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Items: 1 to 20 of 67

1.

Exploring the size of the lipophilic unit of the soluble epoxide hydrolase inhibitors.

Codony S, Valverde E, Leiva R, Brea J, Isabel Loza M, Morisseau C, Hammock BD, Vázquez S.

Bioorg Med Chem. 2019 Aug 26:115078. doi: 10.1016/j.bmc.2019.115078. [Epub ahead of print]

PMID:
31488357
2.

11β-HSD1 Inhibition Rescues SAMP8 Cognitive Impairment Induced by Metabolic Stress.

Puigoriol-Illamola D, Leiva R, Vázquez-Carrera M, Vázquez S, Griñán-Ferré C, Pallàs M.

Mol Neurobiol. 2019 Aug 9. doi: 10.1007/s12035-019-01708-4. [Epub ahead of print]

PMID:
31399953
3.

A novel class of multitarget anti-Alzheimer benzohomoadamantane‒chlorotacrine hybrids modulating cholinesterases and glutamate NMDA receptors.

Pérez-Areales FJ, Turcu AL, Barniol-Xicota M, Pont C, Pivetta D, Espargaró A, Bartolini M, De Simone A, Andrisano V, Pérez B, Sabate R, Sureda FX, Vázquez S, Muñoz-Torrero D.

Eur J Med Chem. 2019 Oct 15;180:613-626. doi: 10.1016/j.ejmech.2019.07.051. Epub 2019 Jul 17.

PMID:
31351393
4.

Stevens-Johnson syndrome and toxic epidermal necrolysis: a retrospective descriptive study.

Carrasquillo OY, Santiago-Vazquez M, Cardona R, Cruz-Manzano M, Figueroa LD.

Int J Dermatol. 2019 Jun 5. doi: 10.1111/ijd.14493. [Epub ahead of print]

PMID:
31166019
5.

Oral administration of a new HRI activator as a new strategy to improve high-fat-diet-induced glucose intolerance, hepatic steatosis, and hypertriglyceridaemia through FGF21.

Zarei M, Pujol E, Quesada-López T, Villarroya F, Barroso E, Vázquez S, Pizarro-Delgado J, Palomer X, Vázquez-Carrera M.

Br J Pharmacol. 2019 Jul;176(13):2292-2305. doi: 10.1111/bph.14678. Epub 2019 May 23.

PMID:
30927369
6.

Chronic spontaneous urticaria associated with colon adenocarcinoma: A paraneoplastic manifestation? A case report and review of literature.

Santiago-Vázquez M, Barrera-Llaurador J, Carrasquillo OY, Sánchez S.

JAAD Case Rep. 2018 Dec 15;5(1):101-103. doi: 10.1016/j.jdcr.2018.10.021. eCollection 2019 Jan. No abstract available.

7.

Pentafluorosulfanyl-containing Triclocarban Analogs with Potent Antimicrobial Activity.

Pujol E, Blanco-Cabra N, Julián E, Leiva R, Torrents E, Vázquez S.

Molecules. 2018 Nov 2;23(11). pii: E2853. doi: 10.3390/molecules23112853.

8.

Pigmented Lesions of the Nail Unit.

Nevares-Pomales OW, Sarriera-Lazaro CJ, Barrera-Llaurador J, Santiago-Vazquez M, Lugo-Fagundo N, Sanchez JE, Sanchez JL.

Am J Dermatopathol. 2018 Nov;40(11):793-804. doi: 10.1097/DAD.0000000000001106. Review.

PMID:
30339563
9.

Novel Quinazolinone Inhibitors of ALK2 Flip between Alternate Binding Modes: Structure-Activity Relationship, Structural Characterization, Kinase Profiling, and Cellular Proof of Concept.

Hudson L, Mui J, Vázquez S, Carvalho DM, Williams E, Jones C, Bullock AN, Hoelder S.

J Med Chem. 2018 Aug 23;61(16):7261-7272. doi: 10.1021/acs.jmedchem.8b00782. Epub 2018 Aug 7.

10.

Palladium-catalyzed cocyclotrimerization of arynes with a pyramidalized alkene.

Alonso JM, Quiroga S, Codony S, Turcu AL, Barniol-Xicota M, Pérez D, Guitián E, Vázquez S, Peña D.

Chem Commun (Camb). 2018 Jun 8;54(47):5996-5999. doi: 10.1039/c8cc03188f.

PMID:
29790509
11.

Pharmacological and Electrophysiological Characterization of Novel NMDA Receptor Antagonists.

