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Items: 1 to 20 of 54

1.

Intramuscular administration of hexachloroplatinate reverses cyanide-induced metabolic derangements and counteracts severe cyanide poisoning.

Morningstar J, Lee J, Hendry-Hofer T, Witeof A, Lyle LT, Knipp G, MacRae CA, Boss GR, Peterson RT, Davisson VJ, Gerszten RE, Bebarta VS, Mahon S, Brenner M, Nath AK.

FASEB Bioadv. 2019 Feb;1(2):81-92. doi: 10.1096/fba.1024. Epub 2018 Oct 8.

PMID:
31355359
2.

Determination of free cyano-cobinamide in swine and rabbit plasma by liquid chromatography tandem mass spectrometry.

Dzisam JK, Brenner M, Mahon SB, Rockwood GA, Logue BA.

J Chromatogr B Analyt Technol Biomed Life Sci. 2019 Aug 15;1124:100-108. doi: 10.1016/j.jchromb.2019.05.020. Epub 2019 May 28.

PMID:
31185415
3.

Efficacy of Oral Administration of Sodium Thiosulfate and Glycine in a Large, Swine Model of Oral Cyanide Toxicity.

Ng PC, Hendry-Hofer TB, Witeof AE, Mahon SB, Brenner M, Boss GR, Bebarta VS.

Ann Emerg Med. 2019 May 9. pii: S0196-0644(19)30242-2. doi: 10.1016/j.annemergmed.2019.03.023. [Epub ahead of print]

PMID:
31080026
4.

Hydrogen Sulfide Toxicity: Mechanism of Action, Clinical Presentation, and Countermeasure Development.

Ng PC, Hendry-Hofer TB, Witeof AE, Brenner M, Mahon SB, Boss GR, Haouzi P, Bebarta VS.

J Med Toxicol. 2019 May 6. doi: 10.1007/s13181-019-00710-5. [Epub ahead of print] Review.

PMID:
31062177
5.

Intramuscular sodium tetrathionate as an antidote in a clinically relevant swine model of acute cyanide toxicity.

Hendry-Hofer TB, Witeof AE, Ng PC, Mahon SB, Brenner M, Boss GR, Bebarta VS.

Clin Toxicol (Phila). 2019 Apr 22:1-7. doi: 10.1080/15563650.2019.1602272. [Epub ahead of print]

PMID:
31008657
6.

Metabolism of Cyanide by Glutathione To Produce the Novel Cyanide Metabolite 2-Aminothiazoline-4-oxoaminoethanoic Acid.

Gyamfi OA, Bortey-Sam N, Mahon SB, Brenner M, Rockwood GA, Logue BA.

Chem Res Toxicol. 2019 Apr 15;32(4):718-726. doi: 10.1021/acs.chemrestox.8b00384. Epub 2019 Feb 21.

PMID:
30724077
7.

Correction to: Monitoring Dose Response of Cyanide Antidote Dimethyl Trisulfide in Rabbits Using Diffuse Optical Spectroscopy.

Lee J, Rockwood G, Logue B, Manandhar E, Petrikovics I, Han C, Bebarta V, Mahon SB, Burney T, Brenner M.

J Med Toxicol. 2019 Apr;15(2):139. doi: 10.1007/s13181-018-0694-0.

8.

A Review on Ingested Cyanide: Risks, Clinical Presentation, Diagnostics, and Treatment Challenges.

Hendry-Hofer TB, Ng PC, Witeof AE, Mahon SB, Brenner M, Boss GR, Bebarta VS.

J Med Toxicol. 2019 Apr;15(2):128-133. doi: 10.1007/s13181-018-0688-y. Epub 2018 Dec 11. Review.

PMID:
30539383
9.

Intramuscular cobinamide versus saline for treatment of severe hydrogen sulfide toxicity in swine.

Ng PC, Hendry-Hofer TB, Garrett N, Brenner M, Mahon SB, Maddry JK, Haouzi P, Boss GR, Gibbons TF, AraƱa AA, Bebarta VS.

Clin Toxicol (Phila). 2019 Mar;57(3):189-196. doi: 10.1080/15563650.2018.1504955. Epub 2018 Nov 15.

10.

Intramuscular dimethyl trisulfide: efficacy in a large swine model of acute severe cyanide toxicity.

Hendry-Hofer TB, Witeof AE, Lippner DS, Ng PC, Mahon SB, Brenner M, Rockwood GA, Bebarta VS.

Clin Toxicol (Phila). 2019 Apr;57(4):265-270. doi: 10.1080/15563650.2018.1511800. Epub 2018 Oct 11.

