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Items: 1 to 20 of 109

1.

Regulation of host-microbe interactions at oral mucosal barriers by type 17 immunity.

Gaffen SL, Moutsopoulos NM.

Sci Immunol. 2020 Jan 3;5(43). pii: eaau4594. doi: 10.1126/sciimmunol.aau4594. Review.

PMID:
31901072
2.

The IL-17R/IL-22R signaling axis is dispensable for vulvovaginal candidiasis regardless of estrogen status.

Peters BM, Coleman BM, Willems HME, Barker KS, Aggor FEY, Cipolla E, Verma AH, Bishu S, Huppler AH, Bruno VM, Gaffen SL.

J Infect Dis. 2019 Dec 5. pii: jiz649. doi: 10.1093/infdis/jiz649. [Epub ahead of print]

PMID:
31805183
3.

IL-17 receptor-based signaling and implications for disease.

Li X, Bechara R, Zhao J, McGeachy MJ, Gaffen SL.

Nat Immunol. 2019 Dec;20(12):1594-1602. doi: 10.1038/s41590-019-0514-y. Epub 2019 Nov 19. Review.

PMID:
31745337
4.

Interleukin-22 (IL-22) Binding Protein Constrains IL-22 Activity, Host Defense, and Oxidative Phosphorylation Genes during Pneumococcal Pneumonia.

Trevejo-Nunez G, Elsegeiny W, Aggor FEY, Tweedle JL, Kaplan Z, Gandhi P, Castillo P, Ferguson A, Alcorn JF, Chen K, Kolls JK, Gaffen SL.

Infect Immun. 2019 Oct 18;87(11). pii: e00550-19. doi: 10.1128/IAI.00550-19. Print 2019 Nov.

PMID:
31451621
5.

Empowering Women: Moving from Awareness to Action at the Immunology of Fungal Infections Gordon Research Conference.

Ballou ER, Gaffen SL, Gow NAR, Hise AG.

Pathogens. 2019 Jul 17;8(3). pii: E103. doi: 10.3390/pathogens8030103.

6.

Candidalysin: discovery and function in Candida albicans infections.

Naglik JR, Gaffen SL, Hube B.

Curr Opin Microbiol. 2019 Dec;52:100-109. doi: 10.1016/j.mib.2019.06.002. Epub 2019 Jul 6. Review.

7.

Candidalysin activates innate epithelial immune responses via epidermal growth factor receptor.

Ho J, Yang X, Nikou SA, Kichik N, Donkin A, Ponde NO, Richardson JP, Gratacap RL, Archambault LS, Zwirner CP, Murciano C, Henley-Smith R, Thavaraj S, Tynan CJ, Gaffen SL, Hube B, Wheeler RT, Moyes DL, Naglik JR.

Nat Commun. 2019 May 24;10(1):2297. doi: 10.1038/s41467-019-09915-2.

8.

Fungus Among Us: The Frenemies Within.

Aggor FEY, Way SS, Gaffen SL.

Trends Immunol. 2019 Jun;40(6):469-471. doi: 10.1016/j.it.2019.04.007. Epub 2019 Apr 30.

PMID:
31053496
9.

The IL-17 Family of Cytokines in Health and Disease.

McGeachy MJ, Cua DJ, Gaffen SL.

Immunity. 2019 Apr 16;50(4):892-906. doi: 10.1016/j.immuni.2019.03.021. Review.

PMID:
30995505
10.

IL-17 metabolically reprograms activated fibroblastic reticular cells for proliferation and survival.

Majumder S, Amatya N, Revu S, Jawale CV, Wu D, Rittenhouse N, Menk A, Kupul S, Du F, Raphael I, Bhattacharjee A, Siebenlist U, Hand TW, Delgoffe GM, Poholek AC, Gaffen SL, Biswas PS, McGeachy MJ.

Nat Immunol. 2019 May;20(5):534-545. doi: 10.1038/s41590-019-0367-4. Epub 2019 Apr 8.

11.

Dermatophyte Immune Memory Is Only Skin-Deep.

Verma AH, Gaffen SL.

