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Items: 1 to 20 of 45


Nicotine instigates podocyte injury via NLRP3 inflammasomes activation.

Singh GB, Kshirasagar N, Patibandla S, Puchchakayala G, Koka S, Boini KM.

Aging (Albany NY). 2019 Dec 13;11(24):12810-12821. doi: 10.18632/aging.102611. Epub 2019 Dec 13.


Simvastatin improves lysosome function via enhancing lysosome biogenesis in endothelial cells.

Zhang Y, Wang YT, Koka S, Zhang Y, Hussain T, Li X.

Front Biosci (Landmark Ed). 2020 Jan 1;25:283-298.


Inflammatory Mediators in Obesity.

Kumar DP, Koka S, Li C, Rajagopal S.

Mediators Inflamm. 2019 Jul 31;2019:9481819. doi: 10.1155/2019/9481819. eCollection 2019. No abstract available.


Podocyte NLRP3 Inflammasome Activation and Formation by Adipokine Visfatin.

Koka S, Xia M, Zhang C, Zhang Y, Li PL, Boini KM.

Cell Physiol Biochem. 2019;53(2):355-365. doi: 10.33594/000000143.


High Mobility Group Box 1 Mediates TMAO-Induced Endothelial Dysfunction.

Singh GB, Zhang Y, Boini KM, Koka S.

Int J Mol Sci. 2019 Jul 22;20(14). pii: E3570. doi: 10.3390/ijms20143570.


Endothelial NLRP3 inflammasome activation and arterial neointima formation associated with acid sphingomyelinase during hypercholesterolemia.

Koka S, Xia M, Chen Y, Bhat OM, Yuan X, Boini KM, Li PL.

Redox Biol. 2017 Oct;13:336-344. doi: 10.1016/j.redox.2017.06.004. Epub 2017 Jun 15.


Sphingolipids in obesity and related complications.

Boini KM, Xia M, Koka S, Gehr TW, Li PL.

Front Biosci (Landmark Ed). 2017 Jan 1;22:96-116. Review.


Characterization and Activation of NLRP3 Inflammasomes in the Renal Medulla in Mice.

Xia M, Abais JM, Koka S, Meng N, Gehr TW, Boini KM, Li PL.

Kidney Blood Press Res. 2016;41(2):208-21. doi: 10.1159/000443424. Epub 2016 Mar 25.


Instigation of NLRP3 inflammasome activation and glomerular injury in mice on the high fat diet: role of acid sphingomyelinase gene.

Boini KM, Xia M, Koka S, Gehr TW, Li PL.

Oncotarget. 2016 Apr 5;7(14):19031-44. doi: 10.18632/oncotarget.8023.


Chronic inhibition of phosphodiesterase 5 with tadalafil attenuates mitochondrial dysfunction in type 2 diabetic hearts: potential role of NO/SIRT1/PGC-1α signaling.

Koka S, Aluri HS, Xi L, Lesnefsky EJ, Kukreja RC.

Am J Physiol Heart Circ Physiol. 2014 Jun 1;306(11):H1558-68. doi: 10.1152/ajpheart.00865.2013. Epub 2014 Apr 11.


Mammalian target of rapamycin (mTOR) inhibition with rapamycin improves cardiac function in type 2 diabetic mice: potential role of attenuated oxidative stress and altered contractile protein expression.

Das A, Durrant D, Koka S, Salloum FN, Xi L, Kukreja RC.

J Biol Chem. 2014 Feb 14;289(7):4145-60. doi: 10.1074/jbc.M113.521062. Epub 2013 Dec 26.


Phosphodiesterase-5 inhibitor tadalafil attenuates oxidative stress and protects against myocardial ischemia/reperfusion injury in type 2 diabetic mice.

Koka S, Das A, Salloum FN, Kukreja RC.

Free Radic Biol Med. 2013 Jul;60:80-8. doi: 10.1016/j.freeradbiomed.2013.01.031. Epub 2013 Feb 4.


Emerging new uses of phosphodiesterase-5 inhibitors in cardiovascular diseases.

Kukreja RC, Salloum FN, Das A, Koka S, Ockaili RA, Xi L.

Exp Clin Cardiol. 2011 Winter;16(4):e30-5.


Non-selective cation channel-mediated Ca2+-entry and activation of Ca2+/calmodulin-dependent kinase II contribute to G2/M cell cycle arrest and survival of irradiated leukemia cells.

Heise N, Palme D, Misovic M, Koka S, Rudner J, Lang F, Salih HR, Huber SM, Henke G.

Cell Physiol Biochem. 2010;26(4-5):597-608. doi: 10.1159/000322327. Epub 2010 Oct 29.


Functional significance of the intermediate conductance Ca2+-activated K+ channel for the short-term survival of injured erythrocytes.

Föller M, Bobbala D, Koka S, Boini KM, Mahmud H, Kasinathan RS, Shumilina E, Amann K, Beranek G, Sausbier U, Ruth P, Sausbier M, Lang F, Huber SM.

Pflugers Arch. 2010 Nov;460(6):1029-44. doi: 10.1007/s00424-010-0878-1. Epub 2010 Sep 21.


A simple and sensitive HPLC fluorescence method for determination of tadalafil in mouse plasma.

Farthing CA, Farthing DE, Koka S, Larus T, Fakhry I, Xi L, Kukreja RC, Sica D, Gehr TW.

J Chromatogr B Analyt Technol Biomed Life Sci. 2010 Oct 15;878(28):2891-5. doi: 10.1016/j.jchromb.2010.07.022. Epub 2010 Aug 3.


Targeting glutathione by dimethylfumarate protects against experimental malaria by enhancing erythrocyte cell membrane scrambling.

Ghashghaeinia M, Bobbala D, Wieder T, Koka S, Brück J, Fehrenbacher B, Röcken M, Schaller M, Lang F, Ghoreschi K.

Am J Physiol Cell Physiol. 2010 Oct;299(4):C791-804. doi: 10.1152/ajpcell.00014.2010. Epub 2010 Jul 14.


Long-acting phosphodiesterase-5 inhibitor tadalafil attenuates doxorubicin-induced cardiomyopathy without interfering with chemotherapeutic effect.

Koka S, Das A, Zhu SG, Durrant D, Xi L, Kukreja RC.

J Pharmacol Exp Ther. 2010 Sep 1;334(3):1023-30. doi: 10.1124/jpet.110.170191. Epub 2010 Jun 11.


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