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Items: 1 to 20 of 33

1.

Progress in the development of more effective and safer analgesics for pain management.

Turnaturi R, Chiechio S, Salerno L, Rescifina A, Pittalà V, Cantarella G, Tomarchio E, Parenti C, Pasquinucci L.

Eur J Med Chem. 2019 Dec 1;183:111701. doi: 10.1016/j.ejmech.2019.111701. Epub 2019 Sep 16. Review.

PMID:
31550662
2.

Preclinical evidence of enhanced analgesic activity of duloxetine complexed with succinyl-β-cyclodextrin: A comparative study with cyclodextrin complexes.

Seggio M, Contino A, Maccarrone G, Parenti C, Merlo S, Pappalardo G, Giuffrida A, Chiechio S.

Int J Pharm. 2019 Jul 20;566:391-399. doi: 10.1016/j.ijpharm.2019.05.077. Epub 2019 May 31.

PMID:
31158453
3.

Synthesis, in vitro and in vivo characterization of new benzoxazole and benzothiazole-based sigma receptor ligands.

Romeo G, Prezzavento O, Intagliata S, Pittalà V, Modica MN, Marrazzo A, Turnaturi R, Parenti C, Chiechio S, Arena E, Campisi A, Sposito G, Salerno L.

Eur J Med Chem. 2019 Jul 15;174:226-235. doi: 10.1016/j.ejmech.2019.04.056. Epub 2019 Apr 21.

PMID:
31042618
4.

Simultaneous Activation of Mu and Delta Opioid Receptors Reduces Allodynia and Astrocytic Connexin 43 in an Animal Model of Neuropathic Pain.

Vicario N, Pasquinucci L, Spitale FM, Chiechio S, Turnaturi R, Caraci F, Tibullo D, Avola R, Gulino R, Parenti R, Parenti C.

Mol Neurobiol. 2019 Nov;56(11):7338-7354. doi: 10.1007/s12035-019-1607-1. Epub 2019 Apr 28.

PMID:
31030416
5.

(2S)-N-2-methoxy-2-phenylethyl-6,7-benzomorphan compound (2S-LP2): Discovery of a biased mu/delta opioid receptor agonist.

Pasquinucci L, Turnaturi R, Calò G, Pappalardo F, Ferrari F, Russo G, Arena E, Montenegro L, Chiechio S, Prezzavento O, Parenti C.

Eur J Med Chem. 2019 Apr 15;168:189-198. doi: 10.1016/j.ejmech.2019.02.043. Epub 2019 Feb 18.

PMID:
30822708
6.

Simultaneous targeting of MOR/DOR: A useful strategy for inflammatory pain modulation.

Pasquinucci L, Turnaturi R, Montenegro L, Caraci F, Chiechio S, Parenti C.

Eur J Pharmacol. 2019 Mar 15;847:97-102. doi: 10.1016/j.ejphar.2019.01.031. Epub 2019 Jan 25.

PMID:
30690004
7.

l-Acetylcarnitine: A Mechanistically Distinctive and Potentially Rapid-Acting Antidepressant Drug.

Chiechio S, Canonico PL, Grilli M.

Int J Mol Sci. 2017 Dec 21;19(1). pii: E11. doi: 10.3390/ijms19010011. Review.

8.

Chronic Treatment with Fluoxetine Induces Sex-Dependent Analgesic Effects and Modulates HDAC2 and mGlu2 Expression in Female Mice.

Zammataro M, Merlo S, Barresi M, Parenti C, Hu H, Sortino MA, Chiechio S.

Front Pharmacol. 2017 Oct 20;8:743. doi: 10.3389/fphar.2017.00743. eCollection 2017.

9.

Rosemary Essential Oil-Loaded Lipid Nanoparticles: In Vivo Topical Activity from Gel Vehicles.

Montenegro L, Pasquinucci L, Zappalà A, Chiechio S, Turnaturi R, Parenti C.

Pharmaceutics. 2017 Oct 21;9(4). pii: E48. doi: 10.3390/pharmaceutics9040048.

10.

Repeated activation of delta opiod receptors counteracts nerve injury-induced TNF-α up-regulation in the sciatic nerve of rats with neuropathic pain: A possible correlation with delta opiod receptors-mediated antiallodinic effect.

