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Items: 8


The Plasma Factor XIII Heterotetrameric Complex Structure: Unexpected Unequal Pairing within a Symmetric Complex.

Singh S, Nazabal A, Kaniyappan S, Pellequer JL, Wolberg AS, Imhof D, Oldenburg J, Biswas A.

Biomolecules. 2019 Nov 21;9(12). pii: E765. doi: 10.3390/biom9120765.


Disruption of Structural Disulfides of Coagulation FXIII-B Subunit; Functional Implications for a Rare Bleeding Disorder.

Singh S, Akhter MS, Dodt J, Sharma A, Kaniyappan S, Yadegari H, Ivaskevicius V, Oldenburg J, Biswas A.

Int J Mol Sci. 2019 Apr 22;20(8). pii: E1956. doi: 10.3390/ijms20081956.


Suppressing Tau Aggregation and Toxicity by an Anti-Aggregant Tau Fragment.

Pir GJ, Choudhary B, Kaniyappan S, Chandupatla RR, Mandelkow E, Mandelkow EM, Wang Y.

Mol Neurobiol. 2019 May;56(5):3751-3767. doi: 10.1007/s12035-018-1326-z. Epub 2018 Sep 8.


Pathological missorting of endogenous MAPT/Tau in neurons caused by failure of protein degradation systems.

Balaji V, Kaniyappan S, Mandelkow E, Wang Y, Mandelkow EM.

Autophagy. 2018;14(12):2139-2154. doi: 10.1080/15548627.2018.1509607. Epub 2018 Sep 13.


Purification and Characterization of Low-n Tau Oligomers.

Kaniyappan S, Chandupatla RR, Mandelkow E.

Methods Mol Biol. 2018;1779:99-111. doi: 10.1007/978-1-4939-7816-8_8.


Extracellular low-n oligomers of tau cause selective synaptotoxicity without affecting cell viability.

Kaniyappan S, Chandupatla RR, Mandelkow EM, Mandelkow E.

Alzheimers Dement. 2017 Nov;13(11):1270-1291. doi: 10.1016/j.jalz.2017.04.002. Epub 2017 May 18.


The release and trans-synaptic transmission of Tau via exosomes.

Wang Y, Balaji V, Kaniyappan S, Krüger L, Irsen S, Tepper K, Chandupatla R, Maetzler W, Schneider A, Mandelkow E, Mandelkow EM.

Mol Neurodegener. 2017 Jan 13;12(1):5. doi: 10.1186/s13024-016-0143-y.


Stages and conformations of the Tau repeat domain during aggregation and its effect on neuronal toxicity.

Kumar S, Tepper K, Kaniyappan S, Biernat J, Wegmann S, Mandelkow EM, Müller DJ, Mandelkow E.

J Biol Chem. 2014 Jul 18;289(29):20318-32. doi: 10.1074/jbc.M114.554725. Epub 2014 May 13.

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