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Items: 18


Post-Exposure Protection in Mice against Sudan Virus by a Two Antibody Cocktail.

Froude JW, Herbert AS, Pelat T, Miethe S, Zak SE, Brannan JM, Bakken RR, Steiner AR, Yin G, Hallam TJ, Sato AK, Hust M, Thullier P, Dye JM.

Viruses. 2018 May 26;10(6). pii: E286. doi: 10.3390/v10060286.


Human-Like Neutralizing Antibodies Protect Mice from Aerosol Exposure with Western Equine Encephalitis Virus.

Burke CW, Froude JW, Miethe S, Hülseweh B, Hust M, Glass PJ.

Viruses. 2018 Mar 24;10(4). pii: E147. doi: 10.3390/v10040147.


Construction of Macaque Immune-Libraries.

Avril A, Miethe S, Hust M, Pelat T.

Methods Mol Biol. 2018;1701:83-112. doi: 10.1007/978-1-4939-7447-4_5.


The European AntibotABE Framework Program and Its Update: Development of Innovative Botulinum Antibodies.

Rasetti-Escargueil C, Avril A, Miethe S, Mazuet C, Derman Y, Selby K, Thullier P, Pelat T, Urbain R, Fontayne A, Korkeala H, Sesardic D, Hust M, Popoff MR.

Toxins (Basel). 2017 Oct 2;9(10). pii: E309. doi: 10.3390/toxins9100309. Review.


Generation and characterization of protective antibodies to Marburg virus.

Froude JW, Pelat T, Miethe S, Zak SE, Wec AZ, Chandran K, Brannan JM, Bakken RR, Hust M, Thullier P, Dye JM.

MAbs. 2017 May/Jun;9(4):696-703. doi: 10.1080/19420862.2017.1299848. Epub 2017 Mar 13.


Neutralization of Botulinum Neurotoxin Type E by a Humanized Antibody.

Derman Y, Selby K, Miethe S, Frenzel A, Liu Y, Rasetti-Escargueil C, Avril A, Pelat T, Urbain R, Fontayne A, Thullier P, Sesardic D, Lindström M, Hust M, Korkeala H.

Toxins (Basel). 2016 Sep 12;8(9). pii: E257. doi: 10.3390/toxins8090257.


Development of Germline-Humanized Antibodies Neutralizing Botulinum Neurotoxin A and B.

Miethe S, Mazuet C, Liu Y, Tierney R, Rasetti-Escargueil C, Avril A, Frenzel A, Thullier P, Pelat T, Urbain R, Fontayne A, Sesardic D, Hust M, Popoff MR.

PLoS One. 2016 Aug 25;11(8):e0161446. doi: 10.1371/journal.pone.0161446. eCollection 2016.


Generation of Recombinant Antibodies Against Toxins and Viruses by Phage Display for Diagnostics and Therapy.

Unkauf T, Miethe S, Fühner V, Schirrmann T, Frenzel A, Hust M.

Adv Exp Med Biol. 2016;917:55-76. doi: 10.1007/978-3-319-32805-8_4. Review.


Recombinant antibodies for diagnostics and therapy against pathogens and toxins generated by phage display.

Kuhn P, Fühner V, Unkauf T, Moreira GM, Frenzel A, Miethe S, Hust M.

Proteomics Clin Appl. 2016 Oct;10(9-10):922-948. doi: 10.1002/prca.201600002. Epub 2016 Jun 21. Review.


A transplant "immunome" screening platform defines a targetable epitope fingerprint of multiple myeloma.

Schieferdecker A, Oberle A, Thiele B, Hofmann F, Göthel M, Miethe S, Hust M, Braig F, Voigt M, von Pein UM, Koch-Nolte F, Haag F, Alawi M, Indenbirken D, Grundhoff A, Bokemeyer C, Bacher U, Kröger N, Binder M.

Blood. 2016 Jun 23;127(25):3202-14. doi: 10.1182/blood-2015-10-676536. Epub 2016 Mar 31.


Development of Human-Like scFv-Fc Neutralizing Botulinum Neurotoxin E.

Miethe S, Rasetti-Escargueil C, Avril A, Liu Y, Chahboun S, Korkeala H, Mazuet C, Popoff MR, Pelat T, Thullier P, Sesardic D, Hust M.

PLoS One. 2015 Oct 6;10(10):e0139905. doi: 10.1371/journal.pone.0139905. eCollection 2015.


Isolation of nanomolar scFvs of non-human primate origin, cross-neutralizing botulinum neurotoxins A1 and A2 by targeting their heavy chain.

Avril A, Miethe S, Popoff MR, Mazuet C, Chahboun S, Rasetti-Escargueil C, Sesardic D, Thullier P, Hust M, Pelat T.

BMC Biotechnol. 2015 Sep 17;15:86. doi: 10.1186/s12896-015-0206-0.


Development of human-like scFv-Fc antibodies neutralizing Botulinum toxin serotype B.

Rasetti-Escargueil C, Avril A, Chahboun S, Tierney R, Bak N, Miethe S, Mazuet C, Popoff MR, Thullier P, Hust M, Pelat T, Sesardic D.

MAbs. 2015;7(6):1161-77. doi: 10.1080/19420862.2015.1082016. Epub 2015 Sep 18.


Development of neutralizing scFv-Fc against botulinum neurotoxin A light chain from a macaque immune library.

Miethe S, Rasetti-Escargueil C, Liu Y, Chahboun S, Pelat T, Avril A, Frenzel A, Schirrmann T, Thullier P, Sesardic D, Hust M.

MAbs. 2014 Mar-Apr;6(2):446-59. doi: 10.4161/mabs.27773. Epub 2014 Jan 9.


Production of single chain fragment variable (scFv) antibodies in Escherichia coli using the LEX™ bioreactor.

Miethe S, Meyer T, Wöhl-Bruhn S, Frenzel A, Schirrmann T, Dübel S, Hust M.

J Biotechnol. 2013 Jan 20;163(2):105-11. doi: 10.1016/j.jbiotec.2012.07.011. Epub 2012 Aug 9.


Encapsulation of proteins in hydrogel carrier systems for controlled drug delivery: influence of network structure and drug size on release rate.

Bertz A, Wöhl-Bruhn S, Miethe S, Tiersch B, Koetz J, Hust M, Bunjes H, Menzel H.

J Biotechnol. 2013 Jan 20;163(2):243-9. doi: 10.1016/j.jbiotec.2012.06.036. Epub 2012 Jul 10.


Identification of immunogenic proteins and generation of antibodies against Salmonella Typhimurium using phage display.

Meyer T, Schirrmann T, Frenzel A, Miethe S, Stratmann-Selke J, Gerlach GF, Strutzberg-Minder K, Dübel S, Hust M.

BMC Biotechnol. 2012 Jun 15;12:29. doi: 10.1186/1472-6750-12-29.


Isolation of a nanomolar scFv inhibiting the endopeptidase activity of botulinum toxin A, by single-round panning of an immune phage-displayed library of macaque origin.

Chahboun S, Hust M, Liu Y, Pelat T, Miethe S, Helmsing S, Jones RG, Sesardic D, Thullier P.

BMC Biotechnol. 2011 Nov 23;11:113. doi: 10.1186/1472-6750-11-113.

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