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Items: 1 to 20 of 23


DREADD technology reveals major impact of Gq signaling on cardiac electrophysiology.

Kaiser E, Tian Q, Wagner M, Barth M, Xian W, Schroeder L, Ruppenthal S, Kaestner L, Boehm U, Wartenberg P, Lu H, McMillin SM, Bone DB, Wess J, Lipp P.

Cardiovasc Res. 2018 Oct 13. doi: 10.1093/cvr/cvy251. [Epub ahead of print]


Aberrant Deactivation-Induced Gain of Function in TRPM4 Mutant Is Associated with Human Cardiac Conduction Block.

Xian W, Hui X, Tian Q, Wang H, Moretti A, Laugwitz KL, Flockerzi V, Ruppenthal S, Lipp P.

Cell Rep. 2018 Jul 17;24(3):724-731. doi: 10.1016/j.celrep.2018.06.034.


Does Erythropoietin Regulate TRPC Channels in Red Blood Cells?

Danielczok J, Hertz L, Ruppenthal S, Kaiser E, Petkova-Kirova P, Bogdanova A, Krause E, Lipp P, Freichel M, Kaestner L, Birnbaumer L.

Cell Physiol Biochem. 2017;41(3):1219-1228. doi: 10.1159/000464384. Epub 2017 Mar 6.


Endothelin-1-induced remodelling of murine adult ventricular myocytes.

Viero C, Wegener S, Scholz A, Ruppenthal S, Tian Q, Tabellion W, Kreinest M, Laschke MW, Kaestner L, Lipp P.

Cell Calcium. 2016 Jan;59(1):41-53. doi: 10.1016/j.ceca.2015.12.005. Epub 2016 Jan 5.


Cardiac remodeling in Gαq and Gα11 knockout mice.

Wiesen K, Kaiser E, Schröder L, Scholz A, Ruppenthal S, Reil JC, Backes C, Meese E, Meier C, Bogdanova A, Lipp P, Kaestner L.

Int J Cardiol. 2016 Jan 1;202:836-45. doi: 10.1016/j.ijcard.2015.10.069. Epub 2015 Oct 9.


Genetically Encoded Voltage Indicators in Circulation Research.

Kaestner L, Tian Q, Kaiser E, Xian W, Müller A, Oberhofer M, Ruppenthal S, Sinnecker D, Tsutsui H, Miyawaki A, Moretti A, Lipp P.

Int J Mol Sci. 2015 Sep 8;16(9):21626-42. doi: 10.3390/ijms160921626. Review.


Differential Behavior of Fibroblasts and Epithelial Cells on Structured Implant Abutment Materials: A Comparison of Materials and Surface Topographies.

Nothdurft FP, Fontana D, Ruppenthal S, May A, Aktas C, Mehraein Y, Lipp P, Kaestner L.

Clin Implant Dent Relat Res. 2015 Dec;17(6):1237-49. doi: 10.1111/cid.12253. Epub 2014 Jul 26.


Genetically encoded Ca2+ indicators in cardiac myocytes.

Kaestner L, Scholz A, Tian Q, Ruppenthal S, Tabellion W, Wiesen K, Katus HA, Müller OJ, Kotlikoff MI, Lipp P.

Circ Res. 2014 May 9;114(10):1623-39. doi: 10.1161/CIRCRESAHA.114.303475. Review.


Irisin does not mediate resistance training-induced alterations in resting metabolic rate.

Scharhag-Rosenberger F, Meyer T, Wegmann M, Ruppenthal S, Kaestner L, Morsch A, Hecksteden A.

Med Sci Sports Exerc. 2014 Sep;46(9):1736-43. doi: 10.1249/MSS.0000000000000286.


Irisin and exercise training in humans - results from a randomized controlled training trial.

Hecksteden A, Wegmann M, Steffen A, Kraushaar J, Morsch A, Ruppenthal S, Kaestner L, Meyer T.

BMC Med. 2013 Nov 5;11:235. doi: 10.1186/1741-7015-11-235.


Morphologically homogeneous red blood cells present a heterogeneous response to hormonal stimulation.

Wang J, Wagner-Britz L, Bogdanova A, Ruppenthal S, Wiesen K, Kaiser E, Tian Q, Krause E, Bernhardt I, Lipp P, Philipp SE, Kaestner L.