J Invest Dermatol. 2019 Mar;139(3):517-519. doi: 10.1016/j.jid.2018.10.022.

PMID:
30797318
12.

Combined Blockade of TNF-α and IL-17A Alleviates Progression of Collagen-Induced Arthritis without Causing Serious Infections in Mice.

Shen F, Verma AH, Volk A, Jones B, Coleman BM, Loza MJ, Malaviya R, Moore B, Weinstock D, Elloso MM, Gaffen SL, Ort T.

J Immunol. 2019 Apr 1;202(7):2017-2026. doi: 10.4049/jimmunol.1801436. Epub 2019 Feb 11.

PMID:
30745461
13.

IL-17 integrates multiple self-reinforcing, feed-forward mechanisms through the RNA binding protein Arid5a.

Amatya N, Childs EE, Cruz JA, Aggor FEY, Garg AV, Berman AJ, Gudjonsson JE, Atasoy U, Gaffen SL.

Sci Signal. 2018 Oct 9;11(551). pii: eaat4617. doi: 10.1126/scisignal.aat4617.

14.

T Cell Receptor-Independent, CD31/IL-17A-Driven Inflammatory Axis Shapes Synovitis in Juvenile Idiopathic Arthritis.

Ferguson ID, Griffin P, Michel JJ, Yano H, Gaffen SL, Mueller RG, Dvergsten JA, Piganelli JD, Rosenkranz ME, Kietz DA, Vallejo AN.

Front Immunol. 2018 Aug 6;9:1802. doi: 10.3389/fimmu.2018.01802. eCollection 2018.

15.

IL-36 and IL-1/IL-17 Drive Immunity to Oral Candidiasis via Parallel Mechanisms.

Verma AH, Zafar H, Ponde NO, Hepworth OW, Sihra D, Aggor FEY, Ainscough JS, Ho J, Richardson JP, Coleman BM, Hube B, Stacey M, McGeachy MJ, Naglik JR, Gaffen SL, Moyes DL.

J Immunol. 2018 Jul 15;201(2):627-634. doi: 10.4049/jimmunol.1800515. Epub 2018 Jun 11.

16.

Innate Immunity to Mucosal Candida Infections.

Verma A, Gaffen SL, Swidergall M.

J Fungi (Basel). 2017 Oct 31;3(4). pii: E60. doi: 10.3390/jof3040060. Review.

17.

Processing of Candida albicans Ece1p Is Critical for Candidalysin Maturation and Fungal Virulence.

Richardson JP, Mogavero S, Moyes DL, Blagojevic M, Krüger T, Verma AH, Coleman BM, De La Cruz Diaz J, Schulz D, Ponde NO, Carrano G, Kniemeyer O, Wilson D, Bader O, Enoiu SI, Ho J, Kichik N, Gaffen SL, Hube B, Naglik JR.

mBio. 2018 Jan 23;9(1). pii: e02178-17. doi: 10.1128/mBio.02178-17.

18.

Candida albicans-epithelial interactions and induction of mucosal innate immunity.

Naglik JR, König A, Hube B, Gaffen SL.

Curr Opin Microbiol. 2017 Dec;40:104-112. doi: 10.1016/j.mib.2017.10.030. Epub 2017 Nov 17. Review.

19.

IL-22 neutralizing autoantibodies impair fungal clearance in murine oropharyngeal candidiasis model.

Bichele R, Kärner J, Truusalu K, Smidt I, Mändar R, Conti HR, Gaffen SL, Peterson P, Laan M, Kisand K.

Eur J Immunol. 2018 Mar;48(3):464-470. doi: 10.1002/eji.201747209. Epub 2017 Dec 11.

20.

Oral epithelial cells orchestrate innate type 17 responses to Candida albicans through the virulence factor candidalysin.

Verma AH, Richardson JP, Zhou C, Coleman BM, Moyes DL, Ho J, Huppler AR, Ramani K, McGeachy MJ, Mufazalov IA, Waisman A, Kane LP, Biswas PS, Hube B, Naglik JR, Gaffen SL.

Sci Immunol. 2017 Nov 3;2(17). pii: eaam8834. doi: 10.1126/sciimmunol.aam8834.

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