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Items: 1 to 20 of 28

1.

The Unsettling Ambiguity of Therapeutic Extracellular Vesicles from Mesenchymal Stromal Cells.

Mitsialis SA.

Am J Respir Cell Mol Biol. 2019 Dec 5. doi: 10.1165/rcmb.2019-0382ED. [Epub ahead of print] No abstract available.

PMID:
31805239
2.

Heme Oxygenase 1 dampens the macrophage sterile inflammasome response and regulates its components in the hypoxic lung.

Vitali SH, Fernandez-Gonzalez A, Nadkarni J, Kwong A, Rose C, Mitsialis SA, Kourembanas S.

Am J Physiol Lung Cell Mol Physiol. 2019 Oct 30. doi: 10.1152/ajplung.00074.2019. [Epub ahead of print]

PMID:
31664855
3.

Mesenchymal stromal cell exosomes prevent and revert experimental pulmonary fibrosis through modulation of monocyte phenotypes.

Mansouri N, Willis GR, Fernandez-Gonzalez A, Reis M, Nassiri S, Mitsialis SA, Kourembanas S.

JCI Insight. 2019 Nov 1;4(21). pii: 128060. doi: 10.1172/jci.insight.128060.

4.

Defining mesenchymal stromal cell (MSC)-derived small extracellular vesicles for therapeutic applications.

Witwer KW, Van Balkom BWM, Bruno S, Choo A, Dominici M, Gimona M, Hill AF, De Kleijn D, Koh M, Lai RC, Mitsialis SA, Ortiz LA, Rohde E, Asada T, Toh WS, Weiss DJ, Zheng L, Giebel B, Lim SK.

J Extracell Vesicles. 2019 Apr 29;8(1):1609206. doi: 10.1080/20013078.2019.1609206. eCollection 2019.

5.

Macrophage Immunomodulation: The Gatekeeper for Mesenchymal Stem Cell Derived-Exosomes in Pulmonary Arterial Hypertension?

Willis GR, Fernandez-Gonzalez A, Reis M, Mitsialis SA, Kourembanas S.

Int J Mol Sci. 2018 Aug 27;19(9). pii: E2534. doi: 10.3390/ijms19092534. Review.

6.

PPARĪ³ agonist pioglitazone reverses pulmonary hypertension and prevents right heart failure via fatty acid oxidation.

Legchenko E, Chouvarine P, Borchert P, Fernandez-Gonzalez A, Snay E, Meier M, Maegel L, Mitsialis SA, Rog-Zielinska EA, Kourembanas S, Jonigk D, Hansmann G.

Sci Transl Med. 2018 Apr 25;10(438). pii: eaao0303. doi: 10.1126/scitranslmed.aao0303.

PMID:
29695452
7.

Reply to Muraca et al.: Exosome Treatment of Bronchopulmonary Dysplasia: How Pure Should Your Exosome Preparation Be?

Mitsialis SA, Willis GR, Fernandez-Gonzalez A, Kourembanas S.

Am J Respir Crit Care Med. 2018 Apr 1;197(7):970. doi: 10.1164/rccm.201710-2066LE. No abstract available.

8.

Toward Exosome-Based Therapeutics: Isolation, Heterogeneity, and Fit-for-Purpose Potency.

Willis GR, Kourembanas S, Mitsialis SA.

Front Cardiovasc Med. 2017 Oct 9;4:63. doi: 10.3389/fcvm.2017.00063. eCollection 2017.

9.

"Good things come in small packages": application of exosome-based therapeutics in neonatal lung injury.

Willis GR, Mitsialis SA, Kourembanas S.

Pediatr Res. 2018 Jan;83(1-2):298-307. doi: 10.1038/pr.2017.256. Epub 2017 Nov 22. Review.

10.

Mesenchymal Stromal Cell Exosomes Ameliorate Experimental Bronchopulmonary Dysplasia and Restore Lung Function through Macrophage Immunomodulation.

Willis GR, Fernandez-Gonzalez A, Anastas J, Vitali SH, Liu X, Ericsson M, Kwong A, Mitsialis SA, Kourembanas S.

Am J Respir Crit Care Med. 2018 Jan 1;197(1):104-116. doi: 10.1164/rccm.201705-0925OC.

