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Items: 18


Twins with different personalities: STAT5B-but not STAT5A-has a key role in BCR/ABL-induced leukemia.

Kollmann S, Grundschober E, Maurer B, Warsch W, Grausenburger R, Edlinger L, Huuhtanen J, Lagger S, Hennighausen L, Valent P, Decker T, Strobl B, Mueller M, Mustjoki S, Hoelbl-Kovacic A, Sexl V.

Leukemia. 2019 Jan 24. doi: 10.1038/s41375-018-0369-5. [Epub ahead of print]


CDK6 coordinates JAK2 V617F mutant MPN via NF-κB and apoptotic networks.

Uras IZ, Maurer B, Nivarthi H, Jodl P, Kollmann K, Prchal-Murphy M, Milosevic Feenstra JD, Zojer M, Lagger S, Grausenburger R, Grabner B, Holly R, Kavirayani A, Bock C, Gisslinger H, Valent P, Kralovics R, Sexl V.

Blood. 2019 Apr 11;133(15):1677-1690. doi: 10.1182/blood-2018-08-872648. Epub 2019 Jan 11.


Histone deacetylase 1 expression is inversely correlated with age in the short-lived fish Nothobranchius furzeri.

Zupkovitz G, Lagger S, Martin D, Steiner M, Hagelkruys A, Seiser C, Schöfer C, Pusch O.

Histochem Cell Biol. 2018 Sep;150(3):255-269. doi: 10.1007/s00418-018-1687-4. Epub 2018 Jun 28.


The Role of Activator Protein-1 (AP-1) Family Members in CD30-Positive Lymphomas.

Garces de Los Fayos Alonso I, Liang HC, Turner SD, Lagger S, Merkel O, Kenner L.

Cancers (Basel). 2018 Mar 28;10(4). pii: E93. doi: 10.3390/cancers10040093. Review.


MeCP2 recognizes cytosine methylated tri-nucleotide and di-nucleotide sequences to tune transcription in the mammalian brain.

Lagger S, Connelly JC, Schweikert G, Webb S, Selfridge J, Ramsahoye BH, Yu M, He C, Sanguinetti G, Sowers LC, Walkinshaw MD, Bird A.

PLoS Genet. 2017 May 12;13(5):e1006793. doi: 10.1371/journal.pgen.1006793. eCollection 2017 May.


The molecular basis of variable phenotypic severity among common missense mutations causing Rett syndrome.

Brown K, Selfridge J, Lagger S, Connelly J, De Sousa D, Kerr A, Webb S, Guy J, Merusi C, Koerner MV, Bird A.

Hum Mol Genet. 2016 Feb 1;25(3):558-70. doi: 10.1093/hmg/ddv496. Epub 2015 Dec 8.


CD4(+) T cell lineage integrity is controlled by the histone deacetylases HDAC1 and HDAC2.

Boucheron N, Tschismarov R, Goeschl L, Moser MA, Lagger S, Sakaguchi S, Winter M, Lenz F, Vitko D, Breitwieser FP, Müller L, Hassan H, Bennett KL, Colinge J, Schreiner W, Egawa T, Taniuchi I, Matthias P, Seiser C, Ellmeier W.

Nat Immunol. 2014 May;15(5):439-448. doi: 10.1038/ni.2864. Epub 2014 Mar 30. Erratum in: Nat Immunol. 2014 Sep;15(9):894. Goeschl, Lisa [corrected to Göschl, Lisa].


A single allele of Hdac2 but not Hdac1 is sufficient for normal mouse brain development in the absence of its paralog.

Hagelkruys A, Lagger S, Krahmer J, Leopoldi A, Artaker M, Pusch O, Zezula J, Weissmann S, Xie Y, Schöfer C, Schlederer M, Brosch G, Matthias P, Selfridge J, Lassmann H, Knoblich JA, Seiser C.

Development. 2014 Feb;141(3):604-616. doi: 10.1242/dev.100487.


Histone deacetylase inhibitor Trichostatin A induces neural tube defects and promotes neural crest specification in the chicken neural tube.

Murko C, Lagger S, Steiner M, Seiser C, Schoefer C, Pusch O.

