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Items: 1 to 20 of 31

1.

Synthesis and Antileishmanial Activity of 1,2,4,5-Tetraoxanes against Leishmania donovani.

Cabral LIL, Pomel S, Cojean S, Amado PSM, Loiseau PM, Cristiano MLS.

Molecules. 2020 Jan 22;25(3). pii: E465. doi: 10.3390/molecules25030465.

2.

Synthesis and Antimalarial Activity of 1,4-Disubstituted Piperidine Derivatives.

Seck R, Gassama A, Cojean S, Cavé C.

Molecules. 2020 Jan 11;25(2). pii: E299. doi: 10.3390/molecules25020299.

3.

Plasmodium vivax severe imported malaria in two migrants in France.

Izri A, Cojean S, Leblanc C, Cohen Y, Bouchaud O, Durand R.

Malar J. 2019 Dec 16;18(1):422. doi: 10.1186/s12936-019-3067-5.

4.

Synthesis, In Silico, and In Vitro Evaluation of Anti-Leishmanial Activity of Oxadiazoles and Indolizine Containing Compounds Flagged against Anti-Targets.

Stevanovic S, Sencanski M, Danel M, Menendez C, Belguedj R, Bouraiou A, Nikolic K, Cojean S, Loiseau PM, Glisic S, Baltas M, García-Sosa AT.

Molecules. 2019 Apr 2;24(7). pii: E1282. doi: 10.3390/molecules24071282.

5.

In-vitro and in-vivo antileishmanial activity of inexpensive Amphotericin B formulations: Heated Amphotericin B and Amphotericin B-loaded microemulsion.

Rochelle do Vale Morais A, Silva AL, Cojean S, Balaraman K, Bories C, Pomel S, Barratt G, do Egito EST, Loiseau PM.

Exp Parasitol. 2018 Sep;192:85-92. doi: 10.1016/j.exppara.2018.07.017. Epub 2018 Aug 1.

PMID:
30075233
6.

Polysorbate Surfactants as Drug Carriers: Tween 20-Amphotericin B Conjugates as Anti-Fungal and Anti-Leishmanial Agents.

Ravichandran V, Kesavan V, Cojean S, Loiseau PM, Jayakrishnan A.

Curr Drug Deliv. 2018;15(7):1028-1037. doi: 10.2174/1567201815666180503122829.

PMID:
29732967
7.

ABMA, a small molecule that inhibits intracellular toxins and pathogens by interfering with late endosomal compartments.

Wu Y, Pons V, Goudet A, Panigai L, Fischer A, Herweg JA, Kali S, Davey RA, Laporte J, Bouclier C, Yousfi R, Aubenque C, Merer G, Gobbo E, Lopez R, Gillet C, Cojean S, Popoff MR, Clayette P, Le Grand R, Boulogne C, Tordo N, Lemichez E, Loiseau PM, Rudel T, Sauvaire D, Cintrat JC, Gillet D, Barbier J.

Sci Rep. 2017 Nov 14;7(1):15567. doi: 10.1038/s41598-017-15466-7.

8.

Antiprotozoal activity of medicinal plants used by Iquitos-Nauta road communities in Loreto (Peru).

Vásquez-Ocmín P, Cojean S, Rengifo E, Suyyagh-Albouz S, Amasifuen Guerra CA, Pomel S, Cabanillas B, Mejía K, Loiseau PM, Figadère B, Maciuk A.

J Ethnopharmacol. 2018 Jan 10;210:372-385. doi: 10.1016/j.jep.2017.08.039. Epub 2017 Sep 5.

PMID:
28887215
9.

Influence of host factors and parasite biomass on the severity of imported Plasmodium falciparum malaria.

Argy N, Kendjo E, Augé-Courtoi C, Cojean S, Clain J, Houzé P, Thellier M, Hubert V, Deloron P, Houzé S; CNRP study group.

PLoS One. 2017 Apr 14;12(4):e0175328. doi: 10.1371/journal.pone.0175328. eCollection 2017.

10.

Inhibitors of retrograde trafficking active against ricin and Shiga toxins also protect cells from several viruses, Leishmania and Chlamydiales.

Gupta N, Noël R, Goudet A, Hinsinger K, Michau A, Pons V, Abdelkafi H, Secher T, Shima A, Shtanko O, Sakurai Y, Cojean S, Pomel S, Liévin-Le Moal V, Leignel V, Herweg JA, Fischer A, Johannes L, Harrison K, Beard PM, Clayette P, Le Grand R, Rayner JO, Rudel T, Vacus J, Loiseau PM, Davey RA, Oswald E, Cintrat JC, Barbier J, Gillet D.

Chem Biol Interact. 2017 Apr 1;267:96-103. doi: 10.1016/j.cbi.2016.10.005. Epub 2016 Oct 3.

PMID:
27712998
11.

In Silico Mining for Antimalarial Structure-Activity Knowledge and Discovery of Novel Antimalarial Curcuminoids.

Viira B, Gendron T, Lanfranchi DA, Cojean S, Horvath D, Marcou G, Varnek A, Maes L, Maran U, Loiseau PM, Davioud-Charvet E.

Molecules. 2016 Jun 29;21(7). pii: E853. doi: 10.3390/molecules21070853.

12.

A Worldwide Map of Plasmodium falciparum K13-Propeller Polymorphisms.

