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Items: 1 to 20 of 23


Long pentraxin PTX3 mediates acute inflammatory responses against pneumococcal infection.

Koh SH, Shin SG, Andrade MJ, Go RH, Park S, Woo CH, Lim JH.

Biochem Biophys Res Commun. 2017 Nov 4;493(1):671-676. doi: 10.1016/j.bbrc.2017.08.133. Epub 2017 Aug 31.


Simulating Intestinal Transporter and Enzyme Activity in a Physiologically Based Pharmacokinetic Model for Tenofovir Disoproxil Fumarate.

Moss DM, Domanico P, Watkins M, Park S, Randolph R, Wring S, Rajoli RKR, Hobson J, Rannard S, Siccardi M, Owen A.

Antimicrob Agents Chemother. 2017 Jun 27;61(7). pii: e00105-17. doi: 10.1128/AAC.00105-17. Print 2017 Jul.


Preclinical Pharmacokinetics and Pharmacodynamic Target of SCY-078, a First-in-Class Orally Active Antifungal Glucan Synthesis Inhibitor, in Murine Models of Disseminated Candidiasis.

Wring SA, Randolph R, Park S, Abruzzo G, Chen Q, Flattery A, Garrett G, Peel M, Outcalt R, Powell K, Trucksis M, Angulo D, Borroto-Esoda K.

Antimicrob Agents Chemother. 2017 Mar 24;61(4). pii: e02068-16. doi: 10.1128/AAC.02068-16. Print 2017 Apr.


Development of a Novel Formulation That Improves Preclinical Bioavailability of Tenofovir Disoproxil Fumarate.

Watkins ME, Wring S, Randolph R, Park S, Powell K, Lutz L, Nowakowski M, Ramabhadran R, Domanico PL.

J Pharm Sci. 2017 Mar;106(3):906-919. doi: 10.1016/j.xphs.2016.12.003. Epub 2016 Dec 14.


The TRPCs, Orais and STIMs in ER/PM Junctions.

Shin DM, Son A, Park S, Kim MS, Ahuja M, Muallem S.

Adv Exp Med Biol. 2016;898:47-66. doi: 10.1007/978-3-319-26974-0_3. Review.


Role of protein kinase A and class II phosphatidylinositol 3-kinase C2β in the downregulation of KCa3.1 channel synthesis and membrane surface expression by lyso-globotriaosylceramide.

Choi JY, Park S.

Biochem Biophys Res Commun. 2016 Feb 19;470(4):907-12. doi: 10.1016/j.bbrc.2016.01.152. Epub 2016 Jan 26.


Orai1 and STIM1 in ER/PM junctions: roles in pancreatic cell function and dysfunction.

Son A, Park S, Shin DM, Muallem S.

Am J Physiol Cell Physiol. 2016 Mar 15;310(6):C414-22. doi: 10.1152/ajpcell.00349.2015. Epub 2016 Jan 6. Review.


Lyso-globotriaosylceramide downregulates KCa3.1 channel expression to inhibit collagen synthesis in fibroblasts.

Choi JY, Shin MY, Suh SH, Park S.

Biochem Biophys Res Commun. 2015 Dec 25;468(4):883-8. doi: 10.1016/j.bbrc.2015.11.050. Epub 2015 Nov 22.


The ER/PM microdomain, PI(4,5)P₂ and the regulation of STIM1-Orai1 channel function.

Cao X, Choi S, Maléth JJ, Park S, Ahuja M, Muallem S.

Cell Calcium. 2015 Oct;58(4):342-8. doi: 10.1016/j.ceca.2015.03.003. Epub 2015 Mar 18. Review.


cAMP and Ca²⁺ signaling in secretory epithelia: crosstalk and synergism.

Ahuja M, Jha A, Maléth J, Park S, Muallem S.

Cell Calcium. 2014 Jun;55(6):385-93. doi: 10.1016/j.ceca.2014.01.006. Epub 2014 Feb 7. Review.


Mechanism and synergism in epithelial fluid and electrolyte secretion.

Hong JH, Park S, Shcheynikov N, Muallem S.

Pflugers Arch. 2014 Aug;466(8):1487-99. doi: 10.1007/s00424-013-1390-1. Epub 2013 Nov 16. Review.


Globotriaosylceramide induces lysosomal degradation of endothelial KCa3.1 in fabry disease.

Choi S, Kim JA, Na HY, Cho SE, Park S, Jung SC, Suh SH.

Arterioscler Thromb Vasc Biol. 2014 Jan;34(1):81-9. doi: 10.1161/ATVBAHA.113.302200. Epub 2013 Oct 24.


Irbit mediates synergy between ca(2+) and cAMP signaling pathways during epithelial transport in mice.

Park S, Shcheynikov N, Hong JH, Zheng C, Suh SH, Kawaai K, Ando H, Mizutani A, Abe T, Kiyonari H, Seki G, Yule D, Mikoshiba K, Muallem S.

Gastroenterology. 2013 Jul;145(1):232-241. doi: 10.1053/j.gastro.2013.03.047. Epub 2013 Mar 28.


NADPH oxidase 2-derived superoxide downregulates endothelial KCa3.1 in preeclampsia.

Choi S, Kim JA, Na HY, Kim JE, Park S, Han KH, Kim YJ, Suh SH.

Free Radic Biol Med. 2013 Apr;57:10-21. doi: 10.1016/j.freeradbiomed.2012.12.009. Epub 2012 Dec 20.


The WNK/SPAK and IRBIT/PP1 pathways in epithelial fluid and electrolyte transport.

Park S, Hong JH, Ohana E, Muallem S.

Physiology (Bethesda). 2012 Oct;27(5):291-9. doi: 10.1152/physiol.00028.2012. Review.


Modafinil inhibits K(Ca)3.1 currents and muscle contraction via a cAMP-dependent mechanism.

Choi S, Kim MY, Joo KY, Park S, Kim JA, Jung JC, Oh S, Suh SH.

Pharmacol Res. 2012 Jul;66(1):51-9. doi: 10.1016/j.phrs.2012.02.009. Epub 2012 Mar 5.


Globotriaosylceramide leads to K(Ca)3.1 channel dysfunction: a new insight into endothelial dysfunction in Fabry disease.

Park S, Kim JA, Joo KY, Choi S, Choi EN, Shin JA, Han KH, Jung SC, Suh SH.

Cardiovasc Res. 2011 Feb 1;89(2):290-9. doi: 10.1093/cvr/cvq333. Epub 2010 Oct 21.


In vitro metabolism, permeability, and efflux of bazedoxifene in humans.

Shen L, Ahmad S, Park S, DeMaio W, Oganesian A, Hultin T, Scatina J, Bungay P, Chandrasekaran A.

Drug Metab Dispos. 2010 Sep;38(9):1471-9. doi: 10.1124/dmd.109.030999. Epub 2010 Jun 1.


Modulation of nonselective cation current by oxidized LDL and lysophosphatidylcholine and its inhibitory contribution to endothelial damage.

Liang GH, Park S, Kim MY, Kim JA, Choi S, Suh SH.

Life Sci. 2010 May 8;86(19-20):733-9. doi: 10.1016/j.lfs.2010.03.005. Epub 2010 Mar 11.


Superoxide generated by lysophosphatidylcholine induces endothelial nitric oxide synthase downregulation in human endothelial cells.

Choi S, Park S, Liang GH, Kim JA, Suh SH.

Cell Physiol Biochem. 2010;25(2-3):233-40. doi: 10.1159/000276557. Epub 2010 Jan 12.

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