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Items: 1 to 20 of 137

1.

VGF-derived peptide TLQP-21 modulates microglial function through C3aR1 signaling pathways and reduces neuropathology in 5xFAD mice.

El Gaamouch F, Audrain M, Lin WJ, Beckmann N, Jiang C, Hariharan S, Heeger PS, Schadt EE, Gandy S, Ehrlich ME, Salton SR.

Mol Neurodegener. 2020 Jan 10;15(1):4. doi: 10.1186/s13024-020-0357-x.

2.

From Egoism to Ecoism: Psychedelics Increase Nature Relatedness in a State-Mediated and Context-Dependent Manner.

Kettner H, Gandy S, Haijen ECHM, Carhart-Harris RL.

Int J Environ Res Public Health. 2019 Dec 16;16(24). pii: E5147. doi: 10.3390/ijerph16245147.

3.

Clarifying the Potential Role of Microbes in Alzheimer's Disease.

Readhead B, Haure-Mirande JV, Ehrlich ME, Gandy S, Dudley JT.

Neuron. 2019 Dec 18;104(6):1036-1037. doi: 10.1016/j.neuron.2019.11.008. No abstract available.

PMID:
31855627
4.

Decrease in p3-Alcβ37 and p3-Alcβ40, products of Alcadein β generated by γ-secretase cleavages, in aged monkeys and patients with Alzheimer's disease.

Hata S, Omori C, Kimura A, Saito H, Kimura N, Gupta V, Pedrini S, Hone E, Chatterjee P, Taddei K, Kasuga K, Ikeuchi T, Waragai M, Nishimura M, Hu A, Nakaya T, Meijer L, Maeda M, Yamamoto T, Masters CL, Rowe CC, Ames D, Yamamoto K, Martins RN, Gandy S, Suzuki T.

Alzheimers Dement (N Y). 2019 Nov 7;5:740-750. doi: 10.1016/j.trci.2019.09.015. eCollection 2019.

5.

Paul Greengard, Ph.D. (1925-2019).

Gandy S, Suzuki T.

Alzheimers Dement. 2019 Sep;15(9):1229-1235. doi: 10.1016/j.jalz.2019.08.001. No abstract available.

6.

Incidence of mild cognitive impairment in World Trade Center responders: Long-term consequences of re-experiencing the events on 9/11/2001.

Clouston SAP, Diminich ED, Kotov R, Pietrzak RH, Richards M, Spiro A 3rd, Deri Y, Carr M, Yang X, Gandy S, Sano M, Bromet EJ, Luft BJ.

Alzheimers Dement (Amst). 2019 Sep 6;11:628-636. doi: 10.1016/j.dadm.2019.07.006. eCollection 2019 Dec.

7.

Relationship of traumatic brain injury to chronic mental health problems and dementia in military veterans.

Elder GA, Ehrlich ME, Gandy S.

Neurosci Lett. 2019 Aug 10;707:134294. doi: 10.1016/j.neulet.2019.134294. Epub 2019 May 26. Review.

PMID:
31141716
8.

Posttraumatic stress disorder and total amyloid burden and amyloid-β 42/40 ratios in plasma: Results from a pilot study of World Trade Center responders.

Clouston SAP, Deri Y, Diminich E, Kew R, Kotov R, Stewart C, Yang X, Gandy S, Sano M, Bromet EJ, Luft BJ.

Alzheimers Dement (Amst). 2019 Feb 28;11:216-220. doi: 10.1016/j.dadm.2019.01.003. eCollection 2019 Dec.

9.

Unexpected systemic phenotypes result from focal combined deficiencies of forebrain insulin receptor/IGF-1 receptor signaling.

Gandy S, Huffman DM.

Proc Natl Acad Sci U S A. 2019 Mar 26;116(13):5852-5854. doi: 10.1073/pnas.1901970116. Epub 2019 Mar 11. No abstract available.

10.

Low-level blast exposure disrupts gliovascular and neurovascular connections and induces a chronic vascular pathology in rat brain.

Gama Sosa MA, De Gasperi R, Perez Garcia GS, Perez GM, Searcy C, Vargas D, Spencer A, Janssen PL, Tschiffely AE, McCarron RM, Ache B, Manoharan R, Janssen WG, Tappan SJ, Hanson RW, Gandy S, Hof PR, Ahlers ST, Elder GA.

Acta Neuropathol Commun. 2019 Jan 9;7(1):6. doi: 10.1186/s40478-018-0647-5.

11.

Correction: Integrative approach to sporadic Alzheimer's disease: deficiency of TYROBP in cerebral Aβ amyloidosis mouse normalizes clinical phenotype and complement subnetwork molecular pathology without reducing Aβ burden.

Haure-Mirande JV, Wang M, Audrain M, Fanutza T, Kim SH, Heja S, Readhead B, Dudley JT, Blitzer RD, Schadt EE, Zhang B, Gandy S, Ehrlich ME.

Mol Psychiatry. 2019 Mar;24(3):472. doi: 10.1038/s41380-018-0301-4.