Differentiation. 2013 Jan;85(1-2):55-66. doi: 10.1016/j.diff.2012.12.001. Epub 2013 Jan 16.


PDGFR blockade is a rational and effective therapy for NPM-ALK-driven lymphomas.

Laimer D, Dolznig H, Kollmann K, Vesely PW, Schlederer M, Merkel O, Schiefer AI, Hassler MR, Heider S, Amenitsch L, Thallinger C, Staber PB, Simonitsch-Klupp I, Artaker M, Lagger S, Turner SD, Pileri S, Piccaluga PP, Valent P, Messana K, Landra I, Weichhart T, Knapp S, Shehata M, Todaro M, Sexl V, Höfler G, Piva R, Medico E, Ruggeri BA, Cheng M, Eferl R, Egger G, Penninger JM, Jaeger U, Moriggl R, Inghirami G, Kenner L.

Nat Med. 2012 Nov;18(11):1699-704. doi: 10.1038/nm.2966. Epub 2012 Oct 14.


Self-organization phenomena in embryonic stem cell-derived embryoid bodies: axis formation and breaking of symmetry during cardiomyogenesis.

Fuchs C, Scheinast M, Pasteiner W, Lagger S, Hofner M, Hoellrigl A, Schultheis M, Weitzer G.

Cells Tissues Organs. 2012;195(5):377-91. doi: 10.1159/000328712. Epub 2011 Aug 19.


Distinct and redundant functions of histone deacetylases HDAC1 and HDAC2 in proliferation and tumorigenesis.

Jurkin J, Zupkovitz G, Lagger S, Grausenburger R, Hagelkruys A, Kenner L, Seiser C.

Cell Cycle. 2011 Feb 1;10(3):406-12. Epub 2011 Feb 1.


Expression of class I histone deacetylases during chick and mouse development.

Murko C, Lagger S, Steiner M, Seiser C, Schoefer C, Pusch O.

Int J Dev Biol. 2010;54(10):1527-37. doi: 10.1387/ijdb.092971cm.


Crucial function of histone deacetylase 1 for differentiation of teratomas in mice and humans.

Lagger S, Meunier D, Mikula M, Brunmeir R, Schlederer M, Artaker M, Pusch O, Egger G, Hagelkruys A, Mikulits W, Weitzer G, Muellner EW, Susani M, Kenner L, Seiser C.

EMBO J. 2010 Dec 1;29(23):3992-4007. doi: 10.1038/emboj.2010.264. Epub 2010 Oct 22. Erratum in: EMBO J. 2011 Apr 20;30(8):1671.


Epigenetic regulation of a murine retrotransposon by a dual histone modification mark.

Brunmeir R, Lagger S, Simboeck E, Sawicka A, Egger G, Hagelkruys A, Zhang Y, Matthias P, Miller WJ, Seiser C.

PLoS Genet. 2010 Apr 29;6(4):e1000927. doi: 10.1371/journal.pgen.1000927. Erratum in: PLoS Genet. 2011;7(1). doi: 10.1371/annotation/4ec9cbbd-7620-4449-8961-28213e9dadf4.


The specific role of histone deacetylase 2 in adult neurogenesis.

Jawerka M, Colak D, Dimou L, Spiller C, Lagger S, Montgomery RL, Olson EN, Wurst W, Göttlicher M, Götz M.

Neuron Glia Biol. 2010 May;6(2):93-107. doi: 10.1017/S1740925X10000049. Epub 2010 Apr 14.


The cyclin-dependent kinase inhibitor p21 is a crucial target for histone deacetylase 1 as a regulator of cellular proliferation.

Zupkovitz G, Grausenburger R, Brunmeir R, Senese S, Tischler J, Jurkin J, Rembold M, Meunier D, Egger G, Lagger S, Chiocca S, Propst F, Weitzer G, Seiser C.

Mol Cell Biol. 2010 Mar;30(5):1171-81. doi: 10.1128/MCB.01500-09. Epub 2009 Dec 22.


Histone deacetylase HDAC1/HDAC2-controlled embryonic development and cell differentiation.

Brunmeir R, Lagger S, Seiser C.

Int J Dev Biol. 2009;53(2-3):275-89. doi: 10.1387/ijdb.082649rb. Review.

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