Leiva R, Phillips MB, Turcu AL, Gratacòs-Batlle E, León-García L, Sureda FX, Soto D, Johnson JW, Vázquez S.

ACS Chem Neurosci. 2018 Nov 21;9(11):2722-2730. doi: 10.1021/acschemneuro.8b00154. Epub 2018 Jun 1.

PMID:
29767953
12.

11β-HSD1 Inhibition by RL-118 Promotes Autophagy and Correlates with Reduced Oxidative Stress and Inflammation, Enhancing Cognitive Performance in SAMP8 Mouse Model.

Puigoriol-Illamola D, Griñán-Ferré C, Vasilopoulou F, Leiva R, Vázquez S, Pallàs M.

Mol Neurobiol. 2018 Dec;55(12):8904-8915. doi: 10.1007/s12035-018-1026-8. Epub 2018 Apr 2.

PMID:
29611102
13.

Rare Variant of Agminated Spitz Nevi on a Hypopigmented Background and Segmental Distribution: Case Report and Review of Literature.

Nevares-Pomales OW, Carrasquillo OY, Santiago-Vazquez M, Colon-Fontanez F.

Am J Dermatopathol. 2018 Sep;40(9):686-689. doi: 10.1097/DAD.0000000000001135. Review.

PMID:
29533278
14.

Exploring N-acyl-4-azatetracyclo[5.3.2.02,6.08,10]dodec-11-enes as 11β-HSD1 Inhibitors.

Leiva R, McBride A, Binnie M, Webster SP, Vázquez S.

Molecules. 2018 Feb 28;23(3). pii: E536. doi: 10.3390/molecules23030536.

15.

Towards a Novel Class of Multitarget-Directed Ligands: Dual P2X7-NMDA Receptor Antagonists.

Karoutzou O, Kwak SH, Lee SD, Martínez-Falguera D, Sureda FX, Vázquez S, Kim YC, Barniol-Xicota M.

Molecules. 2018 Jan 21;23(1). pii: E230. doi: 10.3390/molecules23010230.

16.

Stratification during evaporative assembly of multicomponent nanoparticle films.

Liu X, Liu W, Carr AJ, Santiago Vazquez D, Nykypanchuk D, Majewski PW, Routh AF, Bhatia SR.

J Colloid Interface Sci. 2018 Apr 1;515:70-77. doi: 10.1016/j.jcis.2018.01.005. Epub 2018 Jan 3.

PMID:
29331782
17.

Hepatic regulation of VLDL receptor by PPARβ/δ and FGF21 modulates non-alcoholic fatty liver disease.

Zarei M, Barroso E, Palomer X, Dai J, Rada P, Quesada-López T, Escolà-Gil JC, Cedó L, Zali MR, Molaei M, Dabiri R, Vázquez S, Pujol E, Valverde ÁM, Villarroya F, Liu Y, Wahli W, Vázquez-Carrera M.

Mol Metab. 2018 Feb;8:117-131. doi: 10.1016/j.molmet.2017.12.008. Epub 2017 Dec 19.

18.

Aniline-Based Inhibitors of Influenza H1N1 Virus Acting on Hemagglutinin-Mediated Fusion.

Leiva R, Barniol-Xicota M, Codony S, Ginex T, Vanderlinden E, Montes M, Caffrey M, Luque FJ, Naesens L, Vázquez S.

J Med Chem. 2018 Jan 11;61(1):98-118. doi: 10.1021/acs.jmedchem.7b00908. Epub 2017 Dec 22.

PMID:
29220568
19.

Design, synthesis and in vivo study of novel pyrrolidine-based 11β-HSD1 inhibitors for age-related cognitive dysfunction.

Leiva R, Griñan-Ferré C, Seira C, Valverde E, McBride A, Binnie M, Pérez B, Luque FJ, Pallàs M, Bidon-Chanal A, Webster SP, Vázquez S.

Eur J Med Chem. 2017 Oct 20;139:412-428. doi: 10.1016/j.ejmech.2017.08.003. Epub 2017 Aug 4.

20.

Slow but Steady Wins the Race: Dissimilarities among New Dual Inhibitors of the Wild-Type and the V27A Mutant M2 Channels of Influenza A Virus.

Barniol-Xicota M, Gazzarrini S, Torres E, Hu Y, Wang J, Naesens L, Moroni A, Vázquez S.

J Med Chem. 2017 May 11;60(9):3727-3738. doi: 10.1021/acs.jmedchem.6b01758. Epub 2017 Apr 24.

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