PMID:
30464330
12.

Integrative approach to sporadic Alzheimer's disease: deficiency of TYROBP in cerebral Aβ amyloidosis mouse normalizes clinical phenotype and complement subnetwork molecular pathology without reducing Aβ burden.

Haure-Mirande JV, Wang M, Audrain M, Fanutza T, Kim SH, Heja S, Readhead B, Dudley JT, Blitzer RD, Schadt EE, Zhang B, Gandy S, Ehrlich ME.

Mol Psychiatry. 2019 Mar;24(3):431-446. doi: 10.1038/s41380-018-0255-6. Epub 2018 Oct 3. Erratum in: Mol Psychiatry. 2018 Nov 21;:.

13.

Integrative approach to sporadic Alzheimer's disease: deficiency of TYROBP in a tauopathy mouse model reduces C1q and normalizes clinical phenotype while increasing spread and state of phosphorylation of tau.

Audrain M, Haure-Mirande JV, Wang M, Kim SH, Fanutza T, Chakrabarty P, Fraser P, St George-Hyslop PH, Golde TE, Blitzer RD, Schadt EE, Zhang B, Ehrlich ME, Gandy S.

Mol Psychiatry. 2019 Sep;24(9):1383-1397. doi: 10.1038/s41380-018-0258-3. Epub 2018 Oct 3.

14.

Blast-induced "PTSD": Evidence from an animal model.

Perez-Garcia G, Gama Sosa MA, De Gasperi R, Tschiffely AE, McCarron RM, Hof PR, Gandy S, Ahlers ST, Elder GA.

Neuropharmacology. 2019 Feb;145(Pt B):220-229. doi: 10.1016/j.neuropharm.2018.09.023. Epub 2018 Sep 15. Review.

PMID:
30227150
15.

The Mount Sinai cohort of large-scale genomic, transcriptomic and proteomic data in Alzheimer's disease.

Wang M, Beckmann ND, Roussos P, Wang E, Zhou X, Wang Q, Ming C, Neff R, Ma W, Fullard JF, Hauberg ME, Bendl J, Peters MA, Logsdon B, Wang P, Mahajan M, Mangravite LM, Dammer EB, Duong DM, Lah JJ, Seyfried NT, Levey AI, Buxbaum JD, Ehrlich M, Gandy S, Katsel P, Haroutunian V, Schadt E, Zhang B.

Sci Data. 2018 Sep 11;5:180185. doi: 10.1038/sdata.2018.185.

16.

iPSC-derived familial Alzheimer's PSEN2 N141I cholinergic neurons exhibit mutation-dependent molecular pathology corrected by insulin signaling.

Moreno CL, Della Guardia L, Shnyder V, Ortiz-Virumbrales M, Kruglikov I, Zhang B, Schadt EE, Tanzi RE, Noggle S, Buettner C, Gandy S.

Mol Neurodegener. 2018 Jun 26;13(1):33. doi: 10.1186/s13024-018-0265-5.

17.

Multiscale Analysis of Independent Alzheimer's Cohorts Finds Disruption of Molecular, Genetic, and Clinical Networks by Human Herpesvirus.

Readhead B, Haure-Mirande JV, Funk CC, Richards MA, Shannon P, Haroutunian V, Sano M, Liang WS, Beckmann ND, Price ND, Reiman EM, Schadt EE, Ehrlich ME, Gandy S, Dudley JT.

Neuron. 2018 Jul 11;99(1):64-82.e7. doi: 10.1016/j.neuron.2018.05.023. Epub 2018 Jun 21.

18.

Psychological variables implied in the therapeutic effect of ayahuasca: A contextual approach.

Franquesa A, Sainz-Cort A, Gandy S, Soler J, Alcázar-Córcoles MÁ, Bouso JC.

Psychiatry Res. 2018 Jun;264:334-339. doi: 10.1016/j.psychres.2018.04.012. Epub 2018 Apr 4.

PMID:
29674223
19.

Integrated biology approach reveals molecular and pathological interactions among Alzheimer's Aβ42, Tau, TREM2, and TYROBP in Drosophila models.

Sekiya M, Wang M, Fujisaki N, Sakakibara Y, Quan X, Ehrlich ME, De Jager PL, Bennett DA, Schadt EE, Gandy S, Ando K, Zhang B, Iijima KM.

Genome Med. 2018 Mar 29;10(1):26. doi: 10.1186/s13073-018-0530-9.

20.

PTSD-Related Behavioral Traits in a Rat Model of Blast-Induced mTBI Are Reversed by the mGluR2/3 Receptor Antagonist BCI-838.

Perez-Garcia G, De Gasperi R, Gama Sosa MA, Perez GM, Otero-Pagan A, Tschiffely A, McCarron RM, Ahlers ST, Elder GA, Gandy S.

eNeuro. 2018 Jan 30;5(1). pii: ENEURO.0357-17.2018. doi: 10.1523/ENEURO.0357-17.2018. eCollection 2018 Jan-Feb.

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