Ménard D, Khim N, Beghain J, Adegnika AA, Shafiul-Alam M, Amodu O, Rahim-Awab G, Barnadas C, Berry A, Boum Y, Bustos MD, Cao J, Chen JH, Collet L, Cui L, Thakur GD, Dieye A, Djallé D, Dorkenoo MA, Eboumbou-Moukoko CE, Espino FE, Fandeur T, Ferreira-da-Cruz MF, Fola AA, Fuehrer HP, Hassan AM, Herrera S, Hongvanthong B, Houzé S, Ibrahim ML, Jahirul-Karim M, Jiang L, Kano S, Ali-Khan W, Khanthavong M, Kremsner PG, Lacerda M, Leang R, Leelawong M, Li M, Lin K, Mazarati JB, Ménard S, Morlais I, Muhindo-Mavoko H, Musset L, Na-Bangchang K, Nambozi M, Niaré K, Noedl H, Ouédraogo JB, Pillai DR, Pradines B, Quang-Phuc B, Ramharter M, Randrianarivelojosia M, Sattabongkot J, Sheikh-Omar A, Silué KD, Sirima SB, Sutherland C, Syafruddin D, Tahar R, Tang LH, Touré OA, Tshibangu-wa-Tshibangu P, Vigan-Womas I, Warsame M, Wini L, Zakeri S, Kim S, Eam R, Berne L, Khean C, Chy S, Ken M, Loch K, Canier L, Duru V, Legrand E, Barale JC, Stokes B, Straimer J, Witkowski B, Fidock DA, Rogier C, Ringwald P, Ariey F, Mercereau-Puijalon O; KARMA Consortium.

N Engl J Med. 2016 Jun 23;374(25):2453-64. doi: 10.1056/NEJMoa1513137.

13.

Antiplasmodial activity of selected medicinal plants used to treat malaria in Ghana.

Komlaga G, Cojean S, Dickson RA, Beniddir MA, Suyyagh-Albouz S, Mensah ML, Agyare C, Champy P, Loiseau PM.

Parasitol Res. 2016 Aug;115(8):3185-95. doi: 10.1007/s00436-016-5080-8. Epub 2016 May 13.

PMID:
27174028
14.

Highly improved antiparasitic activity after introduction of an N-benzylimidazole moiety on protein farnesyltransferase inhibitors.

Bosc D, Mouray E, Cojean S, Franco CH, Loiseau PM, Freitas-Junior LH, Moraes CB, Grellier P, Dubois J.

Eur J Med Chem. 2016 Feb 15;109:173-86. doi: 10.1016/j.ejmech.2015.12.045. Epub 2015 Dec 29.

PMID:
26774924
15.

In vitro and in vivo antileishmanial properties of a 2-n-propylquinoline hydroxypropyl β-cyclodextrin formulation and pharmacokinetics via intravenous route.

Balaraman K, Vieira NC, Moussa F, Vacus J, Cojean S, Pomel S, Bories C, Figadère B, Kesavan V, Loiseau PM.

Biomed Pharmacother. 2015 Dec;76:127-33. doi: 10.1016/j.biopha.2015.10.028. Epub 2015 Nov 18.

PMID:
26653559
16.

Absence of association between Plasmodium falciparum small sub-unit ribosomal RNA gene mutations and in vitro decreased susceptibility to doxycycline.

Gaillard T, Wurtz N, Houzé S, Sriprawat K, Wangsing C, Hubert V, Lebras J, Nosten F, Briolant S, Pradines B; French National Reference Centre for Imported Malaria Study Group.

Malar J. 2015 Sep 17;14:348. doi: 10.1186/s12936-015-0878-x.

17.

Synthesis of 5-isoxazol-3-yl-pyrimidine nucleosides as potential antileishmanial agents.

Guo S, Wang J, Zhang X, Cojean S, Loiseau PM, Fan X.

Bioorg Med Chem Lett. 2015 Jul 1;25(13):2617-20. doi: 10.1016/j.bmcl.2015.04.097. Epub 2015 May 6.

PMID:
25987374
18.

VFV as a New Effective CYP51 Structure-Derived Drug Candidate for Chagas Disease and Visceral Leishmaniasis.

Lepesheva GI, Hargrove TY, Rachakonda G, Wawrzak Z, Pomel S, Cojean S, Nde PN, Nes WD, Locuson CW, Calcutt MW, Waterman MR, Daniels JS, Loiseau PM, Villalta F.

J Infect Dis. 2015 Nov 1;212(9):1439-48. doi: 10.1093/infdis/jiv228. Epub 2015 Apr 15.

19.

"Squalenoylcurcumin" nanoassemblies as water-dispersible drug candidates with antileishmanial activity.

Cheikh-Ali Z, Caron J, Cojean S, Bories C, Couvreur P, Loiseau PM, Desmaële D, Poupon E, Champy P.

ChemMedChem. 2015 Feb;10(2):411-8. doi: 10.1002/cmdc.201402449. Epub 2014 Dec 18.

PMID:
25523035
20.

Targeting sterol metabolism for the development of antileishmanials.

Pomel S, Cojean S, Loiseau PM.

Trends Parasitol. 2015 Jan;31(1):5-7. doi: 10.1016/j.pt.2014.11.007. Epub 2014 Dec 12.

PMID:
25498194

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