PMID:
30306816
11.

Characterization of a Swine (Sus scrofa) Model of Oral Potassium Cyanide Intoxication.

Ng PC, Hendry-Hofer TB, Witeof AE, Brenner M, Mahon SB, Boss GR, Bebarta VS.

Comp Med. 2018 Oct 1;68(5):375-379. doi: 10.30802/AALAS-CM-18-000041. Epub 2018 Sep 12.

12.

Monitoring Dose Response of Cyanide Antidote Dimethyl Trisulfide in Rabbits Using Diffuse Optical Spectroscopy.

Lee J, Rockwood G, Logue B, Manandhar E, Petrikovics I, Han C, Bebarta V, Mahon SB, Burney T, Brenner M.

J Med Toxicol. 2018 Dec;14(4):295-305. doi: 10.1007/s13181-018-0680-6. Epub 2018 Aug 9. Erratum in: J Med Toxicol. 2019 Jan 3;:.

PMID:
30094773
13.

Automated 3D segmentation of methyl isocyanate-exposed rat trachea using an ultra-thin, fully fiber optic optical coherence endoscopic probe.

Miao Y, Jing JC, Desai V, Mahon SB, Brenner M, Veress LA, White CW, Chen Z.

Sci Rep. 2018 Jun 7;8(1):8713. doi: 10.1038/s41598-018-26389-2.

14.

Identification of specific metabolic pathways as druggable targets regulating the sensitivity to cyanide poisoning.

Sips PY, Shi X, Musso G, Nath AK, Zhao Y, Nielson J, Morningstar J, Kelly AE, Mikell B, Buys E, Bebarta V, Rutter J, Davisson VJ, Mahon S, Brenner M, Boss GR, Peterson RT, Gerszten RE, MacRae CA.

PLoS One. 2018 Jun 7;13(6):e0193889. doi: 10.1371/journal.pone.0193889. eCollection 2018.

15.

Faraday Waves-Based Integrated Ultrasonic Micro-Droplet Generator and Applications.

Tsai CS, Mao RW, Tsai SC, Shahverdi K, Zhu Y, Lin SK, Hsu YH, Boss G, Brenner M, Mahon S, Smaldone GC.

Micromachines (Basel). 2017;8(2). pii: 56. doi: 10.3390/mi8020056. Epub 2017 Feb 14.

16.

Oral Glycine and Sodium Thiosulfate for Lethal Cyanide Ingestion.

Brenner M, Azer SM, Oh KJ, Han CH, Lee J, Mahon SB, Du X, Mukai D, Burney T, Saidian M, Chan A, Straker DI, Bebarta VS, Boss GR.

J Clin Toxicol. 2017 Jun;7(3). pii: 355. doi: 10.4172/2167-7972.1000355. Epub 2017 Jun 27.

17.

Efficacy of Intravenous Cobinamide Versus Hydroxocobalamin or Saline for Treatment of Severe Hydrogen Sulfide Toxicity in a Swine (Sus scrofa) Model.

Bebarta VS, Garrett N, Brenner M, Mahon SB, Maddry JK, Boudreau S, Castaneda M, Boss GR.

Acad Emerg Med. 2017 Sep;24(9):1088-1098. doi: 10.1111/acem.13213. Epub 2017 Aug 9.

18.

Cisplatin Analogs Confer Protection against Cyanide Poisoning.

Nath AK, Shi X, Harrison DL, Morningstar JE, Mahon S, Chan A, Sips P, Lee J, MacRae CA, Boss GR, Brenner M, Gerszten RE, Peterson RT.

Cell Chem Biol. 2017 May 18;24(5):565-575.e4. doi: 10.1016/j.chembiol.2017.03.013. Epub 2017 Apr 13.

19.

Sodium Nitrite and Sodium Thiosulfate Are Effective Against Acute Cyanide Poisoning When Administered by Intramuscular Injection.

Bebarta VS, Brittain M, Chan A, Garrett N, Yoon D, Burney T, Mukai D, Babin M, Pilz RB, Mahon SB, Brenner M, Boss GR.

Ann Emerg Med. 2017 Jun;69(6):718-725.e4. doi: 10.1016/j.annemergmed.2016.09.034. Epub 2016 Dec 29.

20.

A countermeasure development pipeline.

MacRae CA, Boss G, Brenner M, Gerszten RE, Mahon S, Peterson RT.

Ann N Y Acad Sci. 2016 Aug;1378(1):58-67. doi: 10.1111/nyas.13224. Review.

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