PLoS One. 2013 Jun 28;8(6):e67697. doi: 10.1371/journal.pone.0067697. Print 2013.


Calcium dysregulation in ventricular myocytes from mice expressing constitutively active Rac1.

Oberhofer M, Tian Q, Ruppenthal S, Wegener S, Reil JC, Körbel C, Hammer K, Menger M, Neuberger HR, Kaestner L, Lipp P.

Cell Calcium. 2013 Jul;54(1):26-36. doi: 10.1016/j.ceca.2013.03.006. Epub 2013 Apr 28.


Mutation of the calmodulin binding motif IQ of the L-type Ca(v)1.2 Ca2+ channel to EQ induces dilated cardiomyopathy and death.

Blaich A, Pahlavan S, Tian Q, Oberhofer M, Poomvanicha M, Lenhardt P, Domes K, Wegener JW, Moosmang S, Ruppenthal S, Scholz A, Lipp P, Hofmann F.

J Biol Chem. 2012 Jun 29;287(27):22616-25. doi: 10.1074/jbc.M112.357921. Epub 2012 May 15.


Gαq and Gα11 contribute to the maintenance of cellular electrophysiology and Ca2+ handling in ventricular cardiomyocytes.

Pahlavan S, Oberhofer M, Sauer B, Ruppenthal S, Tian Q, Scholz A, Kaestner L, Lipp P.

Cardiovasc Res. 2012 Jul 1;95(1):48-58. doi: 10.1093/cvr/cvs162. Epub 2012 May 4.


Dantrolene rescues arrhythmogenic RYR2 defect in a patient-specific stem cell model of catecholaminergic polymorphic ventricular tachycardia.

Jung CB, Moretti A, Mederos y Schnitzler M, Iop L, Storch U, Bellin M, Dorn T, Ruppenthal S, Pfeiffer S, Goedel A, Dirschinger RJ, Seyfarth M, Lam JT, Sinnecker D, Gudermann T, Lipp P, Laugwitz KL.

EMBO Mol Med. 2012 Mar;4(3):180-91. doi: 10.1002/emmm.201100194. Epub 2012 Jan 25.


Functional and morphological preservation of adult ventricular myocytes in culture by sub-micromolar cytochalasin D supplement.

Tian Q, Pahlavan S, Oleinikow K, Jung J, Ruppenthal S, Scholz A, Schumann C, Kraegeloh A, Oberhofer M, Lipp P, Kaestner L.

J Mol Cell Cardiol. 2012 Jan;52(1):113-24. doi: 10.1016/j.yjmcc.2011.09.001. Epub 2011 Sep 10.


Optical action potential screening on adult ventricular myocytes as an alternative QT-screen.

Tian Q, Oberhofer M, Ruppenthal S, Scholz A, Buschmann V, Tsutsui H, Miyawaki A, Zeug A, Lipp P, Kaestner L.

Cell Physiol Biochem. 2011;27(3-4):281-90. doi: 10.1159/000327954. Epub 2011 Apr 1.


Moderate calcium channel dysfunction in adult mice with inducible cardiomyocyte-specific excision of the cacnb2 gene.

Meissner M, Weissgerber P, Londoño JE, Prenen J, Link S, Ruppenthal S, Molkentin JD, Lipp P, Nilius B, Freichel M, Flockerzi V.

J Biol Chem. 2011 May 6;286(18):15875-82. doi: 10.1074/jbc.M111.227819. Epub 2011 Feb 28.


Remodelling of Ca2+ handling organelles in adult rat ventricular myocytes during long term culture.

Hammer K, Ruppenthal S, Viero C, Scholz A, Edelmann L, Kaestner L, Lipp P.

J Mol Cell Cardiol. 2010 Sep;49(3):427-37. doi: 10.1016/j.yjmcc.2010.05.010. Epub 2010 Jun 9.


Isolation and genetic manipulation of adult cardiac myocytes for confocal imaging.

Kaestner L, Scholz A, Hammer K, Vecerdea A, Ruppenthal S, Lipp P.

J Vis Exp. 2009 Sep 17;(31). pii: 1433. doi: 10.3791/1433.

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