11.

Therapeutic Applications of Extracellular Vesicles: Perspectives from Newborn Medicine.

Willis GR, Kourembanas S, Mitsialis SA.

Methods Mol Biol. 2017;1660:409-432. doi: 10.1007/978-1-4939-7253-1_34. Review.

PMID:
28828676
12.

Stem cell-based therapies for the newborn lung and brain: Possibilities and challenges.

Mitsialis SA, Kourembanas S.

Semin Perinatol. 2016 Apr;40(3):138-51. doi: 10.1053/j.semperi.2015.12.002. Epub 2016 Jan 15. Review.

13.

Systemic Administration of Human Bone Marrow-Derived Mesenchymal Stromal Cell Extracellular Vesicles Ameliorates Aspergillus Hyphal Extract-Induced Allergic Airway Inflammation in Immunocompetent Mice.

Cruz FF, Borg ZD, Goodwin M, Sokocevic D, Wagner DE, Coffey A, Antunes M, Robinson KL, Mitsialis SA, Kourembanas S, Thane K, Hoffman AM, McKenna DH, Rocco PR, Weiss DJ.

Stem Cells Transl Med. 2015 Nov;4(11):1302-16. doi: 10.5966/sctm.2014-0280. Epub 2015 Sep 16.

14.

The Sugen 5416/hypoxia mouse model of pulmonary hypertension revisited: long-term follow-up.

Vitali SH, Hansmann G, Rose C, Fernandez-Gonzalez A, Scheid A, Mitsialis SA, Kourembanas S.

Pulm Circ. 2014 Dec;4(4):619-29. doi: 10.1086/678508.

15.

An Argonaute 2 switch regulates circulating miR-210 to coordinate hypoxic adaptation across cells.

Hale A, Lee C, Annis S, Min PK, Pande R, Creager MA, Julian CG, Moore LG, Mitsialis SA, Hwang SJ, Kourembanas S, Chan SY.

Biochim Biophys Acta. 2014 Nov;1843(11):2528-42. doi: 10.1016/j.bbamcr.2014.06.012. Epub 2014 Jun 28.

16.

Endothelial indoleamine 2,3-dioxygenase protects against development of pulmonary hypertension.

Xiao Y, Christou H, Liu L, Visner G, Mitsialis SA, Kourembanas S, Liu H.

Am J Respir Crit Care Med. 2013 Aug 15;188(4):482-91. doi: 10.1164/rccm.201304-0700OC.

17.

Exosomes mediate the cytoprotective action of mesenchymal stromal cells on hypoxia-induced pulmonary hypertension.

Lee C, Mitsialis SA, Aslam M, Vitali SH, Vergadi E, Konstantinou G, Sdrimas K, Fernandez-Gonzalez A, Kourembanas S.

Circulation. 2012 Nov 27;126(22):2601-11. doi: 10.1161/CIRCULATIONAHA.112.114173. Epub 2012 Oct 31.

18.

Mesenchymal stem cell-mediated reversal of bronchopulmonary dysplasia and associated pulmonary hypertension.

Hansmann G, Fernandez-Gonzalez A, Aslam M, Vitali SH, Martin T, Mitsialis SA, Kourembanas S.

Pulm Circ. 2012 Apr-Jun;2(2):170-81. doi: 10.4103/2045-8932.97603.

19.

Improved pulmonary vascular reactivity and decreased hypertrophic remodeling during nonhypercapnic acidosis in experimental pulmonary hypertension.

Christou H, Reslan OM, Mam V, Tanbe AF, Vitali SH, Touma M, Arons E, Mitsialis SA, Kourembanas S, Khalil RA.

Am J Physiol Lung Cell Mol Physiol. 2012 May 1;302(9):L875-90. doi: 10.1152/ajplung.00293.2011. Epub 2012 Jan 27.

20.

Early macrophage recruitment and alternative activation are critical for the later development of hypoxia-induced pulmonary hypertension.

Vergadi E, Chang MS, Lee C, Liang OD, Liu X, Fernandez-Gonzalez A, Mitsialis SA, Kourembanas S.

Circulation. 2011 May 10;123(18):1986-95. doi: 10.1161/CIRCULATIONAHA.110.978627. Epub 2011 Apr 25.

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