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Items: 13

1.

DNA silencing by prokaryotic Argonaute proteins adds a new layer of defense against invading nucleic acids.

Willkomm S, Makarova KS, Grohmann D.

FEMS Microbiol Rev. 2018 May 1;42(3):376-387. doi: 10.1093/femsre/fuy010. Review.

2.

Site-Specific Labelling of Native Mammalian Proteins for Single-Molecule FRET Measurements.

Gust A, Jakob L, Zeitler DM, Bruckmann A, Kramm K, Willkomm S, Tinnefeld P, Meister G, Grohmann D.

Chembiochem. 2018 Apr 16;19(8):780-783. doi: 10.1002/cbic.201700696. Epub 2018 Mar 6.

PMID:
29394002
3.

Structural and mechanistic insights into an archaeal DNA-guided Argonaute protein.

Willkomm S, Oellig CA, Zander A, Restle T, Keegan R, Grohmann D, Schneider S.

Nat Microbiol. 2017 Mar 20;2:17035. doi: 10.1038/nmicrobiol.2017.35.

PMID:
28319084
4.

Guide-independent DNA cleavage by archaeal Argonaute from Methanocaldococcus jannaschii.

Zander A, Willkomm S, Ofer S, van Wolferen M, Egert L, Buchmeier S, Stöckl S, Tinnefeld P, Schneider S, Klingl A, Albers SV, Werner F, Grohmann D.

Nat Microbiol. 2017 Mar 20;2:17034. doi: 10.1038/nmicrobiol.2017.34.

PMID:
28319081
5.

Site-Specific Fluorescent Labeling of Argonaute for FRET-Based Bio-Assays.

Willkomm S, Zander A, Grohmann D.

Methods Mol Biol. 2017;1517:291-304.

PMID:
27924490
6.

Kinetic Analysis of Target RNA Binding and Slicing by Human Argonaute 2 Protein.

Willkomm S, Restle T.

Methods Mol Biol. 2017;1517:277-290.

PMID:
27924489
7.

Mechanistic Insights into Archaeal and Human Argonaute Substrate Binding and Cleavage Properties.

Willkomm S, Zander A, Grohmann D, Restle T.

PLoS One. 2016 Oct 14;11(10):e0164695. doi: 10.1371/journal.pone.0164695. eCollection 2016.

8.

Recombinant hTRBP and hPACT Modulate hAgo2-Catalyzed siRNA-Mediated Target RNA Cleavage In Vitro.

Willkomm S, Deerberg A, Heidemann J, Flügge F, Meine J, Hu R, Kretschmer-Kazemi Far R, Restle T.

PLoS One. 2016 Jan 19;11(1):e0146814. doi: 10.1371/journal.pone.0146814. eCollection 2016.

9.

Novel Insights into Guide RNA 5'-Nucleoside/Tide Binding by Human Argonaute 2.

Kalia M, Willkomm S, Claussen JC, Restle T, Bonvin AM.

Int J Mol Sci. 2015 Dec 24;17(1). pii: E22. doi: 10.3390/ijms17010022.

10.

RNAi revised--target mRNA-dependent enhancement of gene silencing.

Dornseifer S, Willkomm S, Far RK, Liebschwager J, Beltsiou F, Frank K, Laufer SD, Martinetz T, Sczakiel G, Claussen JC, Restle T.

Nucleic Acids Res. 2015 Dec 15;43(22):10623-32. doi: 10.1093/nar/gkv1200. Epub 2015 Nov 17.

11.

Conformational Dynamics of Ago-Mediated Silencing Processes.

Willkomm S, Restle T.

Int J Mol Sci. 2015 Jul 1;16(7):14769-85. doi: 10.3390/ijms160714769. Review.

12.

A prokaryotic twist on argonaute function.

Willkomm S, Zander A, Gust A, Grohmann D.

Life (Basel). 2015 Feb 16;5(1):538-53. doi: 10.3390/life5010538. Review.

13.

Minimal mechanistic model of siRNA-dependent target RNA slicing by recombinant human Argonaute 2 protein.

Deerberg A, Willkomm S, Restle T.

Proc Natl Acad Sci U S A. 2013 Oct 29;110(44):17850-5. doi: 10.1073/pnas.1217838110. Epub 2013 Oct 7.

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