug Discov Today. 2019 Jan;24(1):99-111. doi: 10.1016/j.drudis.2018.09.003. Epub 2018 Sep 8. Review.

PMID:
30205170
15.

Radioactive (90Y) upconversion nanoparticles conjugated with recombinant targeted toxin for synergistic nanotheranostics of cancer.

Guryev EL, Volodina NO, Shilyagina NY, Gudkov SV, Balalaeva IV, Volovetskiy AB, Lyubeshkin AV, Sen' AV, Ermilov SA, Vodeneev VA, Petrov RV, Zvyagin AV, Alferov ZI, Deyev SM.

Proc Natl Acad Sci U S A. 2018 Sep 25;115(39):9690-9695. doi: 10.1073/pnas.1809258115. Epub 2018 Sep 7.

16.

Neuroblastoma Origin and Therapeutic Targets for Immunotherapy.

Kholodenko IV, Kalinovsky DV, Doronin II, Deyev SM, Kholodenko RV.

J Immunol Res. 2018 Jul 11;2018:7394268. doi: 10.1155/2018/7394268. eCollection 2018. Review.

17.

Disassembling a cancer puzzle: Cell junctions and plasma membrane as targets for anticancer therapy.

Shilova ON, Shilov ES, Lieber A, Deyev SM.

J Control Release. 2018 Sep 28;286:125-136. doi: 10.1016/j.jconrel.2018.07.030. Epub 2018 Jul 17. Review.

PMID:
30030181
18.

Comparative Evaluation of Radioiodine and Technetium-Labeled DARPin 9_29 for Radionuclide Molecular Imaging of HER2 Expression in Malignant Tumors.

Vorobyeva A, Bragina O, Altai M, Mitran B, Orlova A, Shulga A, Proshkina G, Chernov V, Tolmachev V, Deyev S.

Contrast Media Mol Imaging. 2018 Jun 6;2018:6930425. doi: 10.1155/2018/6930425. eCollection 2018.

19.

Selective staining and eradication of cancer cells by protein-carrying DARPin-functionalized liposomes.

Deyev S, Proshkina G, Baryshnikova O, Ryabova A, Avishai G, Katrivas L, Giannini C, Levi-Kalisman Y, Kotlyar A.

Eur J Pharm Biopharm. 2018 Sep;130:296-305. doi: 10.1016/j.ejpb.2018.06.026. Epub 2018 Jun 26.

20.

Versatile Platform for Nanoparticle Surface Bioengineering Based on SiO2-Binding Peptide and Proteinaceous Barnase*Barstar Interface.

Shipunova VO, Zelepukin IV, Stremovskiy OA, Nikitin MP, Care A, Sunna A, Zvyagin AV, Deyev SM.

ACS Appl Mater Interfaces. 2018 May 23;10(20):17437-17447. doi: 10.1021/acsami.8b01627. Epub 2018 May 9.

PMID:
29701945

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