Vicario N, Parenti R, Arico' G, Turnaturi R, Scoto GM, Chiechio S, Parenti C.

Mol Pain. 2016 Sep 2;12. pii: 1744806916667949. doi: 10.1177/1744806916667949. Print 2016. No abstract available.

11.

Modulation of Chronic Pain by Metabotropic Glutamate Receptors.

Chiechio S.

Adv Pharmacol. 2016;75:63-89. doi: 10.1016/bs.apha.2015.11.001. Epub 2016 Jan 6. Review.

PMID:
26920009
12.

Involvement of the Heme-Oxygenase Pathway in the Antiallodynic and Antihyperalgesic Activity of Harpagophytum procumbens in Rats.

Parenti C, Aricò G, Chiechio S, Di Benedetto G, Parenti R, Scoto GM.

Molecules. 2015 Sep 15;20(9):16758-69. doi: 10.3390/molecules200916758.

13.

Monomeric ß-amyloid interacts with type-1 insulin-like growth factor receptors to provide energy supply to neurons.

Giuffrida ML, Tomasello MF, Pandini G, Caraci F, Battaglia G, Busceti C, Di Pietro P, Pappalardo G, Attanasio F, Chiechio S, Bagnoli S, Nacmias B, Sorbi S, Vigneri R, Rizzarelli E, Nicoletti F, Copani A.

Front Cell Neurosci. 2015 Aug 7;9:297. doi: 10.3389/fncel.2015.00297. eCollection 2015.

14.

HDAC and HAT inhibitors differently affect analgesia mediated by group II metabotropic glutamate receptors.

Zammataro M, Sortino MA, Parenti C, Gereau RW 4th, Chiechio S.

Mol Pain. 2014 Nov 18;10:68. doi: 10.1186/1744-8069-10-68.

15.

Acetyl-L-carnitine: from a biological curiosity to a drug for the peripheral nervous system and beyond.

Onofrj M, Ciccocioppo F, Varanese S, di Muzio A, Calvani M, Chiechio S, Osio M, Thomas A.

Expert Rev Neurother. 2013 Aug;13(8):925-36. doi: 10.1586/14737175.2013.814930. Review.

PMID:
23965166
16.

Beta-amyloid monomer and insulin/IGF-1 signaling in Alzheimer's disease.

Giuffrida ML, Tomasello F, Caraci F, Chiechio S, Nicoletti F, Copani A.

Mol Neurobiol. 2012 Dec;46(3):605-13. doi: 10.1007/s12035-012-8313-6. Epub 2012 Aug 12. Review.

PMID:
22886436
17.

Curcumin loaded NLC induces histone hypoacetylation in the CNS after intraperitoneal administration in mice.

Puglia C, Frasca G, Musumeci T, Rizza L, Puglisi G, Bonina F, Chiechio S.

Eur J Pharm Biopharm. 2012 Jun;81(2):288-93. doi: 10.1016/j.ejpb.2012.03.015. Epub 2012 Apr 3.

PMID:
22504443
18.

Hyperalgesic activity of kisspeptin in mice.

Spampinato S, Trabucco A, Biasiotta A, Biagioni F, Cruccu G, Copani A, Colledge WH, Sortino MA, Nicoletti F, Chiechio S.

Mol Pain. 2011 Nov 23;7:90. doi: 10.1186/1744-8069-7-90.

19.

Metabotropic glutamate receptors and the control of chronic pain.

Chiechio S, Nicoletti F.

Curr Opin Pharmacol. 2012 Feb;12(1):28-34. doi: 10.1016/j.coph.2011.10.010. Epub 2011 Oct 29. Review.

PMID:
22040745
20.

Development, characterization, and in vitro and in vivo evaluation of benzocaine- and lidocaine-loaded nanostructrured lipid carriers.

Puglia C, Sarpietro MG, Bonina F, Castelli F, Zammataro M, Chiechio S.

J Pharm Sci. 2011 May;100(5):1892-9. doi: 10.1002/jps.22416. Epub 2010 Dec 10.

PMID